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公开(公告)号：ES2229664T3
公开(公告)日：2005-04-16
申请号：ES99900324
申请日：1999-01-14
Applicant: TORAY INDUSTRIES
Inventor： MURAKAMI MUTSUO , TATEISHI YASUSHI , FUSAOKA YOSHINARI
Abstract: Membrana semipermeable composite que se caracteriza por el hecho de que la membrana semipermeable composite: (a) tiene una membrana de soporte microporoso sobre la que se forma una capa de membrana ultrafina de poliamida reticulada que proviene, mediante policondensación, de una amina polifuncional, de un haluro de ácido polifuncional y de un derivado de ácido polifuncional que tiene grupos de anhídrido de ácido y de haluro de ácido, dicha capa de membrana ultrafina tiene una concentración de grupos carboxilo, analizada por espectroscopía fotoelectrónica de rayos X (ESCA), de por lo menos 0, 02 pero menor de 0, 06; (b) se utiliza para proporcionar un flujo de agua filtrada, a una presión de funcionamiento de 0, 3 Mpa, a una temperatura de 25ºC y a un pH de 6, 5, que va desde 0, 8 hasta 4, 0 m 3 /m 2 .día; y (c) es capaz de conseguir un porcentaje de eliminación de ácido húmico de por lo menos 98%.
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公开(公告)号：CA1204667A
公开(公告)日：1986-05-20
申请号：CA438186
申请日：1983-10-03
Applicant: TORAY INDUSTRIES
Inventor： KODAMA MASASHI , KATAYAMA YUTAKA , TANI TORU , TERAMOTO KAZUO , MURAKAMI MUTSUO
IPC: A61K31/715 , A61K35/74 , A61K31/735
Abstract: BLOOD TREATING AGENT The present invention provides (1) a blood-treating material containing a lipopolysaccharide derived from cell walls of Gram-negative bacteria and immobilized by an insoluble carrier containing an amino group and/or a carboxyl group, and (2) a process for producing the blood-treating material in which a condensing agent is reacted with a mixture of the lipopolysaccharide and the insoluble carrier. Lipopolysaccharides have been known to exhibit antitumor effects against malignant tumors. However, they have not been used safely, since their fatal doses are very close to the minimum effective doses in the treatment of such tumors. The present invention makes it possible to reduce the lethal toxicity of the abovementioned lipopolysaccharides and provide a therapy for cancer, because the unique bloodtreating material disclosed herein not only has antitumor effects similar to those of the lipopolysaccharides derived from the cell walls of Gram-negative bacteria but no fatal effects are observed at antitumor effective dosage levels.
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公开(公告)号：DE69920419T2
公开(公告)日：2006-02-23
申请号：DE69920419
申请日：1999-01-14
Applicant: TORAY INDUSTRIES
Inventor： MURAKAMI MUTSUO , TATEISHI YASUSHI , FUSAOKA YOSHINARI
Abstract: The present invention relates to a composite semipermeable membrane which is characterized in that it is a composite semipermeable membrane in which there is formed by polycondensation on top of a microporous support membrane a crosslinked polyamide ultra-thin membrane layer from polyfunctional amine, polyfunctional acid halide and polyfunctional acid anhydride halide, and the flow of water permeate at an operating pressure of 0.3 MPa, a temperature of 25 DEG C and a pH of 6.5 lies in the range from 0.8 to 4.0 m /m .day and, furthermore, the percentage humic acid removal is at least 98%; a method for the production thereof; and a water purification method employing same. With the composite semipermeable membrane obtained by means of the present invention it is possible, in particular, to recover drinking water at a high rate by permitting passage of silica and preventing deposition thereof at the membrane surface while selectively separating/removing the pollutants and trace quantities of harmful materials and their precursors, etc, contained in the raw water in water treatment plants.
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公开(公告)号：DE69920419D1
公开(公告)日：2004-10-28
申请号：DE69920419
申请日：1999-01-14
Applicant: TORAY INDUSTRIES
Inventor： MURAKAMI MUTSUO , TATEISHI YASUSHI , FUSAOKA YOSHINARI
Abstract: The present invention relates to a composite semipermeable membrane which is characterized in that it is a composite semipermeable membrane in which there is formed by polycondensation on top of a microporous support membrane a crosslinked polyamide ultra-thin membrane layer from polyfunctional amine, polyfunctional acid halide and polyfunctional acid anhydride halide, and the flow of water permeate at an operating pressure of 0.3 MPa, a temperature of 25 DEG C and a pH of 6.5 lies in the range from 0.8 to 4.0 m /m .day and, furthermore, the percentage humic acid removal is at least 98%; a method for the production thereof; and a water purification method employing same. With the composite semipermeable membrane obtained by means of the present invention it is possible, in particular, to recover drinking water at a high rate by permitting passage of silica and preventing deposition thereof at the membrane surface while selectively separating/removing the pollutants and trace quantities of harmful materials and their precursors, etc, contained in the raw water in water treatment plants.
