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    MULTIWELL PLATE WITH VARIABLE COMPRESSION SEAL
    1.
    发明申请
    MULTIWELL PLATE WITH VARIABLE COMPRESSION SEAL 审中-公开

    公开(公告)号：WO2018209020A1

    公开(公告)日：2018-11-15

    申请号：PCT/US2018/031958

    申请日：2018-05-10

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： CLARK, Phillip ,  GREENIZEN, Kurt E. ,  DOYLE, John

    IPC: B01D29/00

    Abstract: Filtration apparatus for the assay of biological and biochemical reactants, for example, is provided and includes a substrate such as a plate having one or more wells open at each end, and a porous membrane positioned in each well forming a discrete filtering area. The filtration apparatus includes a seal that is in a compressible relationship with the face of the porous membrane, the surface of the compression element, and the well wall. Each well includes a compression element, such as an internal well insert or sleeve, which compresses the seal so that the seal contacts the membrane face, the surface of the compression element, and the well wall in a liquid-tight manner. The compression element may be configured so that it is fixed in the well such as by an interference fit with the well wall or by bonding to a surface of the substrate.

    GEL CAST CASSETTE AND HAND CAST SYSTEM
    2.
    发明申请
    GEL CAST CASSETTE AND HAND CAST SYSTEM 审中-公开

    公开(公告)号：WO2020146565A1

    公开(公告)日：2020-07-16

    申请号：PCT/US2020/012829

    申请日：2020-01-09

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： GREENIZEN, Kurt ,  SCOTT, Christopher ,  SYDLOWSKI, Paul ,  WU, Kevin ,  AMARA, Ryan ,  MANNING, Ryan ,  GUTIERREZ, Sara ,  DOYLE, John

    IPC: G01N27/447

    Abstract: The embodiments disclosed herein are directed to a device and assembly useful for hand casting an electrophoretic separation medium. The device includes a cassette frame 10 comprising first and second arms or members 12,22 pivotally connected to one another. One or more hinges 35A,35B may be provided to allow the first member to swing or pivot relative to the second member 12,22 (or vice versa) between a cassette frame open position and a cassette frame closed position. The first and second members 12,22 each include a substrate 20,30 to maintain a gel interface, preferably a glass plate substrate. The assembly includes a base and clamping arms that cooperate to hold one or more cassette frames in compressed relation.

    FILTRATION CLAMP WITH OPTIONAL ALIGNMENT COLLAR AND FILTRATION SYSTEM
    3.
    发明申请
    FILTRATION CLAMP WITH OPTIONAL ALIGNMENT COLLAR AND FILTRATION SYSTEM 审中-公开
    过滤夹具有可选择的校准曲线和过滤系统

    公开(公告)号：WO2017192269A1

    公开(公告)日：2017-11-09

    申请号：PCT/US2017/028485

    申请日：2017-04-20

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： GREENIZEN, Kurt E. ,  SCOTT, Christopher A. ,  SYDLOWSKI, Paul ,  DOYLE, John ,  AMARA, Ryan A.

    IPC: B25B7/14 ,  B25B7/02 ,  B25B7/12 ,  B25B1/04 ,  B25B3/00 ,  B25B5/04 ,  B25B5/08 ,  B25B5/12

    Abstract: A clamp including a first jaw member having a camming surface, a second jaw member pivotable with respect to the first jaw member, a first biasing member biasing the first and second jaw members to a first position; and a locking mechanism that includes a cam or roller for cooperating with the camming surface of the jaw member, and a second biasing member biasing the cam or roller against the camming surface to lock the first and second jaw members in a second position. An optional alignment collar can be used to align components of the filtration apparatus prior to clamping. Filtration apparatus including the clamp, and also optionally including the alignment collar, is also disclosed.

    Abstract translation: 包括具有凸轮表面的第一钳口构件，可相对于第一钳口构件枢转的第二钳口构件，将第一钳口构件和第二钳口构件偏压到第一位置的第一偏置构件; 以及锁定机构，该锁定机构包括用于与钳口构件的凸轮表面配合的凸轮或辊子，以及第二偏压构件，其将凸轮或辊子偏压抵靠凸轮表面以将第一钳口构件和第二钳口构件锁定在第二位置。 在夹紧之前，可以使用可选的对齐套环来对准过滤装置的部件。 还公开了包括夹具的过滤设备，并且还可选地包括对齐套环。

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