Abstract:
The present invention relates to a vaccine composition comprising domestic predominant epidemic genotype strains of bovine viral diarrhea virus for preventing or treating bovine viral diarrhea. When preparing a vaccine by mixing GB44-1 strain, GB45-1 strain, and 08Q723 strain which are the bovine viral diarrhea virus according to the present invention, the vaccine can be valuably used as an effective vaccine for preventing or treating the bovine viral diarrhea since the vaccine is suitable for domestic genotypes and has an outstanding immune function compared to a conventional vaccine, and solves a problem of a conventional vaccine for the bovine viral diarrhea.