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公开(公告)号：KR1020130060027A
公开(公告)日：2013-06-07
申请号：KR1020110126305
申请日：2011-11-29
Applicant: 포항공과대학교 산학협력단
CPC classification number: G01Q70/14 , G01Q60/08 , G01Q70/18 , G01R1/06727
Abstract: PURPOSE: A cantilever for MFM(Magnetic Force Microscopy) and a manufacturing method thereof are provided to offer resolution entered into one or more magnetic force elements. CONSTITUTION: A cantilever(1) for MFM includes a body(5), and a probe(10) formed at the end of the body. The probe includes a magnetic force element combined with the Dendron with a bonding agent and with a surface based on the Dendron.
Abstract translation: 目的：提供用于MFM（磁力显微镜）的悬臂及其制造方法，以提供进入一个或多个磁力元件的分辨率。 构成：用于MFM的悬臂（1）包括主体（5）和形成在身体末端的探针（10）。 探头包括与Dendron与粘合剂组合的磁力元件，并具有基于Dendron的表面。
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公开(公告)号：KR1020100008022A
公开(公告)日：2010-01-25
申请号：KR1020080068395
申请日：2008-07-15
Applicant: 포항공과대학교 산학협력단
Abstract: PURPOSE: A method for manufacturing a molecule monolayer including an alkyne compound is provided to form a molecule monolayer of an alkyne compound in a minute and precise level from a furoxan monolayer on the surface of a substrate using extreme ultraviolet rays. CONSTITUTION: A method for manufacturing a molecule monolayer including an alkyne compound comprises: a molecular layer formation step that forms a furoxan monolayer on the surface of a substrate; and a light irradiation step that irradiates extreme ultraviolet rays to the furoxan monolayer formed in the sample preparation step. A method for forming a molecule monolayer comprises the steps of: washing a substrate for forming the furoxan monolayer; forming an APDES((3-aminoproryl)diethoxymethylsilane) molecular monolayer on the surface of washed substrate; and forming the furoxan monolayer by reacting the furoxan compound on the APDES molecular monolayer.
Abstract translation: 目的：提供用于制造包含炔化合物的分子单层的方法，以使用极紫外线从基底表面上的呋喃糖单层以微细且精确的水平形成炔化合物的分子单层。 构成：制造包含炔化合物的分子单层的方法包括：分子层形成步骤，在基材表面上形成呋喃糖单层; 以及向样品制备工序中形成的呋喃糖单层照射极紫外线的光照射工序。 形成分子单层的方法包括以下步骤：洗涤形成呋喃糖单层的底物; 在洗涤的底物的表面上形成APDES（（3-氨基环戊基）二乙氧基甲基硅烷）分子单层; 并通过使呋喃糖化合物与APDES分子单层反应形成呋喃糖单层。
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公开(公告)号：KR1020080052587A
公开(公告)日：2008-06-11
申请号：KR1020087006105
申请日：2006-08-14
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6816 , G01Q60/42 , B82Y35/00 , C12Q2565/601 , G01N33/50
Abstract: Biomolecule interaction using an atomic force microscope is provided to analyze ligand-receptor interaction by fixing a ligand at the tip of the atomic force microscope using dendron. A cantilever for an atomic force microscope comprises a main body with a fixed end and a free end. The free end has a surface chemically deformed by dendron. The ends located on a basin of the dendron are coupled to the deformed surface. The end of linear portion of the dendron has become a functional group.
Abstract translation: 提供使用原子力显微镜的生物分子相互作用，通过使用树枝状结构在原子力显微镜的尖端固定配体来分析配体 - 受体相互作用。 原子力显微镜的悬臂包括具有固定端和自由端的主体。 自由端具有通过树枝状化学变形的表面。 位于树突的盆地上的端部与变形的表面相连。 树突的直线部分的末端已经成为一个官能团。
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公开(公告)号：KR101737450B1
公开(公告)日：2017-05-18
申请号：KR1020150175338
申请日：2015-12-09
Applicant: 포항공과대학교 산학협력단
IPC: C12Q1/68
Abstract: 본발명은 (a) 표적마이크로 RNA(miRNA)가포함된생체시료상에상기표적 miRNA에상보적으로결합할수 있는염기서열을포함하는프로브 DNA를접촉시켜 DNA/RNA 혼성화체를인시츄(in-situ) 형성하는단계, 및 (b) 원자간력현미경(AFM)용캔틸레버를통해특정영역의결합힘-지도화를수행하여단일세포내 DNA/RNA 혼성화체의이중나선의존재를검출하고, 공간적분포를분석하는단계를포함하되; 상기캔틸레버는탐침및 상기탐침의표면에고정된하이브리드결합도메인(hybrid binding domain, HBD) 또는이의변이체를포함하는마이크로 RNA의고해상도시각화방법에관한것이다.
