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1.发明授权Self-cleaning aperture tube for coulter study apparatus and electrolyte supply system therefor 失效自清洁孔管用于水泥研究设备及其电解质供应系统
公开(公告)号：US3902115A
公开(公告)日：1975-08-26
申请号：US40098673
申请日：1973-09-26
Applicant: COULTER ELECTRONICS
Inventor： HOGG WALTER R , COULTER WALLACE H , GINSBERG GUENTER , PRONI OSCAR , GODIN THOMAS J
CPC classification number: G01N15/12 , G01N1/38 , G01N15/1218
Abstract: A two chamber aperture tube for obtaining signals from particles suspended in a fluid which passes through a scanning aperture. The suspension enters an aperture in an inlet chamber and passes thereafter to an outlet chamber in fluid connection with the inlet chamber. The inlet chamber of the tube is connected to a source of clean electrolyte; the outlet chamber is connected to a waste collecting container. A vacuum is applied to the collecting container to cause clean electrolyte to be drawn through the inlet chamber and wash behind the aperture simultaneously with passage of the suspension through the aperture. A restriction in the path of flow of the clean electrolyte causes the flow velocity thereof to increase behind the aperture and ensure that proper signals from all particles in the suspension are obtained.
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公开(公告)号：US3894438A
公开(公告)日：1975-07-15
申请号：US38346473
申请日：1973-07-27
Applicant: COULTER ELECTRONICS
Inventor： GINSBERG GUENTER
CPC classification number: G01N35/1009 , G01F23/161 , G01N2035/1025
Abstract: A pneumatically responsive level sensor controls the positioning and sampling action of a sampling probe. The sensor and probe are moved synchronously, with the sampling probe extending into the sample at the time that the level sensor reaches the surface of the sample. The level sensor actuates a fluidic turbulence amplifier, which triggers a pneumatic-electric switch, for providing various sampling, positioning, and pneumatic activities.
Abstract translation: 气动响应液位传感器控制采样探头的定位和采样动作。 传感器和探头同步移动，当液位传感器到达样品表面时，采样探头延伸到样品中。 液位传感器启动流体湍流放大器，其触发气动电开关，用于提供各种取样，定位和气动活动。
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公开(公告)号：US3882899A
公开(公告)日：1975-05-13
申请号：US38274173
申请日：1973-07-26
Applicant: COULTER ELECTRONICS
Inventor： GINSBERG GUENTER , GODIN THOMAS JOHN , SIMPSON RONALD OLIN
CPC classification number: F04B9/12 , F04B7/02 , F04B7/0275 , F04B9/1222 , F16K7/06 , F16K11/027 , G01F11/021 , G01F15/005 , Y10T137/86919
Abstract: A pneumatically controlled liquid transfer system for delivering a liquid from a source to a delivery location, said liquid source being provided with a pneumatic cylinder for driving the liquid from said source, a pneumatically operated pinch valve of the make-before-break type and flexible conduit paths leading through the valve to the delivery location. The make-before-break pinch valve comprises a valve shell having two pistons movable laterally therein. The shell has a window. One piston has a yoke, each arm thereof having a passageway, one aligned with the other. A stop extends between the arms of the yoke. One of the flexible conduits is arranged through the window between the first piston and the yoke and the other flexible conduit is arranged also through the window but within the aligned passageways and between the piston and post. The second piston is spring biased to bear against the second conduit to place same in a normally closed condition. The first conduit is normally open. The first piston is acted upon by an external force such as air pressure to move same to a first condition wherein the piston pinches the first flexible conduit against the yoke, closing said conduit without overcoming the bias of the second piston to open the second conduit. Continued force exercised upon said first piston causes the same to move laterally within the housing to a second condition overcoming the spring bias of the second piston, to open the second conduit while the first conduit is retained in closed position. The second piston by virtue of its spring bias, will force the yoke back into its first position once the pressure on the first piston is relaxed. A manual override is provided operative upon the second piston to lock the same in open condition so that both conduits are open. This last mentioned position is utilized during down time of the apparatus concerned.
