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    SYSTEMS AND METHODS FOR ASSIGNING ATTRIBUTES TO A PLURALITY OF SAMPLES
    1.
    发明申请
    SYSTEMS AND METHODS FOR ASSIGNING ATTRIBUTES TO A PLURALITY OF SAMPLES 审中-公开
    将属性分配给多个样本的系统和方法

    公开(公告)号：WO2012006565A3

    公开(公告)日：2012-04-19

    申请号：PCT/US2011043419

    申请日：2011-07-08

    Applicant: LIFE TECHNOLOGIES CORP ,  LEONG HARRISON ,  WU RUOYUN ,  LEE THIAM CHYE

    Inventor： LEONG HARRISON ,  WU RUOYUN ,  LEE THIAM CHYE

    IPC: G06F19/10 ,  G06F3/048 ,  G06F3/14

    CPC classification number: B01L7/52 ,  B01L3/5085 ,  B01L3/50851 ,  B01L99/00 ,  B01L2300/023 ,  B01L2300/024 ,  B01L2300/025 ,  B01L2300/027 ,  B01L2300/046 ,  B01L2300/0654 ,  B01L2300/0822 ,  B01L2300/0829 ,  G01N2035/00891

    Abstract: Systems and methods for assigning attributes to a plurality of samples are provided. An exemplary system includes an instrument configured to perform an experiment on a plurality of samples in a multi- sample support device and to produce a plurality of measured values. The system further includes a computer system in communication with the instrument. The computer system is configured to receive the plurality of measured values from the instrument, store the plurality of measured values in a memory configured as a grid of cells representing the grid of the multi- sample support device, display the grid of cells in a graphical user interface, receive a selected cell from the graphical user interface, receive two or more attribute values for the selected cell from the graphical user interface, and store the two or more assigned attribute values along with a measured value of the selected cell in the memory configured as a grid of cells.

    Abstract translation: 提供了将属性分配给多个样本的系统和方法。 示例性系统包括被配置为对多样本支持装置中的多个样本执行实验并产生多个测量值的仪器。 该系统还包括与仪器通信的计算机系统。 计算机系统被配置为从仪器接收多个测量值，将多个测量值存储在被配置为表示多样本支持设备的网格的单元格网格的存储器中，将单元格网格显示在图形中 用户界面，从图形用户界面接收所选择的单元，从图形用户界面接收所选单元格的两个或多个属性值，并将所分配的两个或更多个属性值连同选定单元格的测量值一起存储在存储器中 配置为单元格网格。

    VISUALIZATION TOOLS FOR DIGITAL PCR DATA
    2.
    发明申请
    VISUALIZATION TOOLS FOR DIGITAL PCR DATA 审中-公开
    用于数字PCR数据的可视化工具

    公开(公告)号：WO2014074735A3

    公开(公告)日：2014-08-07

    申请号：PCT/US2013068984

    申请日：2013-11-07

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： LEONG HARRISON ,  MAJUMDAR NIVEDITA SUMI ,  MARKS JEFFREY ,  STRAUB THEODORE ,  TALBOT RYAN ,  BODNER KEVIN ,  HOARD DAVID

    IPC: G06F19/26

    CPC classification number: G06T11/206 ,  G06F19/26 ,  G06T11/203

    Abstract: A method for generating a data visualization is provided. The method includes displaying a representation of a portion of detected data from a substrate to a user. The method further includes generating a data quality value for the portion of detected data and displaying, along with the representation of the portion of detected data, an indication of data quality value for the portion of detected data. The method further includes selecting, by the user, a quality value threshold, and displaying an adjusted indication of data quality value for the portion of detected data meeting the quality value threshold.

    Abstract translation: 提供了一种用于生成数据可视化的方法。 该方法包括将来自衬底的检测数据的一部分的表示显示给用户。 该方法进一步包括产生用于该部分检测数据的数据质量值，并与该部分检测数据的表示一起显示该部分检测数据的数据质量值的指示。 该方法进一步包括由用户选择质量值阈值，并显示针对满足质量值阈值的部分检测数据的数据质量值的调整指示。

    METHODS AND SYSTEMS FOR VISUALIZING DATA QUALITY
    3.
    发明专利
    METHODS AND SYSTEMS FOR VISUALIZING DATA QUALITY 未知

    公开(公告)号：CA2918243A1

    公开(公告)日：2014-12-31

    申请号：CA2918243

    申请日：2014-06-27

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： MAJUMDAR NIVEDITA SUMI ,  LEONG HARRISON ,  STRAUB THEODORE E ,  HOARD DAVID

    IPC: G16B45/00

    Abstract: A method for generating a data visualization is provided. The method includes receiving a plurality of data points related to fluorescent emissions values from a plurality of reaction sites. The fluorescent emission values include information for a first type of dye and a second type of dye. The method further includes displaying a first portion of the plurality of data points related to the first type of dye in a representation of location of the plurality of reaction sites, and displaying a second portion of the plurality of data points related to the second type of dye in the representation. The method further includes displaying the first portion of the plurality of data points in a scatter plot display. The scatter plot shows fluorescent values related to the first dye on the y-axis and fluorescent values related to the second dye on the x-axis. The method includes displaying the second portion of the plurality of data points in the scatter plot display.

