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公开(公告)号：KR101976583B1
公开(公告)日：2019-05-09
申请号：KR1020170106077
申请日：2017-08-22
Applicant: 덕성여자대학교 산학협력단
Inventor： 강남희
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公开(公告)号：KR101762013B1
公开(公告)日：2017-07-26
申请号：KR1020150136640
申请日：2015-09-25
Applicant: 덕성여자대학교 산학협력단
Abstract: 본발명에따른 TWO FACTOR 통신채널을활용한사물기기의등록및 비밀키설정방법은, 사물인터넷(Internet of Things, IoT) 환경에서동작하는사물기기가사물기기의식별값및 사물기기에의해생성된제1난수를비접촉근거리통신을이용하여사용자단말로전송하는단계, 사용자단말이관리서버와공유하는보안키로상기식별값및 상기제1난수를암호화한제1-1암호화메시지를생성하여상기관리서버로전송하는단계, 관리서버가미리설정된연산자로제1-1암호화메시지로부터획득한제1난수및 관리서버가생성한제2난수를연산하여 PSK(Pre Shared Key)를생성하고, 보안키로 PSK와제2난수를암호화한제1-2암호화메시지를생성하여사용자단말로전송하는단계, 사용자단말이 PSK를비접촉근거리통신을이용하여사물기기로전송하는단계, 관리서버가 PSK로식별값및 제1난수를암호화한제2암호화메시지를인터넷소켓통신을이용하여사물기기로전송하는단계및 사물기기가 PSK로제2암호화메시지를복호화하여식별값및 제1난수를획득하고, 획득된식별값및 제1난수를전송한식별값및 제1난수와비교하여관리서버를인증하는단계를포함한다.
Abstract translation: 登记和根据本发明的，其目的设备在对象因特网操作利用所述信道的两个因素通信对象装置的由所述识别值与所述对象设备的对象单元所生成的秘密密钥设定方法的环境（东西，的IoT的因特网）， 第一步骤中，用户终端管理服务器和所述共享机密密钥来进行加密的标识值和所述第一随机数和所述管理服务器使用非接触近距离通信发送所述第一随机数到所述用户终端产生第一-第一加密消息 生成步骤中，所述管理服务器是通过计算从预先设定的操作而获得的第二随机数的PSK（预共享密钥）产生的第一随机数和所述管理服务器上升到被发送到1-1加密的消息，和秘密密钥PSK沃赫2 通过加密，用户终端被发送PSK使用非接触式近距离通信对象装置发送到所述用户终端的随机数产生一个第一 - 第二加密消息的步骤中，所述管理服务器是一个标识值以及第一随机数到PSK 加密的第二个加密密钥 使用因特网套接字通信和事物设备发送一个消息给目的设备的步骤解码PSK罗塞塔第二加密消息，以获得所述标识值和所述第一随机数，并将所获得的标识值和所述第一随机数识别值，以及 并与第一个随机数进行比较来验证管理服务器。
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公开(公告)号：KR101620158B1
公开(公告)日：2016-05-13
申请号：KR1020140028401
申请日：2014-03-11
Applicant: 덕성여자대학교 산학협력단
IPC: C07D215/06 , C07D215/08
Abstract: 본발명은 2-할로벤조산으로부터 1-알킬-2-페닐-4-퀴놀론을제조하는신규한제조방법을제공한다. 본발명의제조방법은저렴한출발물질로서 2-할로벤조산을이용하여간단한반응조건및 단순화된단계를통해 1-알킬-2-페닐-4-퀴놀론을고수율로합성할수 있는장점이있다.
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公开(公告)号：KR1020150106483A
公开(公告)日：2015-09-22
申请号：KR1020140028401
申请日：2014-03-11
Applicant: 덕성여자대학교 산학협력단
IPC: C07D215/06 , C07D215/08
CPC classification number: C07D215/06 , C07D215/08
Abstract: 본 발명은 2-할로벤조산으로부터 1-알킬-2-페닐-4-퀴놀론을 제조하는 신규한 제조방법을 제공한다. 본 발명의 제조 방법은 저렴한 출발물질로서 2-할로벤조산을 이용하여 간단한 반응조건 및 단순화된 단계를 통해 1-알킬-2-페닐-4-퀴놀론을 고수율로 합성할 수 있는 장점이 있다.
