公开(公告)号：BG107908A

公开(公告)日：2004-01-30

申请号：BG10790803

申请日：2003-06-13

Applicant: ABBOTT LAB

Inventor： CLAIBORNE AKYO K ,  GWALTNEY II STEPHEN L ,  HASVOLD LISA A ,  LI QUN ,  LI TOMGMEI ,  LIN NAN-HORNG ,  MANTEI ROBERT A ,  ROCKWAY TODD W ,  SHAM HING L ,  SULLIVAN GERARD M ,  TONG YUNSONG ,  WANG GARY T ,  WANG LE ,  WANG XILU ,  WANG WEIBO

IPC: A61K31/4164 ,  A61K31/4178 ,  A61K31/426 ,  A61K31/4439 ,  A61K31/4709 ,  A61P35/00 ,  A61P43/00 ,  C07D233/54 ,  C07D233/64 ,  C07D277/20 ,  C07D277/30 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12

Abstract: Substituted imidazoles and thiazoles having formula are used for inhibiting farnesyltransferase. Also disclosed are farnesylransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient. 10 claims