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公开(公告)号：WO2011013011A3
公开(公告)日：2011-06-23
申请号：PCT/IB2010002310
申请日：2010-07-19
Applicant: MAUNA KEA TECHNOLOGIES , BOULAROT NICOLAS , CRESSANT ARNAUD
Inventor： BOULAROT NICOLAS , CRESSANT ARNAUD
CPC classification number: A61B5/0084 , A61B1/00154 , A61B1/313 , A61B5/0068 , A61B5/0071 , A61B5/6814 , A61B5/6864 , A61B5/6868 , A61B5/6882 , A61B90/11 , A61B2503/40 , A61B2560/063 , A61B2562/0238 , G02B23/26
Abstract: An intracranial implant to position a fiber bundle to a specified region of a brain of an animal. The implant may include a base support to be fixed to a skull of the animal over an orifice drilled in the skull, a hollow conduit arranged through the base support to guide the fiber bundle to the brain of the animal through the drilled orifice and a first locking member arranged on the base support, to cooperate with a ferrule of the fiber bundle, the first locking member configured to lock the fiber bundle to the specified region of the brain of the animal.
Abstract translation: 将颅内植入物定位于动物脑的特定区域的纤维束。 植入物可以包括在头部钻孔的孔上固定到动物颅骨的基部支撑件，布置成穿过基部支撑件的中空导管，以通过钻孔将纤维束引导到动物的大脑，第一 锁定构件，其布置在所述基部支撑件上，以与所述纤维束的套圈配合，所述第一锁定构件配置成将所述纤维束锁定到所述动物的脑的特定区域。
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2.发明申请MODULAR IMAGING DEVICE, MODULE FOR THIS DEVICE, AND METHOD OF IMPLEMENTATION BY THIS DEVICE 审中-公开模块化成像装置，用于该装置的模块以及由该装置执行的方法
公开(公告)号：WO2009053632A3
公开(公告)日：2009-06-25
申请号：PCT/FR2008051845
申请日：2008-10-10
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： VIELLEROBE BERTRAND , LACOMBE FRANCOIS , BOULAROT NICOLAS , DOUSSOUX FRANCOIS , LAVILLONNIERE NICOLAS
CPC classification number: G01N21/6458 , A61B1/00165 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/07 , A61B5/0068 , A61B5/0071 , A61B5/0084 , G01N2021/6419 , G01N2021/6421 , G01N2201/024 , G01N2201/0846 , G01N2201/086
Abstract: The present invention relates to an imaging device comprising: an illumination module (1) comprising means for emitting at least one excitation beam; a scanning/injection module (2) comprising an image waveguide (3), the two ends of which, the proximal end (3a) and the distal end (3b) respectively, are connected via a plurality of optical fibres, and scanning/injection means (6) designed to inject the at least one excitation beam in turn into a fibre of the image waveguide (3) and then into the proximal side (3a) of said waveguide and a detection module (4) comprising means for detecting a light flux (14) collected at the distal end (3b) of the waveguide. At least either the illumination module (1) or the detection module (4) is optically conjugate with the scanning/injection module (2) via a conjugating optical fibre (5, 7). The use of conjugating fibres (5, 7) enables the maintenance, repair and updating of the device to be improved. It also enables modal filtering of the excitation beam to be carried out and ensures that the device is confocal.
Abstract translation: 本发明涉及一种成像装置，其包括：照明模块（1），其包括用于发射至少一个激发光束的装置; 包括图像波导（3）的扫描/注射模块（2），所述图像波导（3）的两端分别通过多根光纤连接所述近端（3a）和所述远端（3b），并且扫描/注入 被设计成将所述至少一个激励光束依次注入到所述图像波导（3）的光纤中并且然后注入到所述波导的近侧（3a）中的装置（6）;以及检测模块（4），其包括用于检测光 通量（14）收集在波导的远端（3b）处。 照明模块（1）或检测模块（4）中的至少一个经由共轭光纤（5,7）与扫描/注射模块（2）光学共轭。 共轭纤维（5,7）的使用使得设备的维护，修理和更新得以改善。 它还可以对激发光束进行模态滤波，确保设备共焦。
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公开(公告)号：WO2013153448A3
公开(公告)日：2013-12-05
申请号：PCT/IB2013001024
申请日：2013-04-08
Applicant: MAUNA KEA TECHNOLOGIES , ENDOCONTROL , UNIV PARIS CURIE , CENTRE NAT RECH SCIENT
Inventor： ERDEN MUSTAFA SUPHI , ROSA BENOIT , SZEWCZYK JEROME , MOREL GUILLAUME , VIDAL CLEMENT , HENRI PATRICK , BOULAROT NICOLAS
CPC classification number: A61B1/0057 , A61B1/00133 , A61B1/00165 , A61B1/00172 , A61B5/0062 , A61B5/0068 , A61B5/0084 , G02B6/0008 , G02B6/04 , G02B2006/0098
Abstract: In at least one aspect, embodiments disclosed herein relate to a miniaturized scanning system to generate movement of a flexible device positioned at a distal part of a medical tool. The miniaturized scanning system comprises: an inner shaft with a longitudinal axis, adapted to guide said flexible device along said longitudinal axis, an abutment comprising an external surface and adapted to maintain said device, a pusher mechanism adapted to engage with said abutment and comprising at least one end portion adapted to contact said external surface of the abutment at a contact point, wherein said end portion is configured to translate along said longitudinal axis of the inner shaft and wherein the translation of said end portion results in a bending of the device in a bending plane defined by the longitudinal axis of the inner shaft and said contact point.
