公开(公告)号：BG65264B1

公开(公告)日：2007-10-31

申请号：BG10456400

申请日：2000-06-27

Applicant: ABBOTT LAB

Inventor： BEUTEL BRUCE ,  SCHURDACK MARK ,  VOORBACH MARTIN ,  BURNS DAVID ,  JOSEPH MARY

IPC: G01N33/48 ,  G01N33/577 ,  A61K39/395 ,  A61K51/10 ,  C07B63/00 ,  C07K16/18 ,  C12N1/21 ,  C12N15/13 ,  G01N33/50 ,  G01N33/543 ,  G01N33/566 ,  G01N33/68 ,  G01N37/00

Abstract: Continuous format high throughput screening (CF-HTS) using at least one porous matrix allows the pharmaceutical industry to simultaneously screen large numbers of chemical entities for a wide range of biological or biochemical activity. In addition, CF-HTS is useful to perform multi-step assays.

公开(公告)号：CA2518443A1

公开(公告)日：2004-09-30

申请号：CA2518443

申请日：2003-03-12

Applicant: ABBOTT LAB

Inventor： HANSEN TODD MATTHEW ,  TUFANO MICHAEL ,  CLARK RICHARD ,  WAGNER ROLF ,  HINMAN MIRA ,  LARSON DANIEL P ,  WEITZBERG MOSHE ,  KALVIN DOUGLAS ,  SANDERS WILLIAM ,  BOSSE TODD D ,  ROSENBERG TERESA ,  DANDLIKER PETER ,  MOTTER CHRISTOPHER ,  MA ZHENKUN ,  ANDERSON DAVID ,  PALAZZO FABIO ,  DAVID CAROLINE ,  COOPER CURT ,  BEUTEL BRUCE ,  GU YU-GUI ,  REHM TAMARA ,  LYNCH LINDA ,  YONG HONG ,  ZHANG TIANYUAN

IPC: A61P31/04 ,  C07D471/04 ,  A61K31/435

Abstract: Antibacterials having formula (I), and salts, prodrugs, and salts of prodrug s thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophylaxis and treatment of bacterial infections using the compounds are disclosed.