Abstract translation: （A）将包含与目标miRNA互补的碱基序列的探针DNA与含有目标微小RNA（miRNA）的生物样品接触，以制备DNA / RNA杂交产物， （b）通过原子力显微镜（AFM）悬臂执行特定区域的结合力映射来检测单个细胞中DNA / RNA杂交体的双螺旋的存在;以及 分析分布; 悬臂涉及包含探针和固定在探针或其变体表面上的杂合结合结构域（HBD）的微RNA的高分辨率可视化方法。
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公开(公告)号：KR1020120119909A
公开(公告)日：2012-10-31
申请号：KR1020127015322
申请日：2009-11-16
Applicant: 포항공과대학교 산학협력단
CPC classification number: C12Q1/6837 , B01J2219/00387 , B01J2219/00509 , B01J2219/00529 , B01J2219/00608 , B01J2219/00612 , B01J2219/00617 , B01J2219/00621 , B01J2219/00626 , B01J2219/00653 , B01J2219/00722 , C40B80/00 , G01Q60/42 , C12Q1/6806 , B82Y30/00 , B82Y35/00 , B82Y40/00 , C12Q2565/601 , C12Q2537/113 , C12Q2533/107
Abstract: PURPOSE: A manufacturing method of oligonucleotide which is surface combined on a solid surface is provided to manufacture one piece of oligonucleotide probe by covalently bonding the non-bonded oligonucleotide. CONSTITUTION: A manufacturing method of oligonucleotide which are surface combined on a solid surface comprises the following steps: contacting a first oligonucleotide with a target oligonucleotide which includes oligonucleotide sequence corresponding to the first oligonucleotide sequence under a condition which is enough for manufacturing oligonucleotide complex; contacting partially mixed oligonucleotide combination with a second oligonucleotide including the oligonucleotide sequence which corresponds with non-mixed part of the target oligonucleotide; and manufacturing oligonucleotide combination which includes the surface combined oligonucleotide. [Reference numerals] (AA) Hybridization; (BB) Leading DNA; (CC) Target DNA
Abstract translation: 目的：提供在固体表面上表面组合的寡核苷酸的制造方法，以通过共价键合非键合的寡核苷酸制造一片寡核苷酸探针。 构成：表面组合在固体表面上的寡核苷酸的制造方法包括以下步骤：在足以制造寡核苷酸复合物的条件下使第一寡核苷酸与包含与第一寡核苷酸序列对应的寡核苷酸序列的靶寡核苷酸接触; 使部分混合的寡核苷酸组合与包含与靶寡核苷酸的非混合部分相对应的寡核苷酸序列的第二寡核苷酸接触; 并制备包含表面结合寡核苷酸的寡核苷酸组合。 （附图标记）（AA）杂交; （BB）领先DNA; （CC）靶DNA
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Patent Agency Ranking
公开(公告)号：KR101742211B1
公开(公告)日：2017-05-31
申请号：KR1020150164100
申请日：2015-11-23
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6837 , C12Q1/6816 , G01Q60/38 , G01Q60/42 , C12Q2522/101 , C12Q2525/207 , C12Q2565/501 , C12Q2565/601
Abstract: 본발명은 DNA와 RNA의이중가닥에특이적으로결합하는하이브리드결합도메인 (hybrid binding domain, HBD)이고정된원자간력현미경의탐침을이용하여무표지의마이크로RNA를초고민감도로검출하는방법및 상기하이브리드결합도메인이고정된원자간력현미경의탐침및 무표지의마이크로 RNA를포함하는정량분석장치에관한것이다.
