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公开(公告)号：AU2018282154B2
公开(公告)日：2022-04-07
申请号：AU2018282154
申请日：2018-06-05
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：AU2018282154A1
公开(公告)日：2020-01-02
申请号：AU2018282154
申请日：2018-06-05
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：AU2022201299A1
公开(公告)日：2022-03-24
申请号：AU2022201299
申请日：2022-02-25
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. ,W1 W2 R2 W6 2~ (I) In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：BR112021022624A2
公开(公告)日：2022-01-04
申请号：BR112021022624
申请日：2020-05-12
Applicant: PTC THERAPEUTICS INC
Inventor： TURPOFF ANTHONY , ANTHONY R MAZZOTTI , BHATTACHARYYA ANURADHA , MORRILL CHRISTIE , WANG GANG , GARY MITCHELL KARP , REN HONGYU , NARASIMHAN JANA , JIGAR S PATEL , AMEDZO LUKIANA , MATTHEW G WOLL , MD RAUFUL ALAM , MICHAEL A ARNOLD , SYDORENKO NADIYA , ZHANG NANJING , NATHANIEL T KENTON , NICHOLAS W MSZAR , BABU SURESH , TOM TUAN LUONG , ZHANG XIAOYAN , MOON YOUNG-CHOON
IPC: A61K31/53 , A61K31/501 , A61P25/28 , C07D401/14 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: compostos para o tratamento da doença de huntington. a presente invenção refere-se a compostos, formas, e composições farmacêuticas dos mesmos e métodos de uso de tais compostos, formas, ou composições dos mesmos para tratar ou melhorar a doença de huntington. em particular, a presente descrição refere-se a compostos heteroarila monocíclicos substituídos de fórmula (i), fórmula (ii), ou fórmula (iii), formas e composições farmacêuticas dos mesmos e métodos de uso de tais compostos, formas, ou composições dos mesmos para tratar ou melhorar a doença de huntington.
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公开(公告)号：AU2020277027A1
公开(公告)日：2021-12-09
申请号：AU2020277027
申请日：2020-05-12
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , AMEDZO LUKIANA , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , LUONG TOM TUAN , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MORRILL CHRISTIE , MSZAR NICHOLAS WALTER , NARASIMHAN JANA , PATEL JIGAR S , REN HONGYU , TURPOFF ANTHONY , WANG GANG , WOLL MATTHEW G , ZHANG NANJING , ZHANG XIAOYAN
IPC: C07D401/14 , A61K31/501 , A61K31/53 , A61P25/28 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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Patent Agency Ranking
公开(公告)号：SG11201911615WA
公开(公告)日：2020-01-30
申请号：SG11201911615W
申请日：2018-06-05
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT , BHATTACHARYYA ANURADHA , KARP GARY , MAZZOTTI ANTHONY , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：CA3066224A1
公开(公告)日：2018-12-13
申请号：CA3066224
申请日：2018-06-05
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：SG11202112504YA
公开(公告)日：2021-12-30
申请号：SG11202112504Y
申请日：2020-05-12
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , AMEDZO LUKIANA , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , LUONG TOM TUAN , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MORRILL CHRISTIE , NARASIMHAN JANA , MSZAR NICHOLAS WALTER , PATEL JIGAR S , REN HONGYU , TURPOFF ANTHONY , WANG GANG , WOLL MATTHEW G , ZHANG NANJING , ZHANG XIAOYAN
IPC: C07D401/14 , A61K31/501 , A61K31/53 , A61P25/28 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：CA3094700A1
公开(公告)日：2019-10-03
申请号：CA3094700
申请日：2019-03-27
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , AMEDZO LUKIANA , BABU SURESH , BAIAZITOV RAMIL Y , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , KENTON NATHANIEL T , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , MSZAR NICHOLAS W , NARASIMHAN JANA , PAL SUDIPTA , PATEL JIGAR S , TURPOFF ANTHONY , WOLL MATHEW G , XU ZHENRONG , ZHANG NANJING , ALAM RAUFUL
IPC: A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：MX2020009956A
公开(公告)日：2021-01-15
申请号：MX2020009956
申请日：2019-03-27
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW G , NARASIMHAN JANA , ZHANG NANJING , KARP GARY MITCHELL , SYDORENKO NADIYA , BABU SURESH , BHATTACHARYYA ANURADHA , BARRAZA SCOTT J , MAZZOTTI ANTHONY R , TURPOFF ANTHONY , XU ZHENRONG , MOON YOUNG-CHOON , PATEL JIGAR S , ALAM MD RAUFUL , AMEDZO LUKIANA , BAIAZITOV RAMIL Y , KENTON NATHANIEL T , MSZAR NICHOLAS W , PAL SUDIPTA
IPC: A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
Abstract: La descripción actual se refiere a compuestos, formas, y composiciones farmacéuticas de los mismos y métodos para usar tales compuestos, formas, o composiciones de los mismos para el tratamiento o aminoración de la enfermedad de Huntington. (ver Fórmulas) En particular, la descripción actual se refiere a compuestos heteroarilo monocíclicos sustituidos de la Fórmula (I) o Fórmula (II), formas y composiciones farmacéuticas de los mismos y métodos para usar tales compuestos, formas, o composiciones de los mismos para el tratamiento o aminoración de la enfermedad de Hungtinton.
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