Abstract translation: 一种用于将液体从源输送到输送位置的气动控制液体转移系统，所述液体源设置有用于驱动来自所述源的液体的气缸，气动操作的断开前类型的弹性阀和柔性 通过阀门到达输送位置的导管路径。 制动前打击夹紧阀包括具有两个在其中横向移动的活塞的阀壳。 外壳有一个窗口。 一个活塞具有轭，每个臂具有通道，一个与另一个对准。 止动器在轭的臂之间延伸。 柔性管道中的一个布置成穿过第一活塞和轭之间的窗口，另一个柔性导管也布置在窗口内，但是在对齐的通道内以及活塞和柱之间。 第二活塞被弹簧偏压以抵靠第二导管以将其放置在常闭状态。 第一个导管是常开的。 第一活塞由诸如空气压力的外力作用，以将其移动到第一状态，其中活塞将第一柔性导管夹在轭上，闭合所述导管而不克服第二活塞的偏压以打开第二导管。 在所述第一活塞上施加的持续力使其在壳体内横向移动到克服第二活塞的弹簧偏压的第二状态，以在第一导管保持在关闭位置时打开第二导管。 第二活塞由于其弹簧偏压，一旦放松第一活塞上的压力就会迫使轭回到其第一位置。 在第二活塞上操作手动操作以将其锁定在开启状态，使得两个管道都是打开的。 最后提到的位置在有关设备的停机时间被利用。
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公开(公告)号：DE3172933D1
公开(公告)日：1986-01-02
申请号：DE3172933
申请日：1981-01-22
Applicant: COULTER ELECTRONICS
Inventor： GINSBERG GUENTER , HODGINS BRUCE
Abstract: A sample and stat feeding system (10) for sequentially supplying a renewable supply of cuvettes (20) with aliquots of sample liquids in a continuous processing mode. The sample liquids are contained in an annular sample tray (50) having a plurality of sample vessels molded into the tray. The sample containers form two or more annular rows (56, 58) on the outer edge of the tray in which routine samples are maintained in an ordered sequence. Emergency samples (stats) and controls (standards) are maintained in separate auxiliary locations or arrays of locations (54) which may be molded or separate cups placed in tray cavities. A sample pick up mechanism has a pick up probe (36) which is rotated to define an arc across at least substantial portion of the tray (50) and at least one stat location. The tray (50) is rotated to align the sample, stat and control cavities with the arc of the probe. Sample aliquots are picked up and dispensed into the cuvettes (20) in a programed operation sequence, with each sample fluid being related to a particular patient and programed for one or more analytical tests such as measuring the chemical reaction resulting from the addition of one or more reagents from a reagent supply. The program sequencing includes inserting a control aliquot in some of the cuvettes (20) at a predetermined frequency to monitor the accuracy of the machine. When a stat test occurs, the stat is inserted in the tray (50) and the programed sequence is interrupted to load the stat into the reaction vessel. The order of sample locations is not disturbed since the stats and controls are maintained in separate locations. The sample tray (50) preferably wilt be molded of inexpensive material so it may be thrown away after all sample aliquots have been loaded into respective cuvettes for testina.
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公开(公告)号：CA1138221A
公开(公告)日：1982-12-28
申请号：CA391039
申请日：1981-11-26
Applicant: COULTER ELECTRONICS
Inventor： GINSBERG GUENTER , HORNE THOMAS , KREISELMAN ROBERT L
IPC: G01N35/04
Abstract: Apparatus for measuring progressively the absorbance changes of a large number of aliquots from a plurality of different samples. The sample introduction, testing instructions, aliquot preparation, reagent dispensing, absorbance measuring and data recording all can be accomplished in a continuous mode of processing. Stat and batch operation also can be accomplished. The aliquots are in an array of cuvettes which is advanced slowly along a circular path. Photometer means, preferably having several photometric detectors, are mounted in fixed orientation on a common support that advances rapidly along a similar circular path, such that radiation passing through each of the cuvettes is monitored many times by a specific photometric detector by the time that cuvette completes one circuit of its path. The photometric detectors can operate at several different wavelengths. Many different chemical reactions can be monitored at the same time, The radiant energy passing through each cuvette is received by the continuously moving photometer means, is converted electrically into a digitized value proportional to absorbance and is transmitted digitally from the moving assemblage of photometric detectors, cuvettes and electrical components to a stationary receiver. In one embodiment, the digital transmission is in the form of a pulsed train of light signals. In another embodiment, one or more slip rings transmit electric signals from the moving assemblage to the stationary portion. Suitable drive elements, sample and reagent storage and transfer mechanisms as well as cuvette laundry means may be provided as part of the complete apparatus.
