公开(公告)号：US3902115A

公开(公告)日：1975-08-26

申请号：US40098673

申请日：1973-09-26

Applicant: COULTER ELECTRONICS

Inventor： HOGG WALTER R ,  COULTER WALLACE H ,  GINSBERG GUENTER ,  PRONI OSCAR ,  GODIN THOMAS J

IPC: G01N1/38 ,  G01N15/12 ,  G01N27/00

CPC classification number: G01N15/12 ,  G01N1/38 ,  G01N15/1218

Abstract: A two chamber aperture tube for obtaining signals from particles suspended in a fluid which passes through a scanning aperture. The suspension enters an aperture in an inlet chamber and passes thereafter to an outlet chamber in fluid connection with the inlet chamber. The inlet chamber of the tube is connected to a source of clean electrolyte; the outlet chamber is connected to a waste collecting container. A vacuum is applied to the collecting container to cause clean electrolyte to be drawn through the inlet chamber and wash behind the aperture simultaneously with passage of the suspension through the aperture. A restriction in the path of flow of the clean electrolyte causes the flow velocity thereof to increase behind the aperture and ensure that proper signals from all particles in the suspension are obtained.

公开(公告)号：US3515494A

公开(公告)日：1970-06-02

申请号：US3515494D

申请日：1968-04-09

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR

IPC: F04D9/00 ,  F04D9/02 ,  F04D29/22 ,  F04D29/42 ,  F04D13/02 ,  F04D29/08

CPC classification number: F04D9/02 ,  F04D9/002 ,  F04D29/2277 ,  F04D29/426

公开(公告)号：DE3584646D1

公开(公告)日：1991-12-19

申请号：DE3584646

申请日：1985-01-24

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR ,  JAMES BOBBY DENCIL

IPC: G01N15/12 ,  G01N27/00

Abstract: A particle analyzing apparatus and method of moving and counting particles in suspension through such an apparatus. The particle analyzing apparatus comprises a particle counting device wherein particles in suspension are caused to be moved through an aperture whose effective impedance is changed with the passage of each particle therethrough and a fluid connection means for drawing a quantity of the suspension through the aperture, including a source of vacuum. The source of vacuum comprises a bellows having an end, and a constant force means connected to the end of the bellows means.

公开(公告)号：CA1247678A

公开(公告)日：1988-12-28

申请号：CA473291

申请日：1985-01-31

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR ,  JAMES BOBBY D

IPC: G01N15/12 ,  G01N27/00

Abstract: A particle analyzing apparatus (10) and method of moving and counting particles in suspension through such an apparatus. The particle analyzing apparatus comprises a particle counting device (16) wherein particles in suspension are caused to be moved through an aperture (24) whose effective impedance is changed with the passage of each particle therethrough and a fluid connection means (18) for drawing a quantity of the suspension through the aperture, including a source of vacuum (30). The source of vacuum comprises a bellows (60) having an end (64), and a constant force means (66) connected to the end of the bellows means.

公开(公告)号：CA1029985A

公开(公告)日：1978-04-25

申请号：CA217675

申请日：1975-01-09

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR ,  MELNICK LORAN V ,  HENDERSON WILLIAM T

IPC: B01F20060101 ,  B01F

公开(公告)号：DE2410720A1

公开(公告)日：1974-09-12

申请号：DE2410720

申请日：1974-03-06

Applicant: COULTER ELECTRONICS

Inventor： BULL BRIAN STANLEY ,  PRONI OSCAR ,  MELNICK LORAN V

IPC: G01N33/48 ,  B04B5/02 ,  B04B5/04 ,  B04B13/00

Abstract: A centrifuge for production of platelet rich plasma by accelerated sedimentation of whole blood. The centrifuge is adapted to apply greater than gravity force laterally, that is, approximately perpendicular, to the long axis of a thin cylindrical container partially filled with whole blood. The centrifuge includes cam actuated timer means cyclically operating a centrifuge head in which the cylindrical containers are held. Drive means are provided to rotate the head and said timer means includes means controlling the coupling of said drive means with said head whereby said head is driven for a predetermined duration, the drive means deenergized and the head is uncoupled therefrom to a free rotational state during which a gradual slowdown is effected to permit the vertically oriented column of blood to return from the side of the container to the bottom smoothly and with mixing within the plasma and cell layers but not between the two layers. Also provided are alarm means for indicating the expiration of a predetermined time during which the head is at rest so as to enable the operator to be certain sufficient time has elapsed to accomplish the required degree of sedimentation.

公开(公告)号：CA961019A

公开(公告)日：1975-01-14

申请号：CA152378

申请日：1972-09-22

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR

IPC: G01N33/49 ,  B04B5/02 ,  B04B5/04 ,  B04B11/00 ,  G01N15/04 ,  G01N15/05 ,  G01N33/483

公开(公告)号：AU575378B2

公开(公告)日：1988-07-28

申请号：AU3935385

申请日：1985-01-24

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR ,  JAMES BOBBY DENCIL

IPC: G01N15/12 ,  G01N1/14

Abstract: A particle analyzing apparatus and method of moving and counting particles in suspension through such an apparatus. The particle analyzing apparatus comprises a particle counting device wherein particles in suspension are caused to be moved through an aperture whose effective impedance is changed with the passage of each particle therethrough and a fluid connection means for drawing a quantity of the suspension through the aperture, including a source of vacuum. The source of vacuum comprises a bellows having an end, and a constant force means connected to the end of the bellows means.

公开(公告)号：BR8505007A

公开(公告)日：1986-01-21

申请号：BR8505007

申请日：1985-01-24

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR ,  JAMES BOBBY DENCIL

IPC: G01N15/12 ,  G01N27/00

Abstract: A particle analyzing apparatus and method of moving and counting particles in suspension through such an apparatus. The particle analyzing apparatus comprises a particle counting device wherein particles in suspension are caused to be moved through an aperture whose effective impedance is changed with the passage of each particle therethrough and a fluid connection means for drawing a quantity of the suspension through the aperture, including a source of vacuum. The source of vacuum comprises a bellows having an end, and a constant force means connected to the end of the bellows means.

公开(公告)号：AU3935385A

公开(公告)日：1985-08-27

申请号：AU3935385

申请日：1985-01-24

Applicant: COULTER ELECTRONICS

Inventor： PRONI OSCAR ,  JAMES BOBBY DENCIL

IPC: G01N15/12 ,  G01N27/00

Abstract: A particle analyzing apparatus and method of moving and counting particles in suspension through such an apparatus. The particle analyzing apparatus comprises a particle counting device wherein particles in suspension are caused to be moved through an aperture whose effective impedance is changed with the passage of each particle therethrough and a fluid connection means for drawing a quantity of the suspension through the aperture, including a source of vacuum. The source of vacuum comprises a bellows having an end, and a constant force means connected to the end of the bellows means.