-
公开(公告)号：WO2022094016A1
公开(公告)日：2022-05-05
申请号：PCT/US2021/056956
申请日：2021-10-28
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： LEVEILLE, Wade P. , MICHIENZI, Joseph D. , MUSACCHIO, Jeffrey , FOGWILL, Michael O.
Abstract: The exemplary embodiments provide chromatography column positioning assemblies that can ensure that the distance between face seals or other sealing surfaces/mechanisms at the respective ends of a liquid chromatography column is a desired distance (i.e., the length of the liquid chromatography column). The exemplary embodiments can adjust the separation between the face seals to accommodate different length liquid chromatography columns. For example, a chromatography column positioning assembly of an exemplary embodiment can set the distance between face seals to accommodate a 25 mm column, a 50 mm column or a 100 mm column.
-
公开(公告)号：WO2021149003A1
公开(公告)日：2021-07-29
申请号：PCT/IB2021/050501
申请日：2021-01-22
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： LEVEILLE, Wade P. , MICHIENZI, Joseph D. , MUSACCHIO, Jeffrey , JONES, Emrys , PRINGLE, Steven Derek , HATTAN, Stephen Joseph , ROMAN, Gregory T.
IPC: H01J49/14 , H01J49/16 , B05B12/32 , B05B5/03 , H01J49/142 , H01J49/167
Abstract: A sprayer assembly for an ion source is disclosed. The sprayer includes a capillary having an outlet, a sheath for the capillary, and an elastic member. The sheath can move relative to the capillary between a first position in which the sheath covers the outlet of the capillary and a second position in which the outlet of the capillary is exposed. When the sheath moves from the first position to or towards the second position, the elastic member provides a restoring force that acts to restore the position of the sheath to or towards the first position.
-
3.发明申请
公开(公告)号：WO2021087212A1
公开(公告)日：2021-05-06
申请号：PCT/US2020/058129
申请日：2020-10-30
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： BASILE, Mark J. , MUSACCHIO, Jeffrey , FOGWILL, Michael O. , BESNER, Sebastien , MICHIENZI, Joseph D. , LEVEILLE, Wade P.
Abstract: Techniques and apparatus for thermally controlled interfaces for separation devices and optical flow cell devices with minimized post-column volumes are described. In one embodiment, for example, a column-optical cell assembly may include an insulating device, a chromatography column arranged within the insulating device, and an optical flow cell in fluid communication with the chromatography column, the chromatography column arranged within a minimum distance of the optical flow cell.
-
公开(公告)号：WO2019126130A1
公开(公告)日：2019-06-27
申请号：PCT/US2018/066171
申请日：2018-12-18
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： JUNG, Moon Chul , TARAFDER, Abhijit , LEVEILLE, Wade P.
CPC classification number: G01N30/14 , B01D15/18 , B01D15/26 , G01N1/34 , G01N30/32 , G01N30/34 , G01N2030/143 , G01N2030/342
Abstract: The invention relates to the purification of liquids. A high surface area-to-volume chemically interactive purification medium is positioned at the outlet of a container that purifies the liquid as it is dispensed/extracted. In one embodiment a purification container (1000) has a box-shaped container body that includes a top surface (882), side surfaces (884) and a bottom surface (886) opposite and parallel to the top surface (882). A set of breathing holes (888) in the top surface enables air to vent into the container so that the flow of the dispensed liquid is not impeded by development of an internal vacuum. A purification module containing purification media (1020) is located at the bottom end of a vertically-oriented tube (890). A mating socket can be used to attach to and seal the top of the tube (890) to a tube/conduit to receive the purified liquid from the container (1000).
-
公开(公告)号：WO2018067304A1
公开(公告)日：2018-04-12
申请号：PCT/US2017/052382
申请日：2017-09-20
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： LEVEILLE, Wade P.
Abstract: A fitting for a fluidic coupling includes a tube assembly that comprises an inner tube (62), an intermediate tube (64) formed of a deformable polymeric material, and an outer tube (66) formed of a metal and disposed over the intermediate tube. The inner tube has an inner tube endface and a first fluid channel. The intermediate tube includes a protruding portion and an intermediate tube endface (70). The outer tube has an outer tube endface (72) and an outer surface. First and second radial crimps (74,76) are formed on the outer surface at first and second distances from the outer tube endface. The inner and outer tube endfaces are co-planar and the intermediate tube endface (70) is separated from the inner and outer tube endfaces by the protruding portion. Rotation of a compression screw (86) drives the tube assembly forward to form a face seal at the intermediate tube endface (70).
