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公开(公告)号：DE60008527T2
公开(公告)日：2004-12-23
申请号：DE60008527
申请日：2000-05-26
Applicant: ABBOTT LAB
Inventor： QUN LI , SHAM HING , STEINER A , GWALTNEY L , BARR J , IMADE M , ROSENBERG SAUL , WOODS W
IPC: A61K31/10 , A61K31/136 , A61K31/167 , A61K31/18 , A61K31/255 , A61K31/357 , A61K31/403 , A61K31/404 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/44 , A61K31/47 , A61K31/63 , A61P35/00 , A61P43/00 , C07C235/56 , C07C309/73 , C07C309/75 , C07C309/76 , C07C311/21 , C07C311/29 , C07C311/44 , C07C311/46 , C07C317/18 , C07C317/22 , C07C317/28 , C07C317/36 , C07C317/46 , C07C323/20 , C07C323/29 , C07D209/08 , C07D209/30 , C07D209/32 , C07D213/69 , C07D213/70 , C07D213/71 , C07D215/38 , C07D231/56 , C07D235/04 , C07D235/06 , C07D235/08 , C07D319/18 , C07D403/12
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公开(公告)号：DE60008527D1
公开(公告)日：2004-04-01
申请号：DE60008527
申请日：2000-05-26
Applicant: ABBOTT LAB
Inventor： QUN LI , SHAM HING , STEINER A , GWALTNEY L , BARR J , IMADE M , ROSENBERG SAUL , WOODS W
IPC: A61K31/10 , A61K31/136 , A61K31/167 , A61K31/18 , A61K31/255 , A61K31/357 , A61K31/403 , A61K31/404 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/44 , A61K31/47 , A61K31/63 , A61P35/00 , A61P43/00 , C07C235/56 , C07C309/73 , C07C309/75 , C07C309/76 , C07C311/21 , C07C311/29 , C07C311/44 , C07C311/46 , C07C317/18 , C07C317/22 , C07C317/28 , C07C317/36 , C07C317/46 , C07C323/20 , C07C323/29 , C07D209/08 , C07D209/30 , C07D209/32 , C07D213/69 , C07D213/70 , C07D213/71 , C07D215/38 , C07D231/56 , C07D235/04 , C07D235/06 , C07D235/08 , C07D319/18 , C07D403/12
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公开(公告)号：DE60118955T2
公开(公告)日：2007-01-04
申请号：DE60118955
申请日：2001-11-30
Applicant: ABBOTT LAB
Inventor： CLAIBORNE K , GWALTNEY L , HASVOLD A , LI QUN , LI TOMGMEI , LIN NAN-HORNG , MANTEI A , ROCKWAY W , SHAM L , SULLIVAN M , TONG YUNSONG , WANG T , WANG LE , WANG XILU , WANG WEIBO
IPC: C07D233/64 , A61K31/4164 , A61K31/4178 , A61K31/426 , A61K31/4439 , A61K31/4709 , A61P35/00 , A61P43/00 , C07D233/54 , C07D277/20 , C07D277/30 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.
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公开(公告)号：DE60118955D1
公开(公告)日：2006-05-24
申请号：DE60118955
申请日：2001-11-30
Applicant: ABBOTT LAB
Inventor： CLAIBORNE K , GWALTNEY L , HASVOLD A , LI QUN , LI TOMGMEI , LIN NAN-HORNG , MANTEI A , ROCKWAY W , SHAM L , SULLIVAN M , TONG YUNSONG , WANG T , WANG LE , WANG XILU , WANG WEIBO
IPC: C07D233/64 , A61K31/4164 , A61K31/4178 , A61K31/426 , A61K31/4439 , A61K31/4709 , A61P35/00 , A61P43/00 , C07D233/54 , C07D277/20 , C07D277/30 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.
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