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公开(公告)号:KR20200128105A
公开(公告)日:2020-11-11
申请号:KR20207028036
申请日:2019-03-01
Applicant: LIFE TECHNOLOGIES CORP
Inventor: MULLAH KHAIRUZZAMAN BASHAR , EVANS BRIAN , BENSON SCOTT C , CHANG CHU AN , YAN XIONGWEI
IPC: C12Q1/6818 , C09B11/24 , C12Q1/686
Abstract: 생물학적검정법에사용되는프로브가개시된다. 프로브는올리고뉴클레오티드링커를통해소광제화합물에결합된형광염료를포함한다. 또한정량적 PCR 반응 (qPCR)에서와같은예컨대중합효소연쇄반응 (PCR)용프로브를사용하는방법및 상기프로브를포함하는키트가개시된다.
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公开(公告)号:AU2019226572A1
公开(公告)日:2020-09-03
申请号:AU2019226572
申请日:2019-03-01
Applicant: LIFE TECHNOLOGIES CORP
Inventor: MULLAH KHAIRUZZAMAN BASHAR , EVANS BRIAN , BENSON SCOTT C , CHANG CHU-AN , YAN XIONGWEI
IPC: C07H21/00 , C12Q1/6818 , C12Q1/686
Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
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公开(公告)号:CA3124333A1
公开(公告)日:2020-06-25
申请号:CA3124333
申请日:2019-12-20
Applicant: LIFE TECHNOLOGIES CORP
Inventor: EVANS BRIAN , BENSON SCOTT , MULLAH KHAIRUZZAMAN BASHAR , YAN XIONGWEI
Abstract: The present invention is directed to f luorescent rhodamine dyes having spectral properties suited to the creation of multiplex assay systems for use in molecular biology, cell biology and molecular genetics. The rhodamine dyes have the following structure:
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公开(公告)号:SG11202106124UA
公开(公告)日:2021-07-29
申请号:SG11202106124U
申请日:2019-12-20
Applicant: LIFE TECHNOLOGIES CORP
Inventor: EVANS BRIAN , BENSON SCOTT , MULLAH KHAIRUZZAMAN BASHAR , YAN XIONGWEI
Abstract: The present invention is directed to fluorescent rhodamine dyes having spectral properties suited to the creation of multiplex assay systems for use in molecular biology, cell biology and molecular genetics. The rhodamine dyes have the following structure:
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公开(公告)号:CL2020002238A1
公开(公告)日:2020-12-04
申请号:CL2020002238
申请日:2020-08-31
Applicant: LIFE TECHNOLOGIES CORP
Inventor: MULLAH KHAIRUZZAMAN BASHAR , EVANS BRIAN , BENSON SCOTT C , CHANG CHU-AN , YAN XIONGWEI
IPC: C07H21/00 , C12Q1/6818 , C12Q1/686
Abstract: Se describe una sonda para su uso en ensayos biológicos. La sonda incluye un colorante fluorescente unido a un compuesto desactivador a través de un enlazador oligonucleotídico. También se describen métodos de uso de la sonda, tales como para una reacción en cadena de la polimerasa (PCR), tal como en una reacción de PCR cuantitativa (qPCR), así como kits que incluyen la sonda.
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公开(公告)号:AU2023300374A1
公开(公告)日:2025-01-16
申请号:AU2023300374
申请日:2023-06-29
Applicant: LIFE TECHNOLOGIES CORP
Inventor: SHANNON MARK , GJERSTAD CARMEN , LEONG HARRISON , ZAHEDI MOHAMMAD MEHDI , EVANS BRIAN , MULLAH KHAIRUZZAMAN BASHAR
IPC: C12Q1/6816 , C09B11/24 , C12Q1/686
Abstract: Disclosed are compositions, kits, and methods that enable intra-channel multiplexing by enabling determination of separate detectable signals, each associated with a different assay target, within the same detection channel. The multiple detectable signals can be separately resolved and independently analyzed to enable detection and/or quantification of each respective target. Enabling multiple targets to be assayed within the same detection channel increases the plexy of multiplex assays without relying on additional dyes and concomitant issues of increased spectral overlap.
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公开(公告)号:SG11202008130QA
公开(公告)日:2020-09-29
申请号:SG11202008130Q
申请日:2019-03-01
Applicant: LIFE TECHNOLOGIES CORP
Inventor: MULLAH KHAIRUZZAMAN BASHAR , EVANS BRIAN , BENSON SCOTT C , CHANG CHU-AN , YAN XIONGWEI
IPC: C07H21/00 , C12Q1/6818 , C12Q1/686
Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
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公开(公告)号:AU2019403406A1
公开(公告)日:2021-07-01
申请号:AU2019403406
申请日:2019-12-20
Applicant: LIFE TECHNOLOGIES CORP
Inventor: EVANS BRIAN , BENSON SCOTT , MULLAH KHAIRUZZAMAN BASHAR , YAN XIONGWEI
Abstract: The present invention is directed to f luorescent rhodamine dyes having spectral properties suited to the creation of multiplex assay systems for use in molecular biology, cell biology and molecular genetics. The rhodamine dyes have the following structure:
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公开(公告)号:CA3092116A1
公开(公告)日:2019-09-06
申请号:CA3092116
申请日:2019-03-01
Applicant: LIFE TECHNOLOGIES CORP
Inventor: MULLAH KHAIRUZZAMAN BASHAR , EVANS BRIAN , BENSON SCOTT C , CHANG CHU-AN , YAN XIONGWEI
IPC: C07H21/00 , C12Q1/6818 , C12Q1/686
Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
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