    SYSTEMS AND METHODS FOR THE ANALYSIS OF PROXIMITY BINDING ASSAY DATA
    5.
    发明申请
    SYSTEMS AND METHODS FOR THE ANALYSIS OF PROXIMITY BINDING ASSAY DATA 审中-公开
    用于分析接近结合测定数据的系统和方法

    公开(公告)号：WO2012068276A3

    公开(公告)日：2012-07-19

    申请号：PCT/US2011061034

    申请日：2011-11-16

    Applicant: LIFE TECHNOLOGIES CORP ,  LEONG HARRISON ,  MAJUMDAR NIVEDITA ,  SWARTZMAN ELANA

    Inventor： LEONG HARRISON ,  MAJUMDAR NIVEDITA ,  SWARTZMAN ELANA

    IPC: G06F19/24

    CPC classification number: G06F19/18 ,  G06F19/24

    Abstract: A proximity binding assay (PBA) is performed on at least one test sample, at least one reference sample, a background sample, and one or more calibration samples using a thermal cycler instrument. Ct values are determined for at least one set of test sample data and at least one set of reference sample data. Background corrected Ct values are calculated using a corresponding value in a background sample data set. A linear range is determined for the background corrected Ct values as a function of sample quantity. A linear regression line is calculated for each linear range. One or more parameter values of an exponential model (EM) fold change formula are estimated from the one or more sets of calibration sample data. A target protein quantity and associated confidence interval are calculated using the linear regression lines and the EM fold change formula.

    Abstract translation: 使用热循环仪器在至少一个测试样品，至少一个参考样品，背景样品和一个或多个校准样品上进行接近结合测定（PBA）。 对至少一组测试样本数据和至少一组参考样本数据确定Ct值。 背景校正的Ct值是使用背景样本数据集中的对应值计算的。 根据样品数量确定背景校正Ct值的线性范围。 针对每个线性范围计算线性回归线。 根据一组或多组校准样本数据估计指数模型（EM）倍数变化公式的一个或多个参数值。 使用线性回归线和EM倍数变化公式计算目标蛋白质量和相关置信区间。

    Methods and systems for visualizing data quality
    6.
    发明专利
    Methods and systems for visualizing data quality 未知

    公开(公告)号：AU2014302101A1

    公开(公告)日：2016-02-04

    申请号：AU2014302101

    申请日：2014-06-27

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： MAJUMDAR NIVEDITA SUMI ,  LEONG HARRISON ,  STRAUB THEODORE E ,  HOARD DAVID

    IPC: G16B45/00

    Abstract: A method for generating a data visualization is provided. The method includes receiving a plurality of data points related to fluorescent emissions values from a plurality of reaction sites. The fluorescent emission values include information for a first type of dye and a second type of dye. The method further includes displaying a first portion of the plurality of data points related to the first type of dye in a representation of location of the plurality of reaction sites, and displaying a second portion of the plurality of data points related to the second type of dye in the representation. The method further includes displaying the first portion of the plurality of data points in a scatter plot display. The scatter plot shows fluorescent values related to the first dye on the y-axis and fluorescent values related to the second dye on the x-axis. The method includes displaying the second portion of the plurality of data points in the scatter plot display.

    Visualization tools for digital PCR data
    7.
    发明专利
    Visualization tools for digital PCR data 未知

    公开(公告)号：AU2013341089A1

    公开(公告)日：2015-06-18

    申请号：AU2013341089

    申请日：2013-11-07

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： LEONG HARRISON ,  MAJUMDAR NIVEDITA SUMI ,  MARKS JEFFREY ,  STRAUB THEODORE ,  TALBOT RYAN ,  BODNER KEVIN ,  HOARD DAVID

    IPC: G16B45/00

    Abstract: A method for generating a data visualization is provided. The method includes displaying a representation of a portion of detected data from a substrate to a user. The method further includes generating a data quality value for the portion of detected data and displaying, along with the representation of the portion of detected data, an indication of data quality value for the portion of detected data. The method further includes selecting, by the user, a quality value threshold, and displaying an adjusted indication of data quality value for the portion of detected data meeting the quality value threshold.

    SYSTEMS AND METHODS FOR ANALYTE DETECTION FROM MULTIPLEXED ASSAYS
    10.
    发明专利
    SYSTEMS AND METHODS FOR ANALYTE DETECTION FROM MULTIPLEXED ASSAYS 未知

    公开(公告)号：AU2023298557A1

    公开(公告)日：2025-01-16

    申请号：AU2023298557

    申请日：2023-06-29

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： SHANNON MARK ,  GJERSTAD CARMEN ,  LEONG HARRISON

    IPC: C12Q1/6816 ,  G16B25/20

    Abstract: Systems and methods that enable analyte detection in a multiplexed amplification process can include obtaining, at multiple time points during the amplification process, composite emission signal data associated with a composite emission signal from at least a first probe type comprising a first label configured to generate a first emission signal and a second probe type comprising a second label configured to generate a second emission signal which has spectrally similar characteristics as said first emission signal, the first probe type and the second probe type differing in thermal and/or temporal properties; and determining, based at least partially on the composite emission signal data, emission signal data associated with a emission signal from a given probe type of the first probe type or the second probe type during the amplification process.

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