公开(公告)号：CA2896152C

公开(公告)日：2018-07-24

申请号：CA2896152

申请日：2013-12-19

Applicant: HOFFMANN LA ROCHE

Inventor： AIGNER SIMON ,  CHEMNITIUS GABRIELE ,  HORN CARINA ,  LIMBURG BERND ,  OTTENSTEIN TIMO ,  PETRICH WOLFGANG ,  PLUM MARKUS ,  RINGEMANN CHRISTIAN ,  SERR MARKUS

IPC: G01N21/77 ,  G01N21/27 ,  G01N21/84

Abstract: A method for detecting an analyte in a sample of a body fluid comprising the steps of: a) providing an optical measurement curve, which contains a plurality of measurement values recorded by monitoring a time development of a measurement value indicating a progress of a detection reaction of a test substance and the sample of a body fluid, wherein the detection reaction is known to be influenced by a set of state variables; b) providing a set of at least two different evaluation rules being adapted to derive a characteristic value from the optical measurement curve, thereby deriving a set of characteristic values X={Xi} i=1...N from the optical measurement curve; c) performing a multivariate analysis of the first and the second characteristic value by using a predetermined multivariate evaluation algorithm adapted to derive a result from at least two variables, wherein the at least one first and second characteristic value are used as the at least two variables, thereby deriving an estimate value for at least one target variable Y of the state variables; d) determining a concentration of the analyte by using the variable Y.

公开(公告)号：HK1213992A1

公开(公告)日：2016-07-15

申请号：HK16101958

申请日：2016-02-23

Applicant: HOFFMANN LA ROCHE

Inventor： AIGNER SIMON ,  CHEMNITIUS GABRIELE ,  HORN CARINA ,  LIMBURG BERND ,  OTTENSTEIN TIMO ,  PETRICH WOLFGANG ,  PLUM MARKUS ,  RINGEMANN CHRISTIAN ,  SERR MARKUS

IPC: G01N20060101

公开(公告)号：HUE034313T2

公开(公告)日：2018-02-28

申请号：HUE13811932

申请日：2013-12-19

Applicant: HOFFMANN LA ROCHE

Inventor： AIGNER SIMON ,  CHEMNITIUS GABRIELE ,  HORN CARINA ,  LIMBURG BERND ,  OTTENSTEIN TIMO ,  PETRICH WOLFGANG ,  PLUM MARKUS ,  RINGEMANN CHRISTIAN ,  SERR MARKUS

IPC: G01N21/77 ,  G01N21/27 ,  G01N21/84

公开(公告)号：HK1179146A1

公开(公告)日：2013-09-27

申请号：HK13106928

申请日：2013-06-11

Applicant: HOFFMANN LA ROCHE

Inventor： LIST HANS ,  HARTTIG HERBERT ,  AIGNER SIMON

IPC: A61B20060101

公开(公告)号：PL2936124T3

公开(公告)日：2017-08-31

申请号：PL13811932

申请日：2013-12-19

Applicant: HOFFMANN LA ROCHE

Inventor： AIGNER SIMON ,  CHEMNITIUS GABRIELE ,  HORN CARINA ,  LIMBURG BERND ,  OTTENSTEIN TIMO ,  PETRICH WOLFGANG ,  PLUM MARKUS ,  RINGEMANN CHRISTIAN ,  SERR MARKUS

IPC: G01N21/77 ,  G01N21/27 ,  G01N21/84

公开(公告)号：CA2896152A1

公开(公告)日：2014-06-26

申请号：CA2896152

申请日：2013-12-19

Applicant: HOFFMANN LA ROCHE

Inventor： AIGNER SIMON ,  CHEMNITIUS GABRIELE ,  HORN CARINA ,  LIMBURG BERND ,  OTTENSTEIN TIMO ,  PETRICH WOLFGANG ,  PLUM MARKUS ,  RINGEMANN CHRISTIAN ,  SERR MARKUS

IPC: G01N21/77 ,  G01N21/27 ,  G01N21/84

Abstract: A method for detecting an analyte in a sample of a body fluid comprising the steps of: a) providing an optical measurement curve, which contains a plurality of measurement values recorded by monitoring a time development of a measurement value indicating a progress of a detection reaction of a test substance and the sample of a body fluid, wherein the detection reaction is known to be influenced by a set of state variables; b) providing a set of at least two different evaluation rules being adapted to derive a characteristic value from the optical measurement curve, thereby deriving a set of characteristic values X={Xi} i=1...N from the optical measurement curve; c) performing a multivariate analysis of the first and the second characteristic value by using a predetermined multivariate evaluation algorithm adapted to derive a result from at least two variables, wherein the at least one first and second characteristic value are used as the at least two variables, thereby deriving an estimate value for at least one target variable Y of the state variables; d) determining a concentration of the analyte by using the variable Y.