1,4―BDO 생산을 위한 유전자 스크리닝 방법
    83.
    发明公开
    1,4―BDO 생산을 위한 유전자 스크리닝 방법 审中-实审
    鉴定1,4-BDO生产基因的筛选方法

    公开(公告)号:KR1020150023175A

    公开(公告)日:2015-03-05

    申请号:KR1020130100567

    申请日:2013-08-23

    Abstract: The present invention relates to a method for screening genes used for increasing 1,4-butanediol (BDO) production by using proteomics data. In the present invention, 1,4-BDO productivity is increased when a Ncgl0630 (citrate synthase) protein and a Ncgl2145 (hypothetical protein) protein are overly expressed wherein the Ncgl0630 (citrate synthase) protein and the Ncgl2145 (hypothetical protein) protein are screened via the method which is used to find proteins related to 1,4-BDO productivity and accordingly increases productivity, thereby being widely applicable industrially.

    Abstract translation: 本发明涉及通过使用蛋白质组学数据筛选用于增加1,4-丁二醇(BDO)生产的基因的方法。 在本发明中,当Ncgl0630(柠檬酸合成酶)蛋白和Ncgl2145(假想蛋白))蛋白被过度表达时,其中筛选出Ncgl0630(柠檬酸合成酶)蛋白和Ncgl2145(假想蛋白))蛋白质时,1,4-BDO生产力增加 通过用于发现与1,4-BDO生产率相关的蛋白质的方法,从而提高生产率,从而在工业上广泛应用。

    1,4-BDO 생성능이 개선된 변이 미생물 및 이를 이용한 1,4-BDO 의 제조방법
    88.
    发明公开
    1,4-BDO 생성능이 개선된 변이 미생물 및 이를 이용한 1,4-BDO 의 제조방법 审中-实审
    具有改善1,4-BDO生产能力的突变微生物及其制备1,4-BDO的方法

    公开(公告)号:KR1020140015086A

    公开(公告)日:2014-02-06

    申请号:KR1020120082815

    申请日:2012-07-27

    Abstract: One embodiment of the present invention relates to a metabolism network model of Corynebacterium glutamicum for producing 1,4-BDO by Corynebacterium glutamicum, which is a strain that does not produce 1,4-BDO in a natural state. On the basis of the network model, metabolic properties of Corynebacterium glutamicum are analyzed. By predicting effects of a deletion target enzyme (ldhA, mqo or mdh) in a state in which Cat1, sucD, 4hbD, cat2 and adhE are included, and removing them, production efficiency of 1,4-BDO and increase of 1,4-BDO under the same fermentation conditions are confirmed. In addition, transformation microorganism produced by the method can produce 1,4-BDO in high efficiency, and therefore, can be effectively used in the industries.

    Abstract translation: 本发明的一个实施方案涉及谷氨酸棒杆菌的代谢网络模型,用于通过谷氨酸棒杆菌生产1,4-BDO,其是在天然状态下不产生1,4-BDO的菌株。 在网络模型的基础上,分析谷氨酸棒杆菌的代谢特性。 通过预测在包含Cat1,sucD,4hbD,cat2和adhE的状态下缺失目标酶(ldhA,mqo或mdh)的作用并除去它们,1,4-BDO的生产效率和增加1,4 -BDO在相同的发酵条件下得到确认。 另外,通过该方法生产的转化微生物可以高效率地生产1,4-BDO,因此可以有效地用于工业中。

    복합 음극 활물질, 이의 제조방법 및 이를 포함하는 리튬 이차 전지
    90.
    发明公开
    복합 음극 활물질, 이의 제조방법 및 이를 포함하는 리튬 이차 전지 审中-实审
    复合负极活性材料,其制备方法和包含该组合物的锂二次电池

    公开(公告)号:KR1020130056668A

    公开(公告)日:2013-05-30

    申请号:KR1020110122392

    申请日:2011-11-22

    Abstract: PURPOSE: A composite negative active material is provided to improve lifetime and structure stability, thereby improving lifetime of a lithium secondary battery. CONSTITUTION: A composite negative active material comprises a porous carbon material; and a metal nanostructure arranged in one or more pores inside or on the surface of the porous carbon material. The metal nanocomposite is grown on the basis of a metal catalyst particle arranged inside or on the surface of the porous carbon material. A lithium secondary battery comprises a positive electrode which includes a positive electrode active material, a negative electrode which includes a negative electrode active material; and electrolyte which is inserted between the positive electrode and negative electrode. The negative electrode active material comprises the composite negative electrode active material.

    Abstract translation: 目的:提供复合负极活性材料,以改善寿命和结构稳定性,从而提高锂二次电池的使用寿命。 构成:复合负极活性材料包括多孔碳材料; 以及布置在多孔碳材料表面内或表面上的一个或多个孔中的金属纳米结构。 金属纳米复合材料基于布置在多孔碳材料的内部或表面上的金属催化剂颗粒生长。 锂二次电池包括正极,其包括正极活性物质,负极包括负极活性物质; 以及插入在正极和负极之间的电解质。 负极活性物质由复合负极活性物质构成。

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