公开(公告)号：DE3037971A1

公开(公告)日：1982-05-13

申请号：DE3037971

申请日：1980-10-08

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  TESCHENDORF HANS-JUERGEN DR ME ,  KREISKOTT HORST DR ,  HOFMANN HANS PETER DR

IPC: A61K31/55 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  C07D223/00 ,  C07D333/00 ,  C07D495/14 ,  C07D495/12 ,  A61K31/35

公开(公告)号：DE2918832A1

公开(公告)日：1980-11-20

申请号：DE2918832

申请日：1979-05-10

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  FRANKE ALBRECHT DIPL CHEM DR

IPC: C07D223/20 ,  C07D403/04 ,  C07D233/20 ,  C07D401/04

公开(公告)号：DE3101456A1

公开(公告)日：1982-09-02

申请号：DE3101456

申请日：1981-01-19

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DIPL CHEM DR ,  STEINER GERD DIPL CHEM DR ,  THIEME PETER C DIPL CHEM DR ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR MED ,  TESCHENDORF HANS-JUERGEN DR ME

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00 ,  C07D403/12 ,  C07D403/10 ,  C07D413/12 ,  C07D413/10

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：DE3309596A1

公开(公告)日：1984-04-05

申请号：DE3309596

申请日：1983-03-17

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  MUELLER CLAUS-DIETER DR ,  LENKE DIETER DR

IPC: A61K31/435 ,  C07D471/04 ,  A61K31/475

公开(公告)号：DE3134775A1

公开(公告)日：1983-03-10

申请号：DE3134775

申请日：1981-09-02

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  HOFMANN HANS-PETER DR ,  KREISKOTT HORST DR ,  TESCHENDORF HANS-JUERGEN DR ,  LENKE HANS-DIETER PROF DR

IPC: C07D295/155 ,  C07D241/04 ,  A61K31/495

Abstract: The invention relates to 5-cyanomethylenedibenzo[a,d]cycloheptenes which are substituted in the 10 position, to processes for their preparation, to therapeutic agents containing these compounds, and to their use as sedatives, hypnotic agents, tranquillisers and neuroleptic agents.

公开(公告)号：DE3108426A1

公开(公告)日：1982-09-23

申请号：DE3108426

申请日：1981-03-06

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR ,  TESCHENDORF HANS-JUERGEN DR ME

IPC: C07D223/20 ,  C07D403/04 ,  A61K31/55

Abstract: The invention relates to 11-chloromethylenemorphanthridines substituted in the 6-position, which are also called 11-chloromethylenedibenzo[b,e]azepines, processes for their preparation and therapeutic compositions containing them, which can be used as sedatives, hypnotics, tranquillisers or neuroleptics.

公开(公告)号：DE3009034A1

公开(公告)日：1981-09-24

申请号：DE3009034

申请日：1980-03-08

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR ,  TESCHENDORF HANS JUERGEN DR ,  LENKE HANS-DIETER PROF DR

IPC: C07D295/14 ,  A61K31/275 ,  A61K31/395 ,  A61K31/50 ,  A61K31/55 ,  A61P25/20 ,  C07C67/00 ,  C07C253/00 ,  C07C255/37 ,  C07C255/42 ,  C07D243/08 ,  C07D295/08 ,  C07D295/155 ,  C07D295/04 ,  C07C121/48 ,  A61K31/00

Abstract: 10-Substituted 5-cyanomethylene-dibenzo[a,d]-cycloheptenes, their pure cis- and trans-isomers, their N-oxides and their pharmaceutically tolerated addition salts with acids, processes for their preparation, therapeutic agents containing these compounds and their use as drugs, especially as sedatives, hypnotics or tranquilizers.

公开(公告)号：DE3113094A1

公开(公告)日：1982-10-21

申请号：DE3113094

申请日：1981-04-01

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER PROF DR

IPC: A61K31/00 ,  A61K31/55 ,  A61P1/04 ,  C07D223/20 ,  C07D401/06 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D413/12 ,  C07F9/59 ,  C07D413/06

公开(公告)号：DE3108427A1

公开(公告)日：1982-09-23

申请号：DE3108427

申请日：1981-03-06

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR ,  TESCHENDORF HANS-JUERGEN DR ME

IPC: C07D263/20 ,  C07D495/14 ,  C07D413/14 ,  A61K31/42 ,  A61K31/495 ,  A61K31/55 ,  C07D409/14 ,  C07D413/06 ,  C07D495/06

Abstract: The invention relates to tricyclic 3-[2-(1-piperazinyl)ethyl]-2-oxazolidinone derivatives, process for their preparation and therapeutic compositions which contain them and can be used as sedatives, hypnotics, tranquillisers or neuroleptics.

公开(公告)号：DE3009045A1

公开(公告)日：1981-09-24

申请号：DE3009045

申请日：1980-03-08

Applicant: BASF AG

Inventor： STEINER GERD DIPL CHEM DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR ,  TESCHENDORF HANS JUERGEN DR

IPC: C07D243/08 ,  A61K31/00 ,  A61K31/395 ,  A61P25/02 ,  A61P25/08 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D295/088 ,  C07D295/14 ,  C07D295/155 ,  C07D295/04 ,  C07C121/48

Abstract: 10-Substituted 5-cyanomethylene-10,11-dihydro-dibenzo[a,d]-cycloheptenes, their pharmaceutically tolerated addition salts with acids, processes for their preparation, and their use as drugs, especially as sedatives, hypnotics or tranquilizers.