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公开(公告)号：FI3814357T3
公开(公告)日：2024-07-26
申请号：FI19736566
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC , PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：HRP20240935T1
公开(公告)日：2024-11-22
申请号：HRP20240935
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
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公开(公告)号：AU2019294482B2
公开(公告)日：2022-09-01
申请号：AU2019294482
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： ZHANG NANJING , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , CHEN GUANGMING , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , SYDORENKO NADIYA , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING
IPC: C07D417/14 , A61K31/4439 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5025 , A61K31/519 , A61K31/55 , A61P25/00 , A61P25/14 , A61P25/28 , C07D471/04 , C07D487/04 , C07D513/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted benzothiazole compounds of Formula (I) or (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：AU2022209304A1
公开(公告)日：2022-08-25
申请号：AU2022209304
申请日：2022-07-28
Applicant: PTC THERAPEUTICS INC
Inventor： ZHANG NANJING , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , CHEN GUANGMING , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , SYDORENKO NADIYA , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING
IPC: C07D417/14 , A61K31/4439 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5025 , A61K31/519 , A61K31/55 , A61P25/00 , A61P25/14 , A61P25/28 , C07D471/04 , C07D487/04 , C07D513/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. W3 R2 R 3 X (I) (II) In particular, the present description relates to substituted benzothiazole compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：SG11202112504YA
公开(公告)日：2021-12-30
申请号：SG11202112504Y
申请日：2020-05-12
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , AMEDZO LUKIANA , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , LUONG TOM TUAN , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MORRILL CHRISTIE , NARASIMHAN JANA , MSZAR NICHOLAS WALTER , PATEL JIGAR S , REN HONGYU , TURPOFF ANTHONY , WANG GANG , WOLL MATTHEW G , ZHANG NANJING , ZHANG XIAOYAN
IPC: C07D401/14 , A61K31/501 , A61K31/53 , A61P25/28 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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Patent Agency Ranking
公开(公告)号：CA3094700A1
公开(公告)日：2019-10-03
申请号：CA3094700
申请日：2019-03-27
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , AMEDZO LUKIANA , BABU SURESH , BAIAZITOV RAMIL Y , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MSZAR NICHOLAS W , NARASIMHAN JANA , PAL SUDIPTA , PATEL JIGAR S , TURPOFF ANTHONY , WOLL MATHEW G , XU ZHENRONG , ZHANG NANJING , ALAM RAUFUL
IPC: A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：BRPI0511834A
公开(公告)日：2008-01-08
申请号：BRPI0511834
申请日：2005-07-14
Applicant: PTC THERAPEUTICS INC
Inventor： HWANG PETER SEONGWOO , TAKASUGI JAMES , REN HONGYU , WILDE RICHARD GERALD , TURPOFF ANTHONY , AREFOLOV ALEXANDER , KARP GARY MITCHELL , CHEN GUANGMING , CAMPBELL JEFFREY ALLEN
IPC: A61K31/404 , A61P31/14
Abstract: In accordance with the present invention, compounds that inhibit viral replication, preferably Hepatitis C Virus (HCV) replication, have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the treatment or prevention of a viral infection are provided. In another aspect of the invention, compounds useful in the treatment or prevention of HCV infection are provided.
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公开(公告)号：ECSP077252A
公开(公告)日：2007-05-30
申请号：ECSP077252
申请日：2007-02-14
Applicant: PTC THERAPEUTICS INC
Inventor： HWANG PETER SEONGWOO , TAKASUGI JAMES , REN HONGYU , WILDE RICHARD GERALD , TURPOFF ANTHONY , AREFOLOV ALEXANDER , KARP GARY MITCHELL , CHEN GUANGMING , CAMPBELL JEFFREY ALLEN
IPC: A61K31/404
Abstract: De acuerdo con la presente invención, los compuestos que inhiben la replicación viral, preferiblemente, la replicación del virus de la Hepatitis C (HCV), han sido identificados, y los métodos para su uso provistos. En un aspecto de la invención, los compuestos empleados en el tratamiento o prevención de una infección viral están provistos. En otro aspecto de la invención, los compuestos empleados en el tratamiento o prevención de la infección por HCV están provistos.
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公开(公告)号：AU2023203241B2
公开(公告)日：2025-01-02
申请号：AU2023203241
申请日：2023-05-23
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. Formula (I). In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：PL3814357T3
公开(公告)日：2024-09-16
申请号：PL19736566
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
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