Abstract translation: 在至少一个方面，本文公开的实施例涉及一种小型化扫描系统，用于产生位于医疗工具的远端部分的柔性装置的运动。 小型化扫描系统包括：具有纵向轴线的内轴，其适于沿着所述纵向轴线引导所述柔性装置，包括外表面并适于保持所述装置的支座，适于与所述基座接合的推动器机构， 适于在接触点处接触所述邻接件的所述外表面的至少一个端部部分，其中所述端部部分构造成沿着所述内轴的所述纵向轴线平移，并且其中所述端部部分的平移导致所述装置的弯曲 由所述内轴和所述接触点的纵向轴线限定的弯曲平面。
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4.发明申请USE OF A SYSTEM FOR IMAGING BY FIBER-OPTIC CONFOCAL FLUORESCENCE IN VIVO IN SITU, SYSTEM AND METHOD FOR IMAGING BY FIBER-OPTIC CONFOCAL FLUORESCENCE IN VIVO IN SITU 审中-公开体内光纤共焦荧光原位成像系统的应用，原位纤维 - 光学共焦荧光成像系统和方法的应用
公开(公告)号：WO2008020130A3
公开(公告)日：2008-04-10
申请号：PCT/FR2007001371
申请日：2007-08-16
Applicant: MAUNA KEA TECHNOLOGIES , UNIV ROUEN , THIBERVILLE LUC , CAVE CHARLOTTE , DENTAN VERONIQUE , BOULAROT NICOLAS , BOURG-HECKLY GENEVIEVE , PELTIER ERIC
Inventor： THIBERVILLE LUC , CAVE CHARLOTTE , DENTAN VERONIQUE , BOULAROT NICOLAS , BOURG-HECKLY GENEVIEVE , PELTIER ERIC
IPC: A61B5/00
CPC classification number: A61B1/2676 , A61B1/00165 , A61B1/018 , A61B1/043 , A61B1/2736 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/0084
Abstract: The present invention relates to a novel use of a system for imaging by fiber-optic confocal fluorescence in vivo in situ, comprising a fiber-optic probe for imaging a tissue or an alveolus situated distant from the distal vision of a bronchial endoscope. The present invention also relates to a system for imaging by fluorescence in vivo, comprising an endoscope equipped with an operator channel comprising a fiber-optic probe (20) that can be moved longitudinally between a retracted position and at least one position of extension outside the endoscope. The probe (20) also comprises graduations for evaluation of the distal end (21) of the probe (20). The imaging system according to the invention can also be provided with an intermediate catheter receiving the fiber-optic probe and inserted in an endoscope. This intermediate catheter ensures anchoring on biological tissue and also aspiration of biological material.
Abstract translation: 本发明涉及用于通过原位体内光纤共聚焦荧光成像的系统的新用途，其包括用于成像远离支气管内窥镜的远端视野定位的组织或肺泡的光纤探针。 本发明还涉及一种通过体内荧光进行成像的系统，包括配备有操作员通道的内窥镜，所述操作员通道包括光纤探针（20），所述光纤探针（20）可以在缩回位置和所述至少一个延伸位置之间纵向移动， 内窥镜。 探针（20）还包括用于评估探针（20）的远端（21）的刻度。 根据本发明的成像系统还可以设置有接收光纤探针并插入内窥镜中的中间导管。 该中间导管可确保锚定在生物组织上并吸引生物材料。
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公开(公告)号：AU2010277231A2
公开(公告)日：2012-03-22
申请号：AU2010277231
申请日：2010-07-19
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： BOULAROT NICOLAS , CRESSANT ARNAUD
Abstract: An intracranial implant to position a fiber bundle to a specified region of a brain of an animal. The implant may include a base support to be fixed to a skull of the animal over an orifice drilled in the skull, a hollow conduit arranged through the base support to guide the fiber bundle to the brain of the animal through the drilled orifice and a first locking member arranged on the base support, to cooperate with a ferrule of the fiber bundle, the first locking member configured to lock the fiber bundle to the specified region of the brain of the animal.
