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公开(公告)号：GR75787B
公开(公告)日：1984-08-02
申请号：GR810165898
申请日：1981-08-31
Applicant: BASF AG
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公开(公告)号：DE3026331A1
公开(公告)日：1982-02-18
申请号：DE3026331
申请日：1980-07-11
Applicant: BASF AG
Inventor： FRANKE ALBRECHT DIPL CHEM DR , LENKE DIETER PROF DR , GRIES JOSEF DR MED , WEIFENBACH HARALD DR , KREISKOTT HORST DR , HOFMANN HANS PETER DR
IPC: C07D295/08 , A61K31/495 , A61P9/12 , A61P25/20 , C07C45/70 , C07D295/092 , C07D303/22 , C07D295/04
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3.发明专利
公开(公告)号：DE3374066D1
公开(公告)日：1987-11-19
申请号：DE3374066
申请日：1983-07-06
Applicant: BASF AG
Inventor： ALBRECHT HANS PETER DR , KREISKOTT HORST DR
IPC: C07D209/42 , A61K38/00 , A61P25/00 , A61P25/24 , A61P25/26 , A61P25/28 , C07D207/34 , C07K1/02 , C07K1/06 , C07K5/06 , C07K5/08 , C07K5/097 , A61K37/02
Abstract: Novel N-acyl derivatives of peptides related to L-pro-L-leu-gly-NH2, melanocyte stimulating hormone-release inhibiting factor (MIF), and therapeutic compositions which are useful for the treatment of depression.
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公开(公告)号：DE3161895D1
公开(公告)日：1984-02-16
申请号：DE3161895
申请日：1981-09-17
Applicant: BASF AG
Inventor： STEINER GERD DR , TESCHENDORF HANS-JUERGEN DR , KREISKOTT HORST DR , HOFMANN HANS PETER DR
IPC: A61K31/55 , A61P25/00 , A61P25/08 , A61P25/20 , C07D223/00 , C07D333/00 , C07D495/14
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公开(公告)号：DE3134775A1
公开(公告)日：1983-03-10
申请号：DE3134775
申请日：1981-09-02
Applicant: BASF AG
Inventor： STEINER GERD DIPL CHEM DR , HOFMANN HANS-PETER DR , KREISKOTT HORST DR , TESCHENDORF HANS-JUERGEN DR , LENKE HANS-DIETER PROF DR
IPC: C07D295/155 , C07D241/04 , A61K31/495
Abstract: The invention relates to 5-cyanomethylenedibenzo[a,d]cycloheptenes which are substituted in the 10 position, to processes for their preparation, to therapeutic agents containing these compounds, and to their use as sedatives, hypnotic agents, tranquillisers and neuroleptic agents.
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Patent Agency Ranking
公开(公告)号：DE3108426A1
公开(公告)日：1982-09-23
申请号：DE3108426
申请日：1981-03-06
Applicant: BASF AG
Inventor： STEINER GERD DIPL CHEM DR , HOFMANN HANS PETER DR , KREISKOTT HORST DR , TESCHENDORF HANS-JUERGEN DR ME
IPC: C07D223/20 , C07D403/04 , A61K31/55
Abstract: The invention relates to 11-chloromethylenemorphanthridines substituted in the 6-position, which are also called 11-chloromethylenedibenzo[b,e]azepines, processes for their preparation and therapeutic compositions containing them, which can be used as sedatives, hypnotics, tranquillisers or neuroleptics.
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公开(公告)号：DE3101502A1
公开(公告)日：1982-08-26
申请号：DE3101502
申请日：1981-01-19
Applicant: BASF AG
Inventor： THIEME PETER C DR , STEINER GERD DR , ROHR WOLFGANG DR , LENKE DIETER PROF DR , GRIES JOSEF DR MED , WEIFENBACH HARALD DR , TESCHENDORF HANS-JUERGEN DR ME , HOFMANN HANS PETER DR , KREISKOTT HORST DR
IPC: C07D249/08 , A61K31/41 , A61K31/415 , A61K31/495 , A61K31/496 , A61P9/02 , A61P11/00 , A61P25/20 , C07D231/12 , C07D233/60 , C07D233/61 , C07D271/10 , C07D295/06 , C07D295/067 , C07D295/096 , C07D521/00 , C07D403/12 , C07D413/12
Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.
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公开(公告)号：DE3009034A1
公开(公告)日：1981-09-24
申请号：DE3009034
申请日：1980-03-08
Applicant: BASF AG
Inventor： STEINER GERD DIPL CHEM DR , HOFMANN HANS PETER DR , KREISKOTT HORST DR , TESCHENDORF HANS JUERGEN DR , LENKE HANS-DIETER PROF DR
IPC: C07D295/14 , A61K31/275 , A61K31/395 , A61K31/50 , A61K31/55 , A61P25/20 , C07C67/00 , C07C253/00 , C07C255/37 , C07C255/42 , C07D243/08 , C07D295/08 , C07D295/155 , C07D295/04 , C07C121/48 , A61K31/00
Abstract: 10-Substituted 5-cyanomethylene-dibenzo[a,d]-cycloheptenes, their pure cis- and trans-isomers, their N-oxides and their pharmaceutically tolerated addition salts with acids, processes for their preparation, therapeutic agents containing these compounds and their use as drugs, especially as sedatives, hypnotics or tranquilizers.
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公开(公告)号：DE3171074D1
公开(公告)日：1985-07-25
申请号：DE3171074
申请日：1981-12-23
Applicant: BASF AG
Inventor： THIEME PETER C DR , STEINER GERD DR , ROHR WOLFGANG DR , LENKE DIETER DR , GRIES JOSEF DR , WEIFENBACH HARALD DR , TESCHENDORF HANS-JUERGEN DR , HOFMANN HANS PETER DR , KREISKOTT HORST DR
IPC: C07D249/08 , A61K31/41 , A61K31/415 , A61K31/495 , A61K31/496 , A61P9/02 , A61P11/00 , A61P25/20 , C07D231/12 , C07D233/60 , C07D233/61 , C07D271/10 , C07D295/06 , C07D295/067 , C07D295/096 , C07D521/00
Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.
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公开(公告)号：DE3064096D1
公开(公告)日：1983-08-18
申请号：DE3064096
申请日：1980-05-05
Applicant: BASF AG
Inventor： STEINER GERD DR , FRANKE ALBRECHT DR , LENKE DIETER DR , TESCHENDORF HANS-JUERGEN DR , WORSTMANN WOLFGANG DR , KREISKOTT HORST DR
IPC: A61K31/55 , A61P25/18 , C07D223/20 , C07D401/06 , C07D403/04
Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.
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