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公开(公告)号：EP3043815A4
公开(公告)日：2017-06-14
申请号：EP14844704
申请日：2014-09-11
Applicant: STC UNM , LEIDOS INC
Inventor： PEABODY DAVID S , CHACKERIAN BRYCE , PANNUCCI JAMES , GUTIERREZ GABRIEL M , NOE AMY RENE , WINRAM SCOTT BUDD , HUANG STEVE CHIENWEN
CPC classification number: A61K39/015 , A61K35/76 , A61K39/39 , A61K2039/5256 , A61K2039/5258 , A61K2039/55566 , C07K2319/40 , C12N7/00 , C12N15/1037 , C12N2795/18122 , C12N2795/18123 , C12N2795/18134
Abstract: Embodiments are directed to malaria vaccines comprising a bacteriophage VLP displaying a heterologous peptide identified by affinity selection as an anti-malaria mimotope.
Abstract translation: 实施方案涉及包含展示通过亲和选择鉴定的异源肽作为抗疟疾模拟表位的噬菌体VLP的疟疾疫苗。
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公开(公告)号：AU2018273958A1
公开(公告)日：2020-01-02
申请号：AU2018273958
申请日：2018-05-25
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PHARES TIMOTHY , PANNUCCI JAMES
IPC: C07K14/705 , A61K38/17
Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 as well as the interaction of CTLA4 with CD86 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.
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公开(公告)号：AU2018410849B2
公开(公告)日：2025-02-27
申请号：AU2018410849
申请日：2018-02-28
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PANNUCCI JAMES , AYALA RAMSES
IPC: A61K38/10 , A61K38/16 , A61K48/00 , A61P17/00 , A61P17/02 , A61P31/00 , A61P31/04 , A61P35/00 , A61Q5/00 , A61Q19/02 , C12N15/00
Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor programmed death 1 (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.
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公开(公告)号：AU2017325866B2
公开(公告)日：2021-09-09
申请号：AU2017325866
申请日：2017-09-15
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PANNUCCI JAMES , AYALA RAMSES
Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PDL1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.
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公开(公告)号：CA3141162A1
公开(公告)日：2020-11-26
申请号：CA3141162
申请日：2020-05-21
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PHARES TIMOTHY W , PANNUCCI JAMES , MANSOUR MARC
IPC: C07K7/08 , A61K38/17 , A61P35/00 , C07K14/00 , C07K14/705 , C07K19/00 , C12N5/10 , C12N7/01 , C12N15/62
Abstract: This disclosure provides peptides which bind to LAG3 and can be used to block the interaction of LAG 3 with other molecules such as MHC-II, FGL1, and a-synuclein. These peptides can be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, or inhibiting the progression of a synucleinopathy, inhibiting the progression of sepsis, inhibiting the progression of an infectious disease, and enhancing a response to a vaccine.
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Patent Agency Ranking
公开(公告)号：CA3036251A1
公开(公告)日：2018-03-22
申请号：CA3036251
申请日：2017-09-15
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PANNUCCI JAMES , AYALA RAMSES
Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PDL1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.
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公开(公告)号：DK3758732T3
公开(公告)日：2024-10-07
申请号：DK18712047
申请日：2018-02-28
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PANNUCCI JAMES , AYALA RAMSES
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公开(公告)号：DK3795167T3
公开(公告)日：2022-08-29
申请号：DK20204314
申请日：2017-09-15
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PANNUCCI JAMES , AYALA RAMSES
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公开(公告)号：AU2018273958B2
公开(公告)日：2022-07-21
申请号：AU2018273958
申请日：2018-05-25
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , KOTRAIAH VINAYAKA , PHARES TIMOTHY , PANNUCCI JAMES
IPC: A61K38/17 , C07K14/705
Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 as well as the interaction of CTLA4 with CD86 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.
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公开(公告)号：DK3512536T3
公开(公告)日：2020-11-23
申请号：DK17778394
申请日：2017-09-15
Applicant: LEIDOS INC
Inventor： GUTIERREZ GABRIEL M , PANNUCCI JAMES , AYALA RAMSES , KOTRAIAH VINAYAKA
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