Abstract translation: 提供了一种从2-卤代苯甲酸合成1-烷基-2-苯基-4-喹诺酮的新方法。 本发明的合成方法通过2-卤代苯甲酸酯作为廉价起始原料，在简单的反应条件下，通过简单的阶段，可以高收率合成1-烷基-2-苯基-4-喹诺酮。
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85.发明授权
公开(公告)号：KR101498481B1
公开(公告)日：2015-03-04
申请号：KR1020120104016
申请日：2012-09-19
Applicant: 덕성여자대학교 산학협력단 , 대한민국 (식품의약품안전처장)
Abstract: 본 발명은 신장독성 및 부작용 유발 약물 검색용 바이오마커 및 이를 이용한 검색 방법에 관한 것으로, 구체적으로 다양한 신장독성 유발 약물에 공통적으로 유전자 발현이 증가 또는 감소하는 바이오마커 및 이를 이용한 신장독성 및 부작용 유발 약물 검색 방법에 관한 것이다. 약물에 의한 신장 독성이 유발된 인간 신장 상피 세포주의 배양액에서 PKM2(pyruvate kinase isozyme M2)와 EEF1G(eukaryotic elongation factor 1-gamma)가 유효하게 증가함을 확인하였으며, 이러한 결과는 인간 신장 정상 상피 세포주를 이용한 독성 평가에 유용하게 이용할 수 있다. 본 발명의 바이오마커는 새로운 신장독성 및 부작용의 위험성을 지닌 약물 또는 화학물질을 모니터링 및 판정하는데 유용하게 사용될 수 있으며, 신장독성을 일으키는 작용 기작을 규명하는 도구로이용될 수 있다.
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Patent Agency Ranking
公开(公告)号：KR1020140049294A
公开(公告)日：2014-04-25
申请号：KR1020120115392
申请日：2012-10-17
Applicant: 덕성여자대학교 산학협력단
IPC: A23L3/3472 , A23B7/153
Abstract: The present invention relates to a natural anti-browning composition containing salvia miltiorrhiza extracts. More specifically, the salvia miltiorrhiza extracts of the present invention effectively prevent the browning of fruits and vegetables since the extracts provide improved polyphenol oxidase activity inhibitory effect. According to one embodiment of the present invention, provided is a natural anti-browning composition containing salvia miltiorrhiza extracts as an active ingredient to prevent the browning of fruits and vegetables. [Reference numerals] (AA) Untreated; (BB) Salvia miltiorrhiza extract; (CC) Salvia miltiorrhiza ethanol extract treatment
Abstract translation: 本发明涉及含有丹参提取物的天然抗褐变组合物。 更具体地，本发明的丹参提取物有效地防止了水果和蔬菜的褐变，因为提取物提供了改善的多酚氧化酶活性抑制作用。 根据本发明的一个实施方案，提供了含有丹参提取物作为有效成分的天然抗褐变组合物，以防止水果和蔬菜的褐变。 （标号）（AA）未处理; （BB）丹参提取物; （CC）丹参乙醇提取物处理
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公开(公告)号：KR1020140003220A
公开(公告)日：2014-01-09
申请号：KR1020120071223
申请日：2012-06-29
Applicant: 덕성여자대학교 산학협력단 , 대한민국(농촌진흥청장)
CPC classification number: A23B7/0056 , A23B7/0215
Abstract: The present invention relates to a method of maintaining the freshness of cut lotus root, which comprises a step of immersing lotus root in purified water; a step of processing the lotus root with heat at a first heat treatment temperature for a first heat treatment time; and a step of removing purified water remaining on the surface of the lotus root, wherein the first heat treatment temperature is 30°C or higher and 80°C or less, and the first heat treatment time is 30 seconds or more and one minute or less. According to the present invention, the heat processed lotus root has an improved quality and effects capable of a long term storage and preservation. [Reference numerals] (AA) Start; (BB) End; (S1100) Wash surface of lotus root; (S1200) Peel surface of lotus root and cut; (S1300) Immerse lotus root in purified water; (S1400) Process lotus root with heat; (S1500) Naturally dry lotus root; (S1600) Preserve lotus root at low temperature
Abstract translation: 本发明涉及一种维持切割莲藕的新鲜度的方法，其包括将莲藕浸入净化水中的步骤; 在第一热处理温度下进行热处理第一热处理时间的步骤; 以及除去残留在莲藕表面的净化水的步骤，其中第一热处理温度为30℃以上且80℃以下，第一热处理时间为30秒以上1分钟以上 减。 根据本发明，热处理莲藕具有能够长期保存和保存的质量和效果的改善。 （附图标记）（AA）开始; （BB）结束; （S1100）清洗莲藕表面; （S1200）莲藕表皮切割; （S1300）将莲藕浸入纯净水中; （S1400）加热加工莲藕; （S1500）天然干藕; （S1600）在低温下保存莲藕
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公开(公告)号：KR1020130041846A
公开(公告)日：2013-04-25
申请号：KR1020130022979
申请日：2013-03-04
Applicant: 덕성여자대학교 산학협력단
IPC: C07D335/04 , A61K31/382 , A61P35/00 , A61P39/06
Abstract: PURPOSE: A thioflavanone compound with anticancer and antioxidative activities is provided to effectively suppress and treat aging and disorders due to reactive oxygen. CONSTITUTION: A thioflavanone compound with anticancer and antioxidative activities is denoted by chemical formula 1. A composition with anticancer and antioxidative activities contains pharmaceutically effective amount of the thioflavanone compound. A method for preparing thioflavanone comprises: a step of adding lithium diisopropyl amide(LDA, 4.0 mmol) to a solution containing 2'-mercapto acetophenone and THF(9ml) under an argon atmosphere at -15 deg. C and stirring for 1.5 hours; and a step of adding benzaldehyde(212 mg, 2.0 mmol).
