公开(公告)号：DE60118955T2

公开(公告)日：2007-01-04

申请号：DE60118955

申请日：2001-11-30

Applicant: ABBOTT LAB

Inventor： CLAIBORNE K ,  GWALTNEY L ,  HASVOLD A ,  LI QUN ,  LI TOMGMEI ,  LIN NAN-HORNG ,  MANTEI A ,  ROCKWAY W ,  SHAM L ,  SULLIVAN M ,  TONG YUNSONG ,  WANG T ,  WANG LE ,  WANG XILU ,  WANG WEIBO

IPC: C07D233/64 ,  A61K31/4164 ,  A61K31/4178 ,  A61K31/426 ,  A61K31/4439 ,  A61K31/4709 ,  A61P35/00 ,  A61P43/00 ,  C07D233/54 ,  C07D277/20 ,  C07D277/30 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12

Abstract: Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.

公开(公告)号：DE60118955D1

公开(公告)日：2006-05-24

申请号：DE60118955

申请日：2001-11-30

Applicant: ABBOTT LAB

Inventor： CLAIBORNE K ,  GWALTNEY L ,  HASVOLD A ,  LI QUN ,  LI TOMGMEI ,  LIN NAN-HORNG ,  MANTEI A ,  ROCKWAY W ,  SHAM L ,  SULLIVAN M ,  TONG YUNSONG ,  WANG T ,  WANG LE ,  WANG XILU ,  WANG WEIBO

IPC: C07D233/64 ,  A61K31/4164 ,  A61K31/4178 ,  A61K31/426 ,  A61K31/4439 ,  A61K31/4709 ,  A61P35/00 ,  A61P43/00 ,  C07D233/54 ,  C07D277/20 ,  C07D277/30 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12

Abstract: Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.