-
公开(公告)号：CA2818390A1
公开(公告)日：2012-05-31
申请号：CA2818390
申请日：2011-11-18
Applicant: BIO RAD LABORATORIES
Inventor： ARCHER ROBERT M , HSIUNG FRANK , PATT PAUL
Abstract: Adherent cells bearing characteristics that are detectable only in the adherent state can be sorted on the basis of these characteristics independently of their adherent state, by applying a transformable label to the entire population of cells, both those bearing the characteristics of interest and those not, in their adherent state and identifying the locations of the cells of interest on the adherent surface. The cells of interest, or all cells other than those of interest, are then selectively treated to transform the labels and achieve differentiation between the cells of interest and the remaining cells. All cells are then released from the adherent state and sorted in the same manner as non-adherent cells but on the basis of whether the labels are transformed or not transformed.
-
Patent Agency Ranking
公开(公告)号：CA2818390C
公开(公告)日：2017-08-22
申请号：CA2818390
申请日：2011-11-18
Applicant: BIO-RAD LABORATORIES INC
Inventor： ARCHER ROBERT M , HSIUNG FRANK , PATT PAUL
Abstract: Adherent cells bearing characteristics that are detectable only in the adherent state can be sorted on the basis of these characteristics independently of their adherent state, by applying a transformable label to the entire population of cells, both those bearing the characteristics of interest and those not, in their adherent state and identifying the locations of the cells of interest on the adherent surface. The cells of interest, or all cells other than those of interest, are then selectively treated to transform the labels and achieve differentiation between the cells of interest and the remaining cells. All cells are then released from the adherent state and sorted in the same manner as non-adherent cells but on the basis of whether the labels are transformed or not transformed.
-
公开(公告)号：WO2012071275A3
公开(公告)日：2012-07-26
申请号：PCT/US2011061425
申请日：2011-11-18
Applicant: BIO RAD LABORATORIES , ARCHER ROBERT M , HSIUNG FRANK , PATT PAUL
Inventor： ARCHER ROBERT M , HSIUNG FRANK , PATT PAUL
CPC classification number: G01N33/5094 , G01N15/0606 , G01N15/1463 , G01N2015/0288 , G01N2015/149
Abstract: Adherent cells bearing characteristics that are detectable only in the adherent state can be sorted on the basis of these characteristics independently of their adherent state, by applying a transformable label to the entire population of cells, both those bearing the characteristics of interest and those not, in their adherent state and identifying the locations of the cells of interest on the adherent surface. The cells of interest, or all cells other than those of interest, are then selectively treated to transform the labels and achieve differentiation between the cells of interest and the remaining cells. All cells are then released from the adherent state and sorted in the same manner as non-adherent cells but on the basis of whether the labels are transformed or not transformed.
Abstract translation: 通过对整个细胞群施加可转化的标记（无论是具有感兴趣特征还是未感兴趣特征的细胞），可以根据这些特征独立于它们的粘附状态对具有仅可检测到粘附状态的特征的粘附细胞进行分类， 处于其粘附状态并识别粘附表面上感兴趣细胞的位置。 然后选择性处理感兴趣的细胞或感兴趣的细胞以外的所有细胞以转化标记并实现感兴趣的细胞和剩余细胞之间的区分。 然后从贴壁状态释放所有细胞，并按照与非贴壁细胞相同的方式分类，但基于标记是否被转化或未转化。
-
4.发明公开SORTING OF ADHERENT CELLS BY SELECTIVE TRANSFORMATION OF LABELS 有权SORTIEREN BENACHBARTER ZELLEN DURCH SELEKTIVE UMWANDLUNG VON ETIKETTEN
公开(公告)号：EP2643453A4
公开(公告)日：2014-06-11
申请号：EP11843656
申请日：2011-11-18
Applicant: BIO RAD LABORATORIES
Inventor： ARCHER ROBERT M , HSIUNG FRANK , PATT PAUL
CPC classification number: G01N33/5094 , G01N15/0606 , G01N15/1463 , G01N2015/0288 , G01N2015/149
-
公开(公告)号：EP2992377A4
公开(公告)日：2017-03-08
申请号：EP14791630
申请日：2014-05-01
Applicant: BIO-RAD LABORATORIES INC
Inventor： HSIUNG FRANK , KROEGER KELLY , ARCHER ROBERT , KORTISOVA VERONIKA , RUBIO TERESA , SHEN ZUO CHENG , CHU DANIEL Y , DOE NICHOLAS , QUIROZ EMMANUEL
CPC classification number: G02B21/368 , G02B21/241 , G02B21/365
Abstract: The present invention relates in general to microscopy systems. In particular, the present invention relates to microscopes rendering digital images of samples, with the capability to digitally control the focus of the microscope system, and the software used to control the operation of the digital microscope system. Further, the present invention relates to a microscope structure that allows for compact and multi-functional use of a microscope, providing for light shielding and control with samples that require specific light wavelength characteristics, such as fluorescence, for detection and imaging.
-
6.发明公开AFFINITY-BASED PARTITION ASSAY FOR DETECTION OF TARGET MOLECULES 审中-公开测试麻省理工学院研究生毕业生毕业生ZUM NACHWEIS VONZIELMOLEKÜLEN
公开(公告)号：EP2954102A4
公开(公告)日：2017-01-04
申请号：EP14748862
申请日：2014-02-05
Applicant: BIO-RAD LABORATORIES INC
Inventor： MCCOY ADAM M , TZONEV SVILEN , HSIUNG FRANK
IPC: C40B20/04 , C12Q1/00 , G01N33/542 , G01N33/58
CPC classification number: C12Q1/00 , G01N33/542 , G01N33/581
Abstract: The present invention provides methods of detecting a target molecule in a sample comprising incubating the sample with two or more detectably labeled probes, partitioning the sample into multiple partitions, and detecting the presence of the two or more probes in the same partition.
Abstract translation: 本发明提供检测样品中靶分子的方法，包括用两个或多个可检测标记的探针孵育样品，将样品分成多个分区，以及检测两个或更多个探针在同一分区中的存在。
-
-
-
-
-
Search Results
6
records
(took 0.021 seconds)
