公开(公告)号：WO2006122250A3

公开(公告)日：2007-03-29

申请号：PCT/US2006018256

申请日：2006-05-10

Applicant: ABBOTT LAB ,  GOMTSYAN ARTHUR ,  PERNER RICHARD ,  KOENIG JOHN ,  HSU MARGARET CHI-PING ,  FERNANDO DILINI ,  LEE CHIH-HUNG

Inventor： GOMTSYAN ARTHUR ,  PERNER RICHARD ,  KOENIG JOHN ,  HSU MARGARET CHI-PING ,  FERNANDO DILINI ,  LEE CHIH-HUNG

IPC: C07D263/48 ,  A61K31/421 ,  A61P29/00

CPC classification number: C07D263/48

Abstract: The present invention is directed to compounds of formula (I) (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.

Abstract translation: 本发明涉及式（I）（I）的化合物，其中变量W，X，Y，D，A，n，R 1，R 2和R 9如说明书中所定义。

公开(公告)号：CA2608091A1

公开(公告)日：2006-11-16

申请号：CA2608091

申请日：2006-05-10

Applicant: ABBOTT LAB

Inventor： KOENIG JOHN ,  FERNANDO DILINI ,  LEE CHIH-HUNG ,  HSU MARGARET CHI-PING ,  PERNER RICHARD ,  GOMTSYAN ARTHUR

IPC: C07D263/48 ,  A61K31/421 ,  A61P29/00

Abstract: The present invention is directed to compounds of formula (I) (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.

公开(公告)号：AT526320T

公开(公告)日：2011-10-15

申请号：AT06759574

申请日：2006-05-10

Applicant: ABBOTT LAB

Inventor： GOMTSYAN ARTHUR ,  PERNER RICHARD ,  KOENIG JOHN ,  HSU MARGARET CHI-PING ,  FERNANDO DILINI ,  LEE CHIH-HUNG

IPC: C07D263/48 ,  A61K31/421 ,  A61P29/00

Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.

公开(公告)号：AU2006243987A1

公开(公告)日：2006-11-16

申请号：AU2006243987

申请日：2006-05-10

Applicant: ABBOTT LAB

Inventor： KOENIG JOHN ,  LEE CHIH-HUNG ,  HSU MARGARET CHI-PING ,  GOMTSYAN ARTHUR ,  FERNANDO DILINI ,  PERNER RICHARD

IPC: C07D263/48 ,  A61K31/421 ,  A61P29/00

Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.

公开(公告)号：MX2007014048A

公开(公告)日：2008-02-05

申请号：MX2007014048

申请日：2006-05-10

Applicant: ABBOTT LAB

Inventor： GOMTSYAN ARTHUR ,  LEE CHIH-HUNG ,  PERNER RICHARD ,  KOENIG JOHN ,  HSU MARGARET CHI-PING ,  FERNANDO DILINI

IPC: C07D263/48 ,  A61K31/421 ,  A61P29/00

Abstract: La presente invencion se dirige a los compuestos de la formula (I) en donde los variables, W, X, Y, D, A, n, R1, R2 y R9 son como se definen en la descripcion.

公开(公告)号：DE69025472D1

公开(公告)日：1996-03-28

申请号：DE69025472

申请日：1990-05-22

Applicant: ABBOTT LAB

Inventor： SCHOENLEBER ROBERT ,  KEBABIAN JOHN ,  MARTIN YVONNE ,  DENINNO MICHAEL ,  PERNER RICHARD ,  STOUT DAVID ,  HSIAO CHI-NUNG ,  DIDOMENICO STANLEY ,  DEBERNARDIS JOHN ,  BASHA FATIMA ,  MEYER MICHEAL ,  DE BISWANATH ,  EHRLICH PAUL ,  CAMPBELL JAMES ,  MORTON HOWARD ,  LIJEWSKI LINDA

