公开(公告)号：EP1131322A2

公开(公告)日：2001-09-12

申请号：EP99970991.8

申请日：1999-10-28

Applicant: ABBOTT LABORATORIES

Inventor： CARROLL, William, A. ,  AGRIOS, Konstantinos, A. ,  BASHA, Fatima, Z. ,  CHEN, Yiyuan ,  KORT, Michael, E. ,  KYM, Philip, R. ,  TANG, Rui ,  TURNER, Sean, C. ,  YI, Lin

IPC: C07D471/00 ,  C07D491/04 ,  A61K31/435

CPC classification number: C07D471/04 ,  C07D471/14 ,  C07D491/04 ,  C07D491/14 ,  C07D495/14

Abstract: Compounds having formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

公开(公告)号：EP1278746A2

公开(公告)日：2003-01-29

申请号：EP01934990.1

申请日：2001-05-02

Applicant: Abbott Laboratories

Inventor： CARROLL, William A. ,  AGRIOS, Konstantinos A. ,  BASHA, Fatima Z. ,  CHEN, Yiyuan ,  KORT, Michael E. ,  KYM, Philip R. ,  TANG, Rui ,  TURNER, Sean C. ,  YI, Lin

IPC: C07D471/14 ,  A61K31/4353 ,  A61P15/00 ,  A61P21/00 ,  C07D471/04 ,  C07D491/048 ,  C07D495/14 ,  C07D491/056

CPC classification number: C07D471/04 ,  C07C45/00 ,  C07C45/298 ,  C07C45/30 ,  C07C45/63 ,  C07C205/44 ,  C07D471/14 ,  C07D491/04 ,  C07D491/14 ,  C07D495/14 ,  C07C47/55

Abstract: Compounds having the formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

公开(公告)号：EP1194429A1

公开(公告)日：2002-04-10

申请号：EP00941678.5

申请日：2000-06-23

Applicant: Abbott Laboratories

Inventor： CARROLL, William, A. ,  CHEN, Yiyuan ,  HOLLADAY, Mark, W. ,  KORT, Michael, E. ,  KYM, Philip, R. ,  SULLIVAN, James, P. ,  TANG, Rui ,  YI, Lin ,  ZHANG, Henry, Q.

IPC: C07D495/04 ,  C07D215/36 ,  C07D221/04 ,  A61K31/44

CPC classification number: C07D221/04 ,  C07C45/00 ,  C07C45/298 ,  C07C45/41 ,  C07C45/63 ,  C07C45/71 ,  C07C205/44 ,  C07D215/36 ,  C07D495/04 ,  C07D495/14 ,  C07C47/565 ,  C07C47/55 ,  C07C49/753

Abstract: Compounds having formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

公开(公告)号：EP1194429B1

公开(公告)日：2005-03-30

申请号：EP00941678.5

申请日：2000-06-23

Applicant: Abbott Laboratories

Inventor： CARROLL, William, A. ,  CHEN, Yiyuan ,  HOLLADAY, Mark, W. ,  KORT, Michael, E. ,  KYM, Philip, R. ,  SULLIVAN, James, P. ,  TANG, Rui ,  YI, Lin ,  ZHANG, Henry, Q.

IPC: C07D495/04 ,  C07D215/36 ,  C07D221/04 ,  A61K31/44

CPC classification number: C07D221/04 ,  C07C45/00 ,  C07C45/298 ,  C07C45/41 ,  C07C45/63 ,  C07C45/71 ,  C07C205/44 ,  C07D215/36 ,  C07D495/04 ,  C07D495/14 ,  C07C47/565 ,  C07C47/55 ,  C07C49/753

Abstract: Compounds having formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

Abstract translation: 具有式（I）的化合物可用于治疗通过钾通道开放剂预防或改善的疾病。 还公开了钾通道开放组合物和在哺乳动物中打开钾通道的方法。

公开(公告)号：EP1075466A1

公开(公告)日：2001-02-14

申请号：EP00914832.1

申请日：2000-03-06

Applicant: Abbott Laboratories

Inventor： CARROLL, William A. ,  CHEN, Yiyuan ,  DRIZIN, Irene ,  KERWIN, James, F. ,  MOORE, Jimmie, L.

IPC: C07D211/82 ,  C07D215/20 ,  C07D211/90 ,  A61K31/473

CPC classification number: C07D221/04 ,  C07C45/298 ,  C07D221/06 ,  C07C47/55

Abstract: Compounds of formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.