Abstract:
PROBLEM TO BE SOLVED: To improve a function of an electro spray device disposed so that a spray needle and an ion extraction interface become orthogonal to each other. SOLUTION: An interface axis 122 is disposed in a relationship so as to cross a spray nozzle axis 124, an angle defined between the nozzle axis 124 and the interface axis 122 are set from around 75 ° and around 105 °. An interface 106 is possible to operate to accept a voltage from an interface power source, and an auxiliary electrode 140 can operate for accepting a voltage from an auxiliary power source. The electrode 140 can operate, to regulate electric field at an outlet orifice and disposed in a relationship possible to operate against the orifice. The electro spray device can operate to define an ion passage, through which ions on their ways from the orifice to an inlet are passed and the electrode 140 is disposed outside the ion passage. COPYRIGHT: (C)2005,JPO&NCIPI
Abstract:
PROBLEM TO BE SOLVED: To provide an ion source without requiring a help of air pressure at a time of generating atomization of aerosol. SOLUTION: The ion source is equipped with (a) a first ion spray emitter to generate ion, (b) a conduit adjoining the first ion spray emitter and having an opening designed to accept ions from the first ion spray emitter, (c) a first electrode adjoining the conduit and orienting ions from the first ion spray emitter towards the opening of the capillary tube, and (d) a conduit electrode orienting ions to the conduit. COPYRIGHT: (C)2006,JPO&NCIPI
Abstract:
PROBLEM TO BE SOLVED: To provide a liquid chromatography device capable of functioning as an independent unit and combining with arbitrary desired devices. SOLUTION: In the chromatography device equipped with liquid chromatography chip, a spray nose loaded on the chromatography chip is excluded. In other word, analytical objects are not led to the spray but to a port demarcated by chromatography chip directly or indirectly after passing through a analytical column specified with a chromatography chip. The port is linked fluidically with a conduit pipe and the conduit pipe is connected with the other device. In such a formation, the chromatography chip can perform flexible or widely applicable interconnection with the other device. COPYRIGHT: (C)2007,JPO&INPIT
Abstract:
The invention provides an analytical system having a separating system and a liquid chromatography chip. The liquid chromatography chip has an emitter that includes a material that prevents charge buildup on the emitter surface. Methods of using the analytical system, chip and emitter are also disclosed.
Abstract:
An apparatus and method for generating analyte ions from a sample. An ion generating device is provided having a chamber with an outlet and a surface having a material and means for applying a high velocity gas flow through the chamber toward the outlet such that charged particles are produced by physical interaction between the high velocity gas and the material. The charged particles then induce the generation of primary ions by interaction with molecules of the high velocity gas. The primary ions are emitted from the outlet of the ion generating device toward a sample-bearing surface and analyte ions are generated by impact of the primary ions on the analyte sample on the surface.
Abstract:
Electrospray apparatus, includes: a nozzle providing an exit orifice (130), an entrance orifice, and a passage (126) extending from the entrance orifice to the exit orifice (130), the nozzle defining a nozzle axis (124); an interface providing an inlet (112), an outlet, and a passage extending from the inlet to the outlet, the interface providing an interface axis(122); the interface disposed such that the inlet (112) is adjacent the exit orifice (130) and the interface axis (122) is in transverse relation to the nozzle axis (124); wherein an angle formed between the nozzle axis (124) and the interface axis (122) is between about 75 degrees and about 105 degrees, the interface operable to receive a voltage from an interface voltage source; an auxiliary electrode (140) operable to receive a voltage from an auxiliary voltage source (132), and to modulate an electric field at the exit orifice (130), the electrospray apparatus being operable to define an ion pathway followed by ions enroute from the exit orifice to the inlet, the auxiliary electrode (140) being disposed outside the ion pathway. The auxiliary electrode (140) may be a disk electrode, a pin electrode or an L-shaped electrode. A lumen (110) may supply a counterflow of drying gas (136).
Abstract:
An inlet receives the liquid sample, the inlet being further connected to a tubular first chamber and defining a nozzle on one end and a first pump attached to controllably move the liquid sample through the tubular first chamber in a liquid stream and out of the nozzle. A pneumatic nebuliser downstream from the inlet is coupled with the first chamber. An annular second chamber surrounds the first chamber and both the first and second chambers extending laterally about the same centreline, the second chamber defining a nozzle on one end at a point in close proximity to the nozzle end of the first chamber. A gas flow introduction device is attached to the second chamber. A gas is introduced in a manner so the gas is caused to flow in the second chamber parallel to the flow of liquid sample stream in the first chamber. A second pump is attached to the second chamber to control velocity of the gas relative to the liquid sample flow in the first chamber. A nozzle device is formed in and by the nebuliser housing through the gas and the liquid sample flow and through which point, as a result of the velocity of the gas and liquid and the physical interactions between gas and liquid, ions are created and dispersed into a collecting chamber.