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公开(公告)号：BR9611383A
公开(公告)日：1999-01-26
申请号：BR9611383
申请日：1996-10-30
Applicant: BASF AG
Inventor： RITTER KURT , BERNARD HARALD , HAUPT ANDREAS , AMBERG WILHELM , BUSCHMANN ERNST , JANSSEN BERND , MUELLER STEFAN , KLING ANDREAS , ROBINSON SIMON , ARRUDA MONIKA DE , BARLOZZARI TERESA , ZIERKE THOMAS
Abstract: Novel peptides of the formulaA-B-D-E-F-L,wherein A, B, D, E, F, and L have the meanings stated in the specification, and their preparation are disclosed. The novel compounds are suitable for controlling diseases.
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82.发明专利
公开(公告)号：CA2297164A1
公开(公告)日：1998-09-17
申请号：CA2297164
申请日：1998-03-05
Applicant: BASF AG
Inventor： RITTER KURT , KLING ANDREAS , AMBERG WILHELM , JANSSEN BERND , HAUPT ANDREAS , BARLOZZARI TERESA
Abstract: The present invention relates to novel peptides useful as anti-cancer agents. The compounds of the invention are of Formula (I): A - B - D - E - F - G; A, B, D, and E are .alpha.-amino acid residues. In one embodiment, F is an azacycloalkanecarboxylic acid residue. In this embodiment, G is a monovalent radical, for example, a hydrogen atom, an alkyl group, an aryl group, or a heteroaryl group. In another embodiment, F is an azacycloalkyl group and G is a heteroaryl group connected to F by a carbon-carbon bond. In another embodiment, the invention includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula (I) in a pharmaceutically acceptable composition.
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公开(公告)号：NO982100L
公开(公告)日：1998-05-08
申请号：NO982100
申请日：1998-05-08
Applicant: BASF AG
Inventor： KLING ANDREAS , JANSSEN BERND , AMBERG WILHELM , HAUPT ANDREAS , RITTER KURT , BUSCHMANN ERNST , BERNARD HARALD , MUELLER STEFAN , ZIERKE THOMAS , BARLOZZARI TERESA , ARRUDA MONIKA DE , ROBINSON SIMON
Abstract: Novel peptides of the formulaA-B-D-E-F-L,wherein A, B, D, E, F, and L have the meanings stated in the specification, and their preparation are disclosed. The novel compounds are suitable for controlling diseases.
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公开(公告)号：AU679479B2
公开(公告)日：1997-07-03
申请号：AU5695994
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：CZ9501575A3
公开(公告)日：1996-01-17
申请号：CZ157595
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
IPC: A61K38/00 , A61K38/08 , A61P35/00 , C07K1/00 , C07K5/02 , C07K5/027 , C07K7/02 , C07K7/06 , A61K38/07
CPC classification number: C07K7/02 , A61K38/00 , C07K5/0205
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Patent Agency Ranking
公开(公告)号：PL309353A1
公开(公告)日：1995-10-02
申请号：PL30935393
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：ZA939389B
公开(公告)日：1995-06-15
申请号：ZA939389
申请日：1993-12-15
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：DE69803792D1
公开(公告)日：2002-03-21
申请号：DE69803792
申请日：1998-09-24
Applicant: BASF AG
Inventor： BARLOZZARI TERESA , BANERJEE SUBHASHIS , HAUPT ANDREAS
Abstract: The present invention provides compositions and methods for the treatment of rheumatoid arthritis in a subject wherein one or more compounds of Formula I as defined herein alone or in combination with one or more other antiarthritic drugs provide suppression of rheumatoid arthritis.
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公开(公告)号：HU0103560A2
公开(公告)日：2002-02-28
申请号：HU0103560
申请日：1999-06-23
Applicant: BASF AG
Inventor： AMBERG WILHELM , BARLOZZARI TERESA , HAUPT ANDREAS , JANSSEN BERND , KLING ANDREAS , RITTER KURT
Abstract: Compounds of the present invention include cell growth inhibitors which are peptides of Formula IA-B-D-E-F-G(I)and acid salts thereof, wherein A, D, and E are alpha -amino acid residues, B is an alpha -amino acid residue or an alpha -hydroxy acid residue, F is an aminobenzoic acid residue or an aminocycloalkanecarboxylic acid residue, and G is a monovalent radical, such as, for example, a hydrogen atom, an amino group, an alkyl group, an alkylene alkyl ether, an alkylene alkyl thioether, an alkylene aldehyde, an alkylene amide, a beta -hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, an oximato group, an alkylene aryl group, an alkylene ester, an alkylene sulfoxide or an alkylene sulfone. Another aspect of the present invention includes pharmaceutical compositions comprising a compound of Formula I and a pharmaceutically acceptable carrier. An additional embodiment of the present invention is a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.
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90.发明专利
公开(公告)号：AU744511B2
公开(公告)日：2002-02-28
申请号：AU6448298
申请日：1998-03-05
Applicant: BASF AG
Inventor： RITTER KURT , AMBERG WILHELM , BARLOZZARI TERESA , HAUPT ANDREAS , JANSSEN BERND , KLING ANDREAS
Abstract: The present invention relates to novel peptides useful as anti-cancer agents. The compounds of the invention are of Formula I,A-B-D-E-F-G(I)A, B, D, and E are alpha -amino acid residues. In one embodiment, F is an azacycloalkanecarboxylic acid residue. In this embodiment, G is a monovalent radical, for example, a hydrogen atom, an alkyl group, an aryl group, or a heteroaryl group. In another embodiment, F is an azacycloalkyl group and G is a heteroaryl group connected to F by a carbon-carbon bond. In another embodiment, the invention includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.
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