公开(公告)号：DE3009034A1

公开(公告)日：1981-09-24

申请号：DE3009034

申请日：1980-03-08

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR ,  TESCHENDORF HANS JUERGEN DR ,  LENKE HANS-DIETER PROF DR

IPC: C07D295/14 ,  A61K31/275 ,  A61K31/395 ,  A61K31/50 ,  A61K31/55 ,  A61P25/20 ,  C07C67/00 ,  C07C253/00 ,  C07C255/37 ,  C07C255/42 ,  C07D243/08 ,  C07D295/08 ,  C07D295/155 ,  C07D295/04 ,  C07C121/48 ,  A61K31/00

Abstract: 10-Substituted 5-cyanomethylene-dibenzo[a,d]-cycloheptenes, their pure cis- and trans-isomers, their N-oxides and their pharmaceutically tolerated addition salts with acids, processes for their preparation, therapeutic agents containing these compounds and their use as drugs, especially as sedatives, hypnotics or tranquilizers.

公开(公告)号：CZ287862B6

公开(公告)日：2001-02-14

申请号：CZ31097

申请日：1995-07-21

Applicant: BASF AG

Inventor： STEINER GERD DR ,  MUNSCHAUER RAINER DR ,  HOEGER THOMAS DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS JUERGEN DR

IPC: C07D401/06 ,  A61K31/40 ,  A61K31/415 ,  A61K31/47 ,  A61K31/505 ,  A61P25/18 ,  A61P43/00 ,  C07D403/06 ,  C07D471/04 ,  C07D513/04 ,  A61K31/403

Abstract: In the present invention there are disclosed the compounds of the general formula I, in which Re1, Re2, A, X, Y and Z have specific meaning and process of their preparation. The invented novel compounds are suitable for treating diseases of nervous system.

公开(公告)号：DE3009045A1

公开(公告)日：1981-09-24

申请号：DE3009045

申请日：1980-03-08

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR ,  TESCHENDORF HANS JUERGEN DR

IPC: C07D243/08 ,  A61K31/00 ,  A61K31/395 ,  A61P25/02 ,  A61P25/08 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D295/088 ,  C07D295/14 ,  C07D295/155 ,  C07D295/04 ,  C07C121/48

Abstract: 10-Substituted 5-cyanomethylene-10,11-dihydro-dibenzo[a,d]-cycloheptenes, their pharmaceutically tolerated addition salts with acids, processes for their preparation, and their use as drugs, especially as sedatives, hypnotics or tranquilizers.

公开(公告)号：DE2918778A1

公开(公告)日：1980-11-20

申请号：DE2918778

申请日：1979-05-10

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  FRANKE ALBRECHT DIPL CHEM DR ,  LENKE HANS-DIETER PROF DR ,  TESCHENDORF HANS JUERGEN DR ,  WORSTMANN WOLFGANG DR ,  KREISKOTT HORST DR

IPC: A61K31/55 ,  A61P25/18 ,  C07D223/20 ,  C07D401/06 ,  C07D403/04 ,  C07D498/04 ,  C07D401/04 ,  A61K31/395

Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.