IPC: A61K31/13 ,  A61K31/135 ,  A61K31/16 ,  A61K31/335 ,  A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61K38/00 ,  A61P9/00 ,  A61P25/00 ,  A61P25/18 ,  A61P25/30 ,  C07C41/02 ,  C07C215/48 ,  C07C215/64 ,  C07C217/56 ,  C07C217/74 ,  C07C219/28 ,  C07C233/18 ,  C07C237/08 ,  C07C271/16 ,  C07C271/44 ,  C07C309/65 ,  C07C323/60 ,  C07D207/08 ,  C07D209/08 ,  C07D209/62 ,  C07D221/06 ,  C07D221/10 ,  C07D221/20 ,  C07D311/76 ,  C07D311/78 ,  C07D311/96 ,  C07D313/08 ,  C07D405/04 ,  C07D405/06 ,  C07D405/12 ,  C07D407/04 ,  C07D407/12 ,  C07D493/10 ,  C07K5/06 ,  C07D409/04 ,  C07D311/74 ,  C07D487/00 ,  C07D209/56 ,  C07D211/00 ,  C07C69/76 ,  A01N43/32 ,  A01N43/16 ,  A01N43/42 ,  A01N43/62

Abstract: Novel compounds which are selective dopamine agonists are useful for treating disorders characterized by abnormal dopamine levels, such as Parkinson's Disease, as well as cardiovascular disorders.

公开(公告)号：NZ563200A

公开(公告)日：2011-04-29

申请号：NZ56320006

申请日：2006-05-10

Applicant: ABBOTT LAB

Inventor： GOMTSYAN ARTHUR ,  PERNER RICHARD ,  KOENIG JOHN ,  HSU MARGARET CHI-PING ,  FERNANDO DILINI ,  LEE CHIH-HUNG

IPC: C07D263/48 ,  A61K31/421 ,  A61P29/00 ,  C07D233/66 ,  C07D233/70 ,  C07D233/88 ,  C07D263/34 ,  C07D263/38 ,  C07D277/32 ,  C07D277/34 ,  C07D277/38

Abstract: Disclosed are substituted imidazole and oxazole compounds of formula (I), wherein A is O or -N(R3), D is O or -N(R4), and the remaining substituents are as defined in the specification, and compositions comprising them. The compounds are useful for treating disorders caused by or exacerbated by vanilloid receptor activity, such as pain, bladder overactivity, and urinary incontinence.

公开(公告)号：BRPI0608810A2

公开(公告)日：2010-01-26

申请号：BRPI0608810

申请日：2006-05-10

Applicant: ABBOTT LAB

Inventor： GOMTSYAN ARTHUR ,  PERNER RICHARD ,  HSU MARGARET CHI-PING ,  FERNANDO DILINI ,  LEE CHIH-HUNG ,  KOENIG JOHN

IPC: C07D263/48 ,  A61K31/421 ,  A61P29/00

Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.

公开(公告)号：HK1114837A1

公开(公告)日：2008-11-14

申请号：HK08104710

申请日：2008-04-28

Applicant: ABBOTT LAB

Inventor： GOMTSYAN ARTHUR ,  PERNER RICHARD ,  KOENIG JOHN ,  HSU MARGARET CHI-PING ,  FERNANDO DILINI ,  LEE CHIH-HUNG

IPC: A61K20060101 ,  A61P20060101 ,  C07D20060101

Abstract: The present invention is directed to compounds of formula (I) wherein variables W, X, Y, D, A, n, R1, R2 and R9 are as defined in the description.

公开(公告)号：AT553093T

公开(公告)日：2012-04-15

申请号：AT07814410

申请日：2007-08-24

Applicant: ABBOTT LAB

Inventor： LEE CHIH-HUNG ,  BROWN BRIAN ,  PERNER RICHARD ,  DARBYSHIRE JOHN

IPC: C07D231/56 ,  A61K31/416 ,  A61P25/00

Abstract: Compounds of formula (I) wherein R3, R7, R9 and L are defined in the description are TRPV1 antagonists that exhibit low inhibitory activity against CYP3A4. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.