Abstract translation: 目的：提供具有抗癌和抗氧化活性的硫代黄酮化合物，以有效抑制和治疗老化和由活性氧引起的疾病。 构成：具有抗癌和抗氧化活性的硫代黄酮化合物由化学式1表示。具有抗癌和抗氧化活性的组合物含有药学上有效量的硫代黄酮化合物。 制备硫代黄烷酮的方法包括：在-15℃下在氩气氛下，向含有2'-巯基苯乙酮和THF（9ml）的溶液中加入二异丙基酰胺锂（LDA，4.0mmol）的步骤。 并搅拌1.5小时; 和加入苯甲醛（212mg，2.0mmol）的步骤。
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公开(公告)号：KR1020120135778A
公开(公告)日：2012-12-17
申请号：KR1020110054686
申请日：2011-06-07
Applicant: 덕성여자대학교 산학협력단
IPC: A23B7/153 , A23L3/3454 , A23L5/41
CPC classification number: A23L2/44 , A23B7/154 , A23L2/02 , A23L3/3472
Abstract: PURPOSE: An anti-browning composition containing a citrus peel extract is provided to use natural plant extracts as an active ingredient for improving the marketability of fresh-cut agricultural products. CONSTITUTION: An anti-browning composition for fruits and vegetables include 0.01-100wt% of citrus peel extract as an active ingredient. A user can prevent the browning of the fruits and vegetables by processing the fruits and vegetables with the composition using one of the following steps: soaking the fruits and vegetables in the anti-browning composition; or inserting the anti-browning composition into fruit and vegetable juice. [Reference numerals] (AA) Non-processed; (BB) Processed with citrus peel hot water extract; (CC) Processed with citrus peel ethanol extract
Abstract translation: 目的：提供含有柑橘皮提取物的抗褐变组合物，以天然植物提取物为活性成分，提高鲜切农产品的销售性。 构成：水果和蔬菜的抗褐变组合物含有0.01-100重量％的柑橘皮提取物作为活性成分。 用户可以通过以下步骤之一来处理水果和蔬菜以防止水果和蔬菜的褐变：将水果和蔬菜浸泡在抗褐变组合物中; 或将抗褐变组合物插入水果和蔬菜汁中。 （附图标记）（AA）未加工; （BB）加工柑橘皮热水提取物; （CC）用柑橘皮乙醇提取物处理
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公开(公告)号：KR1020120131645A
公开(公告)日：2012-12-05
申请号：KR1020110049962
申请日：2011-05-26
Applicant: 덕성여자대학교 산학협력단
CPC classification number: A61K31/35 , A23L33/10 , A23V2002/00 , A23V2200/308 , A61K31/352
Abstract: PURPOSE: A composition containing genipin for preventing or treating breast cancer is provided to suppress breast cell invasion. CONSTITUTION: A pharmaceutical composition for preventing or treating breast cancer contains genipin as an active ingredient. The pharmaceutical composition additionally contains an anticancer material or apoptosis inducer. The anticancer material is a cancer cell-specific antibody, a nucleic acid molecule which specifically suppresses expression of an anticancer gene, 5-fluorouracil, methotrxate, or doxorubicin. The antibody is a monoclonal antibody, a polyclonal antibody, a chimera antibody, a humanized antibody, or human antibody. A health food for treating breast cancer contains genipin as an active ingredient. [Reference numerals] (AA) Cell survival rate(% with respect to a control group); (BB) Genipin
Abstract translation: 目的：提供含有用于预防或治疗乳腺癌的京尼平的组合物以抑制乳腺细胞侵袭。 构成：用于预防或治疗乳腺癌的药物组合物含有京尼平作为活性成分。 药物组合物另外含有抗癌物质或细胞凋亡诱导剂。 抗癌材料是癌细胞特异性抗体，特异性抑制抗癌基因表达的核酸分子，5-氟尿嘧啶，甲氨蝶呤或多柔比星。 抗体是单克隆抗体，多克隆抗体，嵌合体抗体，人源化抗体或人抗体。 用于治疗乳腺癌的保健食品含有京尼平作为活性成分。 （附图标记）（AA）细胞存活率（相对于对照组的％）; （BB）Genipin
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