公开(公告)号：WO0220568A3

公开(公告)日：2002-09-26

申请号：PCT/US0127410

申请日：2001-09-04

Applicant: ABBOTT LAB

Inventor： FESIK STEPHEN W ,  MEADOWS ROBERT P ,  JOSEPH MARY K ,  OLEJNICZAK EDWARD T ,  PETROS ANDREW M ,  NETTESHEIM DAVID G ,  SWIFT KERRY M ,  MATAYOSHI EDMUND ,  ZHANG HAICHAO

IPC: C07K14/47 ,  G01N33/68

CPC classification number: C07K14/4702

Abstract: The present invention relates to peptides derived from the wild-type human Bad peptide which bind to a member of the Bcl-2 family of proteins. The peptides of the present invention can be used in an assay to identify candidate substances which induce or promote apoptosis in cells.

Abstract translation: 本发明涉及衍生自与蛋白质Bcl-2家族成员结合的野生型人Bad肽的肽。 本发明的肽可用于测定诱导或促进细胞凋亡的候选物质。