Abstract translation: 一种用于流体联接的配件包括管组件，该管组件包括内管（62），由可变形聚合物材料形成的中间管（64）以及由外管（66）形成的外管 金属并设置在中间管上方。 内管具有内管端面和第一流体通道。 中间管包括突出部分和中间管端面（70）。 外管具有外管端面（72）和外表面。 第一和第二径向卷边（74,76）在外表面上以距外管端面第一和第二距离形成。 内管端面和外管端面是共面的，并且中间管端面（70）通过突出部分与内管端面和外管端面分开。 压缩螺钉（86）的旋转向前驱动管组件以在中间管端面（70）形成面密封。
-
Patent Agency Ranking
公开(公告)号：WO2022150442A1
公开(公告)日：2022-07-14
申请号：PCT/US2022/011390
申请日：2022-01-06
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： ANDERSON, Sean Eric , LEVEILLE, Wade P.
Abstract: Described is an active check valve that uses electro-magnetic actuation for operation. The valve includes a plunger assembly having a magnet in a sealed internal volume. The plunger assembly further includes a plunger tip that extends from either a plunger assembly housing or a sealing member. Although the plunger assembly is disposed in the solvent flow, the magnet is not exposed to the solvent. When the valve is actuated, the plunger tip moves the sealing member to open or close the valve. Optionally, an arming force may be applied to the sealing member in advance of opening or closing to reduce the subsequent additional force necessary to move the sealing member during opening or closing, thereby improving the accuracy of the solvent composition in liquid chromatography system applications.
-
公开(公告)号：WO2021222055A1
公开(公告)日：2021-11-04
申请号：PCT/US2021/029055
申请日：2021-04-26
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： LEVEILLE, Wade P. , MICHIENZI, Joseph D. , ANTOCCI, Joseph D. , MUSACCHIO, Jeffrey
IPC: G01N30/60
Abstract: A clamp assembly includes a rail 62 extending along a length and configured to receive a first fluidic assembly, and a carriage 64 movably attachable to the rail 62 such that the carriage moves along the rail, the carriage 64 configured to receive a second fluidic assembly, the carriage including an actuator 65 and a stop mechanism. The stop mechanism is configured to selectively prevent and allow movement of the carriage 64 relative to the rail 62. The stop mechanism is configured to be independently operable from the actuator assembly, and the actuator is configured: to move a chromatography column received by the clamp assembly relative to the rail to create a first fluid tight seal between the chromatography column and the first fluidic assembly, and move the second fluidic assembly relative to the carriage body to create a second fluid tight seal between the second fluidic assembly and the chromatography column.
-
8.发明申请
公开(公告)号：WO2022094031A1
公开(公告)日：2022-05-05
申请号：PCT/US2021/056981
申请日：2021-10-28
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： LEVEILLE, Wade P. , CORMIER, Sylvain G. , FOGWILL, Michael O. , MICHIENZI, Joseph D. , MUSACCHIO, Jeffrey , ANTOCCI, Joseph D.
Abstract: Exemplary embodiments integrate a tee or valve into an outlet end fitting of a liquid chromatography column. The tee or valve is suitable for providing additional fluidic flow paths to ports of the end fitting and eliminates the need for post-column fluidic conduits connecting to tees or valves to insert fluidic inputs or divert flow to outputs. This integration decreases the distance that eluent from the liquid chromatography column has to travel to reach a detector relative to systems that use external tees or valves while providing tee/valve functionality and reducing the fluidic volume post-column. As a result, the exemplary embodiments help decrease sample dispersion.
-
公开(公告)号：WO2018134735A1
公开(公告)日：2018-07-26
申请号：PCT/IB2018/050273
申请日：2018-01-17
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： TARAFDER, Abhijit , JUNG, Moon Chul , BELANGER, Jonathan L. , SONG, Xiangjin , LEVEILLE, Wade P. , BROUSMICHE, Darryl W.
Abstract: Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. A coating is disposed to conform to at least one component of a chromatography system, such as a fitting or a section of tubing. The coating is made of or contains a responsive material that can undergo a detectable change when exposed to a chromatographic fluid or mobile phase. The change of the responsive material can indicate the presence of the fluid or mobile phase, a change in at least one physical property of the coating to prevent passage of the fluid or mobile phase, or a combination thereof.
-
公开(公告)号：WO2018134662A1
公开(公告)日：2018-07-26
申请号：PCT/IB2017/058166
申请日：2017-12-19
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： LEVEILLE, Wade P. , BELANGER, Jonathan L. , JUNG, Moon Chul , TARAFDER, Abhijit , MICHIENZI, Joseph , FADGEN, Keith , WYNDHAM, Kevin , SONG, Xiangjin
IPC: G01N30/32
Abstract: The present disclosure relates to methods and devices for providing pressurized solvent flow in chromatography systems. In one embodiment at least one divert valve is in fluid communication with at least one solvent source (Container); and a pump (LC Pump) is in fluid communication with the at least one divert valve, wherein the at least one divert valve is located in between the at least one solvent source and the pump, and wherein the at least one divert valve is adapted for diverting at least one solvent flow stream to the pump or to an auxiliary flow path.
-
-
-
-
-
-
-
-
-
Search Results
20
records
(took 0.033 seconds)
