公开(公告)号：AU2019243943A1

公开(公告)日：2020-10-15

申请号：AU2019243943

申请日：2019-03-27

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAN MD RAUFUL ,  AMEDZO LUKIANA ,  BABU SURESH ,  BAIAZITOV RAMIL Y ,  BARRAZA SCOTT J ,  BHATTACHARYYA ANURADHA ,  KARP GARY MITCHELL ,  KENTON NATHANIEL T ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MSZAR NICHOLAS W ,  NARASIMHAN JANA ,  PAL SUDIPTA ,  PATEL JIGAR S ,  TURPOFF ANTHONY ,  WOLL MATHEW G ,  XU ZHENRONG ,  ZHANG NANJING

IPC: A61K31/395 ,  A61K31/53 ,  A61K47/10 ,  C07D251/12 ,  C07D251/16 ,  C07D401/02

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：CA3094700A1

公开(公告)日：2019-10-03

申请号：CA3094700

申请日：2019-03-27

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  AMEDZO LUKIANA ,  BABU SURESH ,  BAIAZITOV RAMIL Y ,  BARRAZA SCOTT J ,  BHATTACHARYYA ANURADHA ,  KARP GARY MITCHELL ,  KENTON NATHANIEL T ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MSZAR NICHOLAS W ,  NARASIMHAN JANA ,  PAL SUDIPTA ,  PATEL JIGAR S ,  TURPOFF ANTHONY ,  WOLL MATHEW G ,  XU ZHENRONG ,  ZHANG NANJING ,  ALAM RAUFUL

IPC: A61K31/395 ,  A61K31/53 ,  A61K47/10 ,  C07D251/12 ,  C07D251/16 ,  C07D401/02

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.