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公开(公告)号:AU2018282154B2
公开(公告)日:2022-04-07
申请号:AU2018282154
申请日:2018-06-05
Applicant: PTC THERAPEUTICS INC
Inventor: WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:AU2018282154A1
公开(公告)日:2020-01-02
申请号:AU2018282154
申请日:2018-06-05
Applicant: PTC THERAPEUTICS INC
Inventor: WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:AU2019294482A1
公开(公告)日:2021-01-21
申请号:AU2019294482
申请日:2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor: ZHANG NANJING , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , CHEN GUANGMING , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , SYDORENKO NADIYA , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING
IPC: C07D417/14 , A61K31/4439 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5025 , A61K31/519 , A61K31/55 , A61P25/00 , A61P25/14 , A61P25/28 , C07D471/04 , C07D487/04 , C07D513/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted benzothiazole compounds of Formula (I) or (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:CA3104516A1
公开(公告)日:2020-01-02
申请号:CA3104516
申请日:2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor: ZHANG NANJING , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , CHEN GUANGMING , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , SYDORENKO NADIYA , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING
IPC: C07D417/14 , A61K31/4439 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5025 , A61K31/519 , A61K31/55 , A61P25/00 , A61P25/14 , A61P25/28 , C07D471/04 , C07D487/04 , C07D513/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted benzothiazole compounds of Formula (I) or (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:CA3066224A1
公开(公告)日:2018-12-13
申请号:CA3066224
申请日:2018-06-05
Applicant: PTC THERAPEUTICS INC
Inventor: WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:MX2020009956A
公开(公告)日:2021-01-15
申请号:MX2020009956
申请日:2019-03-27
Applicant: PTC THERAPEUTICS INC
Inventor: WOLL MATTHEW G , NARASIMHAN JANA , ZHANG NANJING , KARP GARY MITCHELL , SYDORENKO NADIYA , BABU SURESH , BHATTACHARYYA ANURADHA , BARRAZA SCOTT J , MAZZOTTI ANTHONY R , TURPOFF ANTHONY , XU ZHENRONG , MOON YOUNG-CHOON , PATEL JIGAR S , ALAM MD RAUFUL , AMEDZO LUKIANA , BAIAZITOV RAMIL Y , KENTON NATHANIEL T , MSZAR NICHOLAS W , PAL SUDIPTA
IPC: A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
Abstract: La descripción actual se refiere a compuestos, formas, y composiciones farmacéuticas de los mismos y métodos para usar tales compuestos, formas, o composiciones de los mismos para el tratamiento o aminoración de la enfermedad de Huntington. (ver Fórmulas) En particular, la descripción actual se refiere a compuestos heteroarilo monocíclicos sustituidos de la Fórmula (I) o Fórmula (II), formas y composiciones farmacéuticas de los mismos y métodos para usar tales compuestos, formas, o composiciones de los mismos para el tratamiento o aminoración de la enfermedad de Hungtinton.
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公开(公告)号:AU2019243943A1
公开(公告)日:2020-10-15
申请号:AU2019243943
申请日:2019-03-27
Applicant: PTC THERAPEUTICS INC
Inventor: SYDORENKO NADIYA , ALAN MD RAUFUL , AMEDZO LUKIANA , BABU SURESH , BAIAZITOV RAMIL Y , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MSZAR NICHOLAS W , NARASIMHAN JANA , PAL SUDIPTA , PATEL JIGAR S , TURPOFF ANTHONY , WOLL MATHEW G , XU ZHENRONG , ZHANG NANJING
IPC: A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:AU2022201299A1
公开(公告)日:2022-03-24
申请号:AU2022201299
申请日:2022-02-25
Applicant: PTC THERAPEUTICS INC
Inventor: WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. ,W1 W2 R2 W6 2~ (I) In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:SG11202012869SA
公开(公告)日:2021-01-28
申请号:SG11202012869S
申请日:2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor: ZHANG NANJING , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , CHEN GUANGMING , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , SYDORENKO NADIYA , TURPOFF ANTHONY , WOLL MATTHEW , YAN WUMING
IPC: C07D417/14 , A61K31/4439 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5025 , A61K31/519 , A61K31/55 , A61P25/00 , A61P25/14 , A61P25/28 , C07D471/04 , C07D487/04 , C07D513/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted benzothiazole compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号:AU2019294482B2
公开(公告)日:2022-09-01
申请号:AU2019294482
申请日:2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor: ZHANG NANJING , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , CHEN GUANGMING , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , SYDORENKO NADIYA , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING
IPC: C07D417/14 , A61K31/4439 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5025 , A61K31/519 , A61K31/55 , A61P25/00 , A61P25/14 , A61P25/28 , C07D471/04 , C07D487/04 , C07D513/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted benzothiazole compounds of Formula (I) or (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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