公开(公告)号：KR1020130019725A

公开(公告)日：2013-02-27

申请号：KR1020110081853

申请日：2011-08-17

Applicant: 전남대학교산학협력단

Inventor： 전우진 ,  유양희 ,  김경미 ,  윤호근 ,  이유현 ,  배동혁 ,  김진영 ,  성혜미

IPC: A61K36/9066 ,  A61P1/16

Abstract: PURPOSE: A pharmaceutical composition containing a fraction of a Curcuma Longa L. extract for preventing alcoholic liver damage is provided to suppress generation of alcoholic lipid peroxide and to enhance antioxidation. CONSTITUTION: A pharmaceutical composition for preventing alcoholic liver damage contains a fraction of a Curcuma Longa L. water extract as an active ingredient. The fraction is prepared by extracting Curcuma Longa L. with hot water and fractioning with chloroform. The liver damage is alcoholic fatty liver, alcoholic hepatitis, or alcoholic cirrhosis. A health functional food for preventing alcoholic liver damage contains the fraction as an active ingredient.

Abstract translation: 目的：提供一种含有姜黄姜黄提取物用于预防酒精性肝损伤的药物组合物，以抑制酒精性脂质过氧化物的产生并增强抗氧化作用。 构成：用于预防酒精性肝损伤的药物组合物含有一部分作为活性成分的姜黄龙提取物。 通过用热水提取姜黄和用氯仿分级制备级分。 肝损害是酒精性脂肪肝，酒精性肝炎或酒精性肝硬化。 用于预防酒精性肝损伤的健康功能食品包含该部分作为活性成分。

公开(公告)号：KR101407150B1

公开(公告)日：2014-07-14

申请号：KR1020120112449

申请日：2012-10-10

Applicant: 한국인스팜(주) ,  전남대학교산학협력단

Inventor： 서은진 ,  유양희 ,  전우진 ,  김용재 ,  오규철 ,  김선오 ,  이유현

IPC: A61K36/73 ,  A61K36/738 ,  A61P25/00

Abstract: 본 발명은 해당화 줄기 및 잎 추출물을 함유하는 조성물에 관한 것으로, 해당화 줄기 및 잎을 다양한 용매를 이용하여 추출, 농축하여 수득 가능한 분말 또는 엑기스를 포함하는 수면부족상태로 기인한 스트레스관련 질환에 대한 억제, 예방 및 개선을 위한 약학조성물 및 건강기능식품에 관한 것으로, 본 발명에 의한 해당화 줄기 및 잎 추출물은 랫트에서 수면박탈에 대항하여 생존율 증가, 꾸벅임 감소, 코티졸 함량 감소효과 및 신경세포 보호효과가 탁월함을 확인하였다.

公开(公告)号：KR1020140026737A

公开(公告)日：2014-03-06

申请号：KR1020120092198

申请日：2012-08-23

Applicant: 한국인스팜(주) ,  재단법인 전남생물산업진흥원 ,  전남대학교산학협력단

Inventor： 전우진 ,  김용재 ,  오규철 ,  김선오 ,  이정민 ,  황권택 ,  이유현

IPC: A61K36/9066 ,  A61P1/16 ,  A61P25/32

Abstract: The present invention relates to a composition containing fermented Curcuma longa powder for treating alcoholic liver damage. The fermented Curcuma longa powder of the present invention is obtained by fermenting materials for the fermented Curcuma longa powder using Aspergillus oryzae, and sterilizing and drying the materials, and shows a strong liver damage control function in an alcoholic liver damage model. The composition can be practically used for treatment and prevention food for alcoholic liver damage, medical products, and outer medical products using the fermented Curcuma longa powder.

Abstract translation: 本发明涉及含有用于治疗酒精性肝损伤的发酵姜黄粉的组合物。 本发明的发酵姜黄粉是通过使用米曲霉发酵的姜黄发酵材料进行发酵而得到的，对该材料进行灭菌干燥，在酒精性肝损伤模型中显示出强烈的肝损伤控制功能。 该组合物可用于治疗和预防酒精性肝损伤的食物，医疗产品和使用发酵的姜黄粉的外用医药产品。

公开(公告)号：KR1020140046233A

公开(公告)日：2014-04-18

申请号：KR1020120112449

申请日：2012-10-10

Applicant: 한국인스팜(주) ,  전남대학교산학협력단

Inventor： 서은진 ,  유양희 ,  전우진 ,  김용재 ,  오규철 ,  김선오 ,  이유현

IPC: A61K36/73 ,  A61K36/738 ,  A61P25/00

CPC classification number: A61K36/738 ,  A23V2200/322 ,  A61K2236/331

Abstract: The present invention relates to a composition comprising an extract of Rosa rugosa stem and leaves and, more specifically, to a pharmaceutical composition and a functional health food for suppressing, preventing, and alleviating stress-related diseases caused by a lack of sleep which comprises a powder or an extract obtainable by extracting and concentrating Rosa rugosa stem and leaves by using various solvents. The extract of Rosa rugosa stem and leaves according to the present invention is confirmed to have excellent effects for increasing survival rate, reducing drowsing, reducing cortisol content, and protecting nerve cells against sleep deprivation in rats.

Abstract translation: 本发明涉及一种组合物，其包含罗莎蔷薇茎和叶的提取物，更具体地涉及用于抑制，预防和减轻由睡眠不足引起的与压力有关的疾病的药物组合物和功能保健食品，其包含 粉末或通过使用各种溶剂提取和浓缩罗莎蔷薇茎叶而获得的提取物。 确认本发明的罗莎芦苇提取物对提高存活率，降低呕吐，降低皮质醇含量，保护神经细胞免受大鼠睡眠剥夺的作用具有优异的效果。