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Patent Agency Ranking
公开(公告)号：CA2701993A1
公开(公告)日：2009-04-30
申请号：CA2701993
申请日：2008-10-10
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： VIELLEROBE BERTRAND , LACOMBE FRANCOIS , BOULAROT NICOLAS , DOUSSOUX FRANCOIS , LAVILLONNIERE NICOLAS
Abstract: La présente invention concerne un dispositif d'imagerie, comprenant: un module d'illumination (1) comprenant des moyens pour émettre au moins un faisceau d'excitation; un module de balayage et d'injection (2) comprenant un guide d'image (3) dont deux extrémités respectivement proximale (3a) et distale (3b) sont reliées par une pluralité de fibres optiques, et des moyens (6) de balayage et d'injection agencés pour injecter l'au moins un faisceau d'excitation tour à tour dans une fibre du guide d'image (3) et du côté proximal (3a) du guide; un module de détection (4) comprenant des moyens pour détecter un flux lumineux (14) collecté à l'extrémité distale (3b) du guide. Au moins un parmi le module d'illumination (1) et le module de détection (4) est conjugué optiquement au module de balayage et d'injection (2) par une fibre optique de conjugaison (5, 7). L'utilisation de fibres de conjugaison (5, 7) permet d'améliorer la maintenance, la réparation et la mise à jour du dispositif, et peut en outre permettre de réaliser un filtrage modal du faisceau d'excitation et d'assurer la confocalité du dispositif.
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公开(公告)号：FR2900741A1
公开(公告)日：2007-11-09
申请号：FR0604019
申请日：2006-05-05
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor： GENET MAGALIE , MATHIEU GILLES , VIELLEROBE BERTRAND , DOUSSOUX FRANCOIS , BOULAROT NICOLAS , LAVILLONNIERE NICOLAS
Abstract: L'invention concerne une tête optique miniaturisée prévue pour équiper l'extrémité distale d'un faisceau de fibres optiques souples balayé par un faisceau laser, ladite tête optique étant destinée à venir au contact d'un échantillon et exciter ledit échantillon de manière confocale ; cette tête optique comprenant des moyens de correction des aberrations sphériques et des moyens de focalisation. Selon l'invention, les moyens de focalisation comprennent :- au moins une première lentille (L4) de forte convergence associée à une lentille (L5) boule ou demi-boule disposée à l'extrémité distale de la tête optique, et- des moyens de correction du chromatisme axial et latéral pourvus d'une unique lentille divergente (3b) dont la courbure est sensiblement centrée sur la pupille du faisceau de fibres optiques et disposée à la juste distance de cette pupille pour laquelle les conditions d'achromatisation latérale coïncident avec les conditions d'achromatisation axiale; cette lentille divergente étant associée à une seconde lentille convergente (L3a) sous forme d'un doublet (L3).
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公开(公告)号：CA2754863C
公开(公告)日：2015-11-17
申请号：CA2754863
申请日：2010-03-12
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： ROCHER ALEXANDRA , DOUSSOUX FRANCOIS , CLADE SOPHIE , PETIT SYLVAIN , BOULAROT NICOLAS
Abstract: A connector to connect a fiber bundle probe to a light injection module including a tightening cam having an opening of a specified shape adapted to receive the fiber bundle probe, a cam driving coupled to the tightening cam, wherein the tightening cam is configured to translate in response to rotation of the cam driving until the tightening cam is blocked, at least one spring extending between the tightening cam and the cam driving, wherein the at least one spring is configured to resist when the cam driving is actuated by rotation and the tightening cam is blocked, and a locking mechanism to lock the cam driving into a selected position.
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9.发明专利
公开(公告)号：FR2901029B1
公开(公告)日：2012-12-21
申请号：FR0604259
申请日：2006-05-12
Applicant: MAUNA KEA TECHNOLOGIES
Inventor： LACOMBE FRANCOIS , VIELLEROBE BERTRAND , BOULAROT NICOLAS , DOUSSOUX FRANCOIS , PERCHANT AYMERIC
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10.发明专利
公开(公告)号：FR2922308B1
公开(公告)日：2012-03-16
申请号：FR0758236
申请日：2007-10-11
Applicant: MAUNA KEA TECHNOLOGIES
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