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5.发明公开
公开(公告)号：EP1064986A4
公开(公告)日：2001-05-16
申请号：EP99900324
申请日：1999-01-14
Applicant: TORAY INDUSTRIES
Inventor： MURAKAMI MUTSUO , TATEISHI YASUSHI , FUSAOKA YOSHINARI
CPC classification number: B01D69/125 , B01D69/00 , B01D69/02 , B01D71/56 , C02F1/441
Abstract: The present invention relates to a composite semipermeable membrane which is characterized in that it is a composite semipermeable membrane in which there is formed by polycondensation on top of a microporous support membrane a crosslinked polyamide ultra-thin membrane layer from polyfunctional amine, polyfunctional acid halide and polyfunctional acid anhydride halide, and the flow of water permeate at an operating pressure of 0.3 MPa, a temperature of 25 DEG C and a pH of 6.5 lies in the range from 0.8 to 4.0 m /m .day and, furthermore, the percentage humic acid removal is at least 98%; a method for the production thereof; and a water purification method employing same. With the composite semipermeable membrane obtained by means of the present invention it is possible, in particular, to recover drinking water at a high rate by permitting passage of silica and preventing deposition thereof at the membrane surface while selectively separating/removing the pollutants and trace quantities of harmful materials and their precursors, etc, contained in the raw water in water treatment plants.
Abstract translation: 本发明涉及一种复合半透膜的所有这是在为特征做了它是一种复合半透膜，其中有通过缩聚形成在多孔支撑膜的顶端从多官能的交联聚酰胺超薄膜层胺多官能酰卤和 多官能酸酐卤化物和水的流动在渗透在0.3MPa，25℃的温度和6.5的pH处于范围从0.8至4.0米<3> /米<2>·天和的操作压力 ，更进一步，百分比除去腐殖酸是至少98％; 其生产方法; 和水净化方法用人相同。 通过本发明获得的复合半透膜是可能的，特别是，以恢复由允许二氧化硅的通道，并在膜表面上防止沉积而选择性地分离/除去污染物以高速率饮用水和微量 有害物质及其前体等，在水处理厂包含在原水中。
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Patent Agency Ranking
公开(公告)号：JP2004255368A
公开(公告)日：2004-09-16
申请号：JP2003408668
申请日：2003-12-08
Applicant: TORAY INDUSTRIES
Inventor： TANIGUCHI MASAHIDE , MURAKAMI MUTSUO , HANAKAWA MASAYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a composite semipermeable membrane having a high solute removing property and water permeability, the membrane being operable under a low pressure while preventing scaling thereon. SOLUTION: The composite semipermeable membrane having a crosslinked polyamide superthin film layer obtained by the polycondensation reaction of a polyfunctional amine and a polyfunctional acid halide on a fine porous supporting film is characterized in that the polyfunctional amine includes an ortho aromatic diamine having two amino groups at an ortho position (o-) and in that mole% o-aromatic diamine in the total polyfunctional amines in the superthin film is equal to 50-95% or lower according to the 1 H NMR method. COPYRIGHT: (C)2004,JPO&NCIPI
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公开(公告)号：JP2001286741A
公开(公告)日：2001-10-16
申请号：JP2000102092
申请日：2000-04-04
Applicant: TORAY INDUSTRIES
Inventor： TAN KOICHI , INOUE GAKUJI , MURAKAMI MUTSUO
Abstract: PROBLEM TO BE SOLVED: To provide a reverse osmosis composite membrane with outstandingly high water permeability and high desalting rate and a manufacturing method for the membrane, and further, a spiral reverse osmosis composite membrane element using the reverse osmosis composite membrane, a separation device and a water making method. SOLUTION: A separation functional layer containing a polyamide is formed on a porous support membrane and a hydrophilic protection layer is formed by applying a solution containing 0.05-5 wt.% chemical compound with a hydrophilic group and 0.05-3 wt.% crosslinking agent for crosslinking the chemical compound on the separation functional layer in such a way that the solution is 1 nm-10 μm thick. In addition, when the maximum value of an absorption peak within the range of 3,300-3,400 cm-1 measured by the total reflection infrared absorption spectroscopy from the side of the hydrophilic protection layer, is given as RSMAX and the maximum value of an absorption peak within the range of 1,655-1,670 cm-1 measured by the total reflection infrared absorption spectroscopy from the side of the hydrophilic protection layer is given as RAMAX, the value of RSMAX/RAMAX is set within the range of 0.4-5.