Abstract translation: 本发明涉及一种方法，用于在所述双链杂交物结合域检测（混合结合结构域，HBD）特异性结合使用静态原子力显微镜的超DNA和RNA的非标记的灵敏度的微RNA的探针，并 以及定量分析装置，其包括固定有杂交结合结构域的原子力显微镜的探针和未标记的微小RNA。
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公开(公告)号：KR101439788B1
公开(公告)日：2014-09-15
申请号：KR1020130099935
申请日：2013-08-22
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단 , 한양대학교 산학협력단
CPC classification number: B82B3/0095 , B01J23/881 , B82Y40/00 , C01B32/158 , C23C14/34 , C23C16/45525 , C25D3/02
Abstract: The present invention relates to a method for manufacturing a metal or metal oxide nanostructure comprising the steps of: forming a silicon pillar structure on one side of a silicon substrate; impregnating the silicon substrate with the silicon pillar structure in a catalytic solution; providing carbon source gas to the impregnated silicon substrate to form a three-dimensional network of a carbon nanotube between the silicon pillars; coating the three-dimensional network of carbon nanotube; and electrochemically depositing metal or metal oxide after coating. According to the present invention, provided is the metal or metal oxide nanostructure based on the three-dimensional carbon nanotube network with a large cross sectional area and a hierarchical structure by depositing by an electrochemical method.
Abstract translation: 本发明涉及一种金属或金属氧化物纳米结构体的制造方法，包括以下步骤：在硅衬底的一侧上形成硅柱结构; 在硅催化溶液中用硅柱结构浸渍硅衬底; 向浸渍的硅衬底提供碳源气体以在硅柱之间形成碳纳米管的三维网络; 涂覆碳纳米管的三维网络; 并在涂覆后电化学沉积金属或金属氧化物。 根据本发明，提供了基于具有大横截面积的三维碳纳米管网络的金属或金属氧化物纳米结构和通过电化学方法沉积的分层结构。
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公开(公告)号：KR101069898B1
公开(公告)日：2011-10-05
申请号：KR1020087006105
申请日：2006-08-14
Applicant: 주식회사 포스코 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6816 , G01Q60/42 , C12Q2565/601
Abstract: 본발명은원자현미경(atomic force microscopy, ATM)용캔틸레버(cantilever)에관한것이다. 상기캔틸레버는고정말단과비고정말단을가진캔틸레버본체, 덴드론(dendron)의분지된부위에있는다수의말단과결합하고덴드론에의해화학적으로변형된표면부위를가진비고정말단, 및관능기화된덴드론의선형부위의말단을포함한다.
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公开(公告)号：KR101027513B1
公开(公告)日：2011-04-06
申请号：KR1020080068395
申请日：2008-07-15
Applicant: 포항공과대학교 산학협력단
Abstract: 본 발명은 퓨록산분자(furoxan molecule)를 이용한 알카인(alkyne)화합물의 단분자막형성방법에 관한 것으로, 본 발명에 따르면 극자외선을 사용하여 극자외선에 의한 퓨록산분자막의 변화를 유도하여 알카인(alkyne)화합물의 단분자막을 국소적으로 기판의 표면상에 형성시킬 수 있기 때문에 선택적으로 미세한 부분에 알카인(alkyne)화합물의 단분자막에 다른 화학분자를 반응시킬 수 있는 기초기술을 제공한다.
퓨록산, 극자외선, 자기조립분자막, 삼중결합-
公开(公告)号：KR1020150071876A
公开(公告)日：2015-06-29
申请号：KR1020130158969
申请日：2013-12-19
Applicant: 엘지전자 주식회사 , 포항공과대학교 산학협력단
CPC classification number: C12Q1/6869 , C12N15/11
Abstract: 본발명은원자힘현미경 (AFM, atomic force microscope)을이용한염기서열분석방법에대한것으로, 특히 AFM용캔틸레버의팁에부착된중합효소및 프라이머와, dNTP가부착된기판상의 dNTP 사이의물리적인힘을통해핵산의염기서열을분석하는것을특징으로한다.
Abstract translation: 本发明涉及使用原子力显微镜（AFM）分析碱基序列的方法。 特别地，该方法被配置为通过聚合酶和与AFM的悬臂末端连接的引物之间的物理力和用dNTP附着的dNTP底物来分析核酸的碱基序列。
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