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Patent Agency Ranking
公开(公告)号：CA1116430A
公开(公告)日：1982-01-19
申请号：CA305783
申请日：1978-06-19
Applicant: COULTER ELECTRONICS
Inventor： GINSBERG GUENTER , HORNE THOMAS , KREISELMAN ROBERT L
Abstract: Apparatus for measuring progressively the absorbance changes of a large number of aliquots from a plurality of different samples. The sample introduction, testing instructions, aliquot preparation, reagent dispensing, absorbance measuring and data recording all can be accomplished in a continuous mode of processing. Stat and batch operation also can be accomplished. The aliquots are in an array of cuvettes which is advanced slowly along a circular path. Photometer means, preferably having several photometric detectors, are mounted in fixed orientation on a common support that advances rapidly along a similar circular path, such that radiation passing through each of the cuvettes is monitored many times by a specific photometric detector by the time that cuvette completes one circuit of its path. The photometric detectors can operate at several different wavelengths. Many different chemical reactions can be monitored at the same time. The radiant energy passing through each cuvette is received by the continuously moving photometer means, is converted electrically into a digitized value proportional to absorbance and is transmitted digitally from the moving assemblage of photometric detectors, cuvettes and electrical components to a stationary receiver. In one embodiment, the digital transmission is in the form of a pulsed train of light signals. In another embodiment, one or more slip rings transmit electric signals from the moving assemblage to the stationary portion. Suitable drive elements, sample and reagent storage and transfer mechanisms as well as cuvette laundry means may be provided as part of the complete apparatus.
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公开(公告)号：CH623931A5
公开(公告)日：1981-06-30
申请号：CH158178
申请日：1978-02-14
Applicant: COULTER ELECTRONICS
Inventor： SIMPSON RONALD O , STARLING J DAVID , JAMES BOBBY D , GODIN THOMAS JOHN , GINSBERG GUENTER , DRBAL VLADIMIR J , SZULGA ANATOLE
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公开(公告)号：DE2546234A1
公开(公告)日：1976-05-13
申请号：DE2546234
申请日：1975-10-15
Applicant: COULTER ELECTRONICS
Inventor： FIGUEROA DAVID RICHARD , GINSBERG GUENTER
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公开(公告)号：DE2448588A1
公开(公告)日：1975-09-18
申请号：DE2448588
申请日：1974-10-11
Applicant: COULTER ELECTRONICS
Inventor： GINSBERG GUENTER
Abstract: A backwash system including a dispensing cylinder and valve arrangement for directing diluent as a backwash from a source to a sampling valve utilized to make dilutions thence to a sampler in the form of an aspirator tube. The sampling is performed by means of the aspirator tube introduced into a fluid for sampling and a vessel is provided for catching the backwash fluid and aspirating same to waste. The vessel and the tube are positioned relatively to enable the backwash to be caught in the vessel only when diluent is dispensed as backwash. The aspirator tube and collector vessel are returned to their normal relative condition either by movement of the tube relative to the collector vessel or vice versa. Suitable controls are provided to assure that backwash occurs only when the tube and vessel are conditioned to receive same.
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公开(公告)号：DE2445411A1
公开(公告)日：1975-05-07
申请号：DE2445411
申请日：1974-09-23
Applicant: COULTER ELECTRONICS
Inventor： HOGG WALTER ROBERT , COULTER WALLACE HENRY , GINSBERG GUENTER , PRONI OSCAR , GODIN THOMAS J
Abstract: 1479901 Electro-physical measurement; particle analysis COULTER ELECTRONICS Ltd 23 Sept 1974 [26 Sept 1973] 41368/74 Heading G1N(C) In a Coulter type particle analyzer, a "twochamber" tube is provided whereby clean electrolyte can be flowed past the aperture to waste, in a manner similar to that disclosed in Specification 1341336 and a constriction in the flow-path is arranged to increase the velocity behind the aperture. OVERALL SYSTEM FIG. 1. A double tube 13 is sealed into a coupling block 19 attached by screws 59 to the head-block 58, for easy interchange. The electrolyte system is electrically isolated from waste 42 and supply reservoir 52 by drip feed tanks 24, 29. The sample and electrolyte are moved through the apparatus by vacuum applied to the waste drip tank 24. The clean electrolyte flow is regulated by a constriction 27. Several variations of double tube construction are disclosed with reference to Figs. 2 ... 13 which are substantially self explanatory. Figs. 2, 5, 6, 7 only are shown as typical.
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