公开(公告)号：BG64707B1

公开(公告)日：2005-12-30

申请号：BG10443400

申请日：2000-05-15

Applicant: ABBOTT LAB

Inventor： PHAN LY ,  OR YAT SUN ,  CHU DANIEL ,  PLATTNER JACOB ,  CHEN YAN ,  CLARK RICHARD

IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  A61K31/70

Abstract: The invention relates to novel 2-halo-6-O-substituted ketolide derivatives with the formula to their pharmaceutically acceptable salts having antibacterial activity, to pharmaceutical compositions comprising a therapeutically effective amount of a compound according to the invention in combination with a pharmaceutically acceptable carrier, as well as to the utilization of the compounds or their pharmaceutically acceptable salt for the preparation of a medicament for treating bacterial infections in mammals. The invention also relates to the preparation of the compounds.