-
1.发明专利
公开(公告)号：JPH11322585A
公开(公告)日：1999-11-24
申请号：JP7868099
申请日：1999-03-23
Applicant: BASF AG
Inventor： KOTHRADE STEPHAN DR , BERNDL GUNTHER , SIMON DIRK , SANNER AXEL DR
Abstract: PROBLEM TO BE SOLVED: To produce the subject dosage form producible by melt extrusion and capable of slowly releasing an agent by using a water swellable graft copolymer as a high-molecular weight binder. SOLUTION: When (A) at least one kind of a high-molecular weight binder, (B) at least one kind of agent and, as necessary, (C) a usual additive are mixed and formed under the formation of a plastic mixture, a water swellable graft copolymer or a mixture thereof is used as the ingredient A. The amounts of the formulated ingredients A and B based on the total weight of the dosage form are preferably 10-100 wt.%, more preferably 40-99.9 wt.% of the ingredient A and preferably 0-90 wt.%, more preferably 0.1-60 wt.% of the ingredient B.
-
公开(公告)号：ES2187457T3
公开(公告)日：2003-06-16
申请号：ES00916925
申请日：2000-03-10
Applicant: BASF AG
Inventor： BERNDL GUNTHER , REINHOLD ULRICH , SIMON DIRK , LEHMANN STEPHAN
-
公开(公告)号：DE19911097A1
公开(公告)日：2000-09-14
申请号：DE19911097
申请日：1999-03-12
Applicant: BASF AG
Inventor： BERNDL GUNTHER , REINHOLD ULRICH , SIMON DIRK , LEHMANN STEPHAN
IPC: A01N25/08 , A01N25/10 , A61K8/73 , A61K8/86 , A61K9/20 , A61K9/22 , A61K31/192 , A61K31/565 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/40 , A61K47/48 , A61Q19/00 , C08B37/16 , A01N25/34 , A23L1/03 , A61K7/00 , A61K31/715 , B01J2/00
Abstract: The invention relates to a method for producing solid dosage forms containing at least one physiologically compatible polymer binding agent, at least one active agent and at least one cyclodextrin as components. According to the method, the components are mixed and plasticised at a temperature below 220 DEG C, without the addition of a solvent. The plastic mixture obtained is shaped into the dosage form. The invention also relates to the dosage forms obtained by said method.
-
公开(公告)号：CA2367020C
公开(公告)日：2008-12-16
申请号：CA2367020
申请日：2000-03-10
Applicant: BASF AG
Inventor： LEHMANN STEPHAN , SIMON DIRK , BERNDL GUNTHER , REINHOLD ULRICH
IPC: A61K9/20 , A01N25/08 , A01N25/10 , A61K8/73 , A61K8/86 , A61K9/22 , A61K31/192 , A61K31/565 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/40 , A61K47/48 , A61Q19/00
Abstract: The invention relates to a method for producing solid dosage forms containin g at least one physiologically compatible polymer binding agent, at least one active agent and at least one cyclodextrin as components . According to the method, the components are mixed and plasticised at a temperature below 220 .degree.C, without the addition of a solvent. The plastic mixture obtained is shaped into the dosage form. The invention also relates to the dosage forms obtained by said method.
-
公开(公告)号：DE59909717D1
公开(公告)日：2004-07-22
申请号：DE59909717
申请日：1999-03-22
Applicant: BASF AG
Inventor： KOTHRADE STEPHAN , BERNDL GUNTHER , SIMON DIRK , SANNER AXEL
Abstract: Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric binder.
-
Patent Agency Ranking
公开(公告)号：PT1158962E
公开(公告)日：2003-04-30
申请号：PT00916925
申请日：2000-03-10
Applicant: BASF AG
Inventor： REINHOLD ULRICH , BERNDL GUNTHER , SIMON DIRK , LEHMANN STEPHAN
-
公开(公告)号：DK1158962T3
公开(公告)日：2003-01-06
申请号：DK00916925
申请日：2000-03-10
Applicant: BASF AG
Inventor： BERNDL GUNTHER , LEHMANN STEPHAN , REINHOLD ULRICH , SIMON DIRK
-
公开(公告)号：CA2367020A1
公开(公告)日：2000-09-21
申请号：CA2367020
申请日：2000-03-10
Applicant: BASF AG
Inventor： SIMON DIRK , REINHOLD ULRICH , LEHMANN STEPHAN , BERNDL GUNTHER
IPC: A01N25/08 , A01N25/10 , A61K8/73 , A61K8/86 , A61K9/20 , A61K9/22 , A61K31/192 , A61K31/565 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/40 , A61K47/48 , A61Q19/00
Abstract: The invention relates to a method for producing solid dosage forms containin g at least one physiologically compatible polymer binding agent, at least one active agent and at least one cyclodextrin as components. According to the method, the components are mixed and plasticised at a temperature below 220 ~C, without the addition of a solvent. The plastic mixture obtained is shape d into the dosage form. The invention also relates to the dosage forms obtaine d by said method.
-
公开(公告)号：DE19812688A1
公开(公告)日：1999-09-30
申请号：DE19812688
申请日：1998-03-23
Applicant: BASF AG
Inventor： KOTHRADE STEPHAN , BERNDL GUNTHER , SIMON DIRK , SANNER AXEL
Abstract: Solid dosage forms contain a water-swellable graft copolymer (I) as binder. An Independent claim is also included for the production of solid dosage forms by mixing (I) with active ingredient(s) and optionally additives, preferably in an extruder, and shaping the resulting plastic mixture.
-
公开(公告)号：DE50000866D1
公开(公告)日：2003-01-16
申请号：DE50000866
申请日：2000-03-10
Applicant: BASF AG
Inventor： BERNDL GUNTHER , REINHOLD ULRICH , SIMON DIRK , LEHMANN STEPHAN
-
-
-
-
-
-
-
-
-
Search Results
16
records
(took 0.033 seconds)
