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公开(公告)号:AU2015203152B2
公开(公告)日:2017-01-05
申请号:AU2015203152
申请日:2015-06-12
Applicant: MICELL TECHNOLOGIES INC
Inventor: TAYLOR CHARLES DOUGLAS , MCCLAIN JAMES B , SMOKE CLINT , COLE MICHAEL E , DEYOUNG JAMES
Abstract: H: \xd\Interwoven\NRPortbl\DCC\SXD\7897863_1.doc-6/10/2015 A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate; wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent. CO, =3) LU i C/)3 hI xL 0'01 W uiI
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公开(公告)号:AU2013331003B2
公开(公告)日:2016-11-24
申请号:AU2013331003
申请日:2013-10-18
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , FAGAN MEAGAN M
Abstract: A medical device that releases a pharmaceutical agent to a target site is disclosed. The medical device includes a balloon, and a coating on at least a portion of the balloon. The coating includes particles of a pharmaceutical agent. Each particle of the particles of the pharmaceutical agent is at least partially encapsulated in a polymer material. A method of releasing a pharmaceutical agent at a target site is also disclosed. The method includes the steps of providing a device including a balloon, and a coating on at least a portion of the balloon, the coating including particles of a pharmaceutical agent, and each particle of the pharmaceutical agent is at least partially encapsulated in a polymer material; positioning the device to allow the balloon to reach the target site; and inflating the balloon of the device.
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公开(公告)号:AU2015200571B2
公开(公告)日:2016-11-17
申请号:AU2015200571
申请日:2015-02-06
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS
Abstract: Provided herein is a coated coronary stent, comprising: a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
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公开(公告)号:BRPI0910969A2
公开(公告)日:2016-01-05
申请号:BRPI0910969
申请日:2009-04-17
Applicant: MICELL TECHNOLOGIES INC
Inventor: TAYLOR DOUGLAS , MCCLAIN JAMES B
IPC: A61F13/00
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公开(公告)号:AU2014248508A1
公开(公告)日:2015-11-05
申请号:AU2014248508
申请日:2014-03-12
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , BURGERMEISTER ROBERT STEVEN
IPC: A61F2/00
Abstract: A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts. The interconnected polymer struts defines a plurality of deformable cells. The polymer struts have an average strut thickness of no more than about 120 μι&eegr;. Methods for making the bioabsorbable biomedical implant, including the methods for making the polymer materials for the tubular scaffold, are also disclosed.
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公开(公告)号:CA2667228C
公开(公告)日:2015-07-14
申请号:CA2667228
申请日:2007-10-23
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUG , DICKINSON ED , WORM STEVE
IPC: B05D1/06
Abstract: A stent holder for mounting and electrically charging a stent during coating of the stent using dry particles, the particles comprising inert polymers, pharmaceutical or biological agents, is provided. An assembly for supporting and electrically charging a stent during the coating of the stent using dry particles, the particles comprising inert polymers, pharmaceutical or biological agents, is provided. A chamber for creating an electrical field around a stent and for supporting, electrically charging, and exposing the stent to dry particles, the particles comprising inert polymers, pharmaceutical or biological agents, is provided. A method for creating an electrical field around a stent and for supporting, electrically charging, and exposing the stent to dry particles comprising inert polymers, pharmaceutical or biological agents is provided.
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公开(公告)号:AU2015203152A1
公开(公告)日:2015-07-09
申请号:AU2015203152
申请日:2015-06-12
Applicant: MICELL TECHNOLOGIES INC
Inventor: TAYLOR CHARLES DOUGLAS , MCCLAIN JAMES B , SMOKE CLINT , COLE MICHAEL E , DEYOUNG JAMES
Abstract: H: \xd\Interwoven\NRPortbl\DCC\SXD\7897863_1.doc-6/10/2015 A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate; wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent. CO, =3) LU i C/)3 hI xL 0'01 W uiI
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公开(公告)号:AU2013331003A1
公开(公告)日:2015-05-07
申请号:AU2013331003
申请日:2013-10-18
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , FAGAN MEAGAN M
Abstract: A medical device that releases a pharmaceutical agent to a target site is disclosed. The medical device includes a balloon, and a coating on at least a portion of the balloon. The coating includes particles of a pharmaceutical agent. Each particle of the particles of the pharmaceutical agent is at least partially encapsulated in a polymer material. A method of releasing a pharmaceutical agent at a target site is also disclosed. The method includes the steps of providing a device including a balloon, and a coating on at least a portion of the balloon, the coating including particles of a pharmaceutical agent, and each particle of the pharmaceutical agent is at least partially encapsulated in a polymer material; positioning the device to allow the balloon to reach the target site; and inflating the balloon of the device.
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公开(公告)号:AU2015200571A1
公开(公告)日:2015-04-09
申请号:AU2015200571
申请日:2015-02-06
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS
Abstract: Provided herein is a coated coronary stent, comprising: a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
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公开(公告)号:CA2615452C
公开(公告)日:2015-03-31
申请号:CA2615452
申请日:2006-07-14
Applicant: MICELL TECHNOLOGIES INC
Inventor: TAYLOR DOUG , MCCLAIN JAMES B , SMOKE CLINT , COLE MIKE , DEYOUNG JAMES
Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
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