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公开(公告)号：JPH09239022A
公开(公告)日：1997-09-16
申请号：JP5166496
申请日：1996-03-08
Applicant: TORAY INDUSTRIES
Inventor： MURAKAMI MUTSUO , MITSUNAGA MASAHIRO , FURUKAWA TAKANORI
Abstract: PROBLEM TO BE SOLVED: To efficiently pack cloth having a body fluid purifying ability into a housing to be packed therewith and to provide a structure which is low in pressure droop and is less in drift by providing the module with the cloth and housing described above and winding the cloth in a roll form around a pipe having a perforated part. SOLUTION: The cloth having the body fluid purifying ability is wound around the pipe which has the perforated part on its circumference, has an aperture at one side in the longitudinal direction and is closed at the other up to the thickness of the diameter of a disk-shaped object 3, to form a roll-like adsorbent 1. The adsorbent is inserted into the housing part and the disk-shaped objects 3, 3' are inserted therein from both ends to set the rolled adsorbent 1 into the housing part; thereafter, a header having an inflow port and outflow port for the body fluid is mounted at the housing, by which the fluid purifying module is formed. If the fluid purifying module is used in extracorporeal circulation, the flow of the body fluid, for example, the body fluid flowing from the header passes the rolled absorbent 1 from the perforated part of the pipe and flows out of the header after the body fluid is purified.
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公开(公告)号：JPH06142181A
公开(公告)日：1994-05-24
申请号：JP29434492
申请日：1992-11-02
Applicant: TORAY INDUSTRIES
Inventor： SHOJI HISANORI , YAMAMOTO YASUHIRO , KODAMA MASATOMO , MITSUNAGA MASAHIRO , MURAKAMI MUTSUO , SUYAMA TOMOKO , NAGAYASU NAOTO
Abstract: PURPOSE:To provide the wound coating material which exhibits an antimicrobial property even without releasing drugs and has a detoxication power to a bacterial toxin by immobilizing polypeptide antibiotics by cavalent bonding to the surfaces of fibers constituting cloth. CONSTITUTION:A polypeptide-based antibiotic is immobilized by covalent bonding to the surfaces of the fibers constituting cloth of a wound coating material. The ratio of the extension rate in the biaxial directions orthogonal to each other of the cloth surface is specified to >=50%. The cloth is formed of a knitted fabric cross knitted of blended fiber consisting of plural blank materials, combined filament yarns and/or plural fibers. As a result, the treatment of the wound is possible without allowing the intrusion of antibiotic into the body through the wound part, and therefore, side effects are prevented. Since an infection prevented, the treatment environment of the wound is improved and further the microbial cell toxin is adsorbed, and therefore an inflammation reaction is suppressed and healing is accelerated.
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10.发明专利
公开(公告)号：JPS63189402A
公开(公告)日：1988-08-05
申请号：JP1849487
申请日：1987-01-30
Applicant: TORAY INDUSTRIES
Inventor： TERAMOTO KAZUO , MURAKAMI MUTSUO
IPC: C08J3/00 , C08F8/30 , C08G85/00 , C08J7/12 , D01D5/36 , D01F8/06 , D06M13/02 , D06M13/248 , D06M13/322 , D06M13/325 , D06M13/328 , D06M13/342 , D06M13/345 , D06M13/368 , D06M13/392 , D06M13/402 , D06M13/432 , D06M101/00 , D06M101/16 , D06M101/18
Abstract: PURPOSE:To obtain the titled polymer having amino group on the side chain and useful as a carrier for immobilizing physiologically active substance, etc., by treating a polymer having functional group containing a specific alpha- haloacetamide group as side chain substituent group or a molded article of said polymer with a hydrophilic tertiary amine and water. CONSTITUTION:A polymer functional group expressed by formula (R1, R2 and R3 are H or lower alkyl; R is conventional substituent group; X is halogen) (e.g. alpha-haloacetamide group) as a side chain substituent group or a molded article of said polymer is added with a hydrophilic tertiary amine (e.g. triethanolamine) and water and heat-treated to hydrolyze the side chain functional group and obtain a polymer having amino group on the side chain or its mold article. A physiologically active substance can be immobilized on said polymer by condensing an amino-protected physiologically active substance such as peptide (e.g. chloroacetylgylcylglycine) in the presence of a condensation agent and removing the protecting group from the product.
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