公开(公告)号：JP2012137501A

公开(公告)日：2012-07-19

申请号：JP2012083533

申请日：2012-04-02

Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

Inventor： SAFAR SCOTT G ,  CHARLES M GEARLITZ ,  HERCHENBACH STEPHEN L ,  CHADWICK M DANN ,  MCDOWELL LARRY L

IPC: C12N15/09 ,  G01N35/02 ,  B01L3/14 ,  B01L9/06 ,  B03C1/00 ,  B03C1/02 ,  C12M1/00 ,  C12M1/26 ,  G01N35/00 ,  G01N35/10

CPC classification number: B01L3/5085 ,  B01D35/06 ,  B01L3/5082 ,  B01L9/06 ,  B01L2300/0848 ,  B03C1/02 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N35/0098 ,  G01N2035/00564 ,  G01N2035/103 ,  Y10S436/809 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/25375 ,  Y10T436/2575

Abstract: PROBLEM TO BE SOLVED: To provide a structure and method for handling magnetic particles in biological assays.SOLUTION: A magnetic handling structure 1a comprising a retractable magnet 4 and a probe 3 for manipulation of magnetic particles in biological samples and methods of handling magnetic particles in biological samples are provided.

Abstract translation: 要解决的问题：提供在生物测定中处理磁性颗粒的结构和方法。 解决方案：提供一种磁性处理结构1a，其包括可伸缩磁体4和用于操纵生物样品中的磁性颗粒的探针3和处理生物样品中的磁性颗粒的方法。 版权所有（C）2012，JPO＆INPIT

公开(公告)号：JP2009229470A

公开(公告)日：2009-10-08

申请号：JP2009160190

申请日：2009-07-06

Applicant: Abbott Lab ,  アボット・ラボラトリーズAbbott Laboratories

Inventor： SAFAR SCOTT G ,  GALITZ CHARLES M ,  HERCHENBACH STEPHEN L ,  DUNN CHADWICK M ,  MCDOWELL LARRY L

IPC: C12N15/09 ,  G01N35/02 ,  B01L3/14 ,  B01L9/06 ,  B03C1/00 ,  B03C1/02 ,  C12M1/00 ,  C12M1/26 ,  G01N35/00 ,  G01N35/10

CPC classification number: B01L3/5085 ,  B01D35/06 ,  B01L3/5082 ,  B01L9/06 ,  B01L2300/0848 ,  B03C1/02 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N35/0098 ,  G01N2035/00564 ,  G01N2035/103 ,  Y10S436/809 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/25375 ,  Y10T436/2575

Abstract: PROBLEM TO BE SOLVED: To provide a structure and method for handling magnetic particles in bioassay. SOLUTION: A magnetic handling structure 1a includes a retractable magnet 4 and a probe 3 for the manipulation of magnetic particles in a biological sample, and a method is provided for handling the magnetic particles in the biological sample. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供在生物测定中处理磁性颗粒的结构和方法。 解决方案：磁性处理结构1a包括可伸缩磁体4和用于操纵生物样品中的磁性颗粒的探针3，并且提供了用于处理生物样品中的磁性颗粒的方法。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：EP1499415A4

公开(公告)日：2009-10-28

申请号：EP03719947

申请日：2003-04-25

Applicant: ABBOTT LAB

Inventor： SAFAR SCOTT G ,  GALITZ CHARLES M ,  HERCHENBACH STEPHEN L ,  DUNN CHADWICK M ,  MCDOWELL LARRY L

IPC: C12N15/09 ,  B01L3/14 ,  B01L9/06 ,  B03C1/00 ,  B03C1/02 ,  C12M1/00 ,  C12M1/26 ,  G01N35/00 ,  B01D35/06 ,  G01N33/553 ,  G01N35/02 ,  G01N35/10

CPC classification number: B01L3/5085 ,  B01D35/06 ,  B01L3/5082 ,  B01L9/06 ,  B01L2300/0848 ,  B03C1/02 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N35/0098 ,  G01N2035/00564 ,  G01N2035/103 ,  Y10S436/809 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/25375 ,  Y10T436/2575

Abstract: Magnetic handling structure (1a) comprising a retractable magnet (4) and a probe (3) for the manipulation of magnetic particles in biological samples and methods of handling magnetic particles in biological samples.

Abstract translation: 磁性处理结构（1a）包括用于操纵生物样品中的磁性颗粒的可伸缩磁体（4）和探针（3）和处理生物样品中的磁性颗粒的方法。

公开(公告)号：CA2483445C

公开(公告)日：2011-04-19

申请号：CA2483445

申请日：2003-04-25

Applicant: ABBOTT LAB

Inventor： SAFAR SCOTT G ,  GALITZ CHARLES M ,  HERCHENBACH STEPHEN L ,  DUNN CHADWICK M ,  MCDOWELL LARRY L

IPC: B01D35/06 ,  C12N15/09 ,  B01L3/14 ,  B01L9/06 ,  B03C1/00 ,  B03C1/02 ,  C12M1/00 ,  C12M1/26 ,  G01N33/553 ,  G01N35/00 ,  G01N35/02

Abstract: Magnetic handling structure (1a) comprising a retractable magnet (4) and a probe (3) for the manipulation of magnetic particles in biological samples and methods of handling magnetic particles in biological samples.

公开(公告)号：CA2483445A1

公开(公告)日：2003-11-06

申请号：CA2483445

申请日：2003-04-25

Applicant: ABBOTT LAB

Inventor： GALITZ CHARLES M ,  MCDOWELL LARRY L ,  DUNN CHADWICK M ,  HERCHENBACH STEPHEN L ,  SAFAR SCOTT G

IPC: C12N15/09 ,  B01L3/14 ,  B01L9/06 ,  B03C1/00 ,  B03C1/02 ,  C12M1/00 ,  C12M1/26 ,  G01N35/00 ,  B01D35/06 ,  G01N35/02 ,  G01N33/553

Abstract: Magnetic handling structure (1a) comprising a retractable magnet (4) and a probe (3) for the manipulation of magnetic particles in biological samples a nd methods of handling magnetic particles in biological samples.

公开(公告)号：CA2341538A1

公开(公告)日：2000-03-09

申请号：CA2341538

申请日：1999-08-27

Applicant: ABBOTT LAB

Inventor： PEZZANITI JOSEPH L ,  MCDOWELL LARRY L ,  JENG TZYY-WEN ,  SHAIN ERIC B ,  OOSTA GARY M

IPC: G01N21/64 ,  G01N21/05 ,  G01N21/27 ,  G01N21/33 ,  G01N21/35 ,  G01N21/41 ,  G01N21/65 ,  G01N33/483 ,  G01N33/493 ,  B01L3/14

Abstract: Apparatus and method for determining at least one parameter, e.g., concentration, of at least one analyte, e.g., urea, of a biological sample, e.g., urine. A biological sample particularly suitable for the apparatus and method of this invention is urine. In general, spectroscopic measurements ca n be used to quantify the concentrations of one or more analytes in a biologic al sample. In order to obtain concentration values of certain analytes, such as hemoglobin and bilirubin, visible light absorption spectroscopy can be used. In order to obtain concentration values of other analytes, such as urea, creatinine, glucose, ketones, and protein, infrared light absorption spectroscopy can be used. The apparatus and method of this invention utilize one or more mathematical techniques to improve the accuracy of measurement o f parameters of analytes in a biological sample. The invention also provides a n apparatus and method for measuring the refractive index of a sample of biological fluid while making spectroscopic measurements substantially simultaneously.