公开(公告)号：US20220196639A1

公开(公告)日：2022-06-23

申请号：US17567555

申请日：2022-01-03

Applicant: Labrador Diagnostics LLC

Inventor： Ian Gibbons ,  Michael O'Connell

IPC: G01N33/53 ,  B01L3/00 ,  G01N33/536

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.

公开(公告)号：US11360107B1

公开(公告)日：2022-06-14

申请号：US14631830

申请日：2015-02-25

Applicant: Labrador Diagnostics LLC

Inventor： Daniel Young ,  Samartha Anekal ,  Elizabeth A. Holmes ,  Timothy Smith ,  Chinmay Pangarkar ,  James R. Wasson

IPC: G01N35/00 ,  G01N35/10 ,  C12Q3/00

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US11300564B2

公开(公告)日：2022-04-12

申请号：US15278333

申请日：2016-09-28

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Chinmay Pangarkar ,  Timothy Smith ,  Karan Mohan ,  Daniel Young ,  James Wasson ,  Samartha Anekal

IPC: G01N33/569 ,  B01L3/00 ,  G01N15/10 ,  G02B21/00 ,  G02B21/12 ,  G01N21/05 ,  G02B21/08 ,  G01N33/50 ,  G01N1/30 ,  G01N33/53 ,  G01N33/58 ,  G01N21/64 ,  G02B7/09 ,  G01N21/03 ,  G01N21/17 ,  G02B21/24 ,  G01N33/487 ,  G01N33/49 ,  G01N21/27 ,  G02B21/16 ,  G02B21/36

Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.

公开(公告)号：US11287421B2

公开(公告)日：2022-03-29

申请号：US15951641

申请日：2018-04-12

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Shaunak Roy ,  Ian Gibbons ,  Shize Daniel Qi ,  Edmond Ku ,  Chris Todd ,  Melissa Takahashi ,  Bruce Johnson ,  Jeff Fenton ,  Keith Moravick ,  Uwe Springborn ,  Anthony Delacruz

IPC: B01L99/00 ,  G01N33/53 ,  A61B5/15 ,  A61B5/1486 ,  A61B5/00 ,  G01N33/536 ,  G01N33/573 ,  A61B5/151 ,  A61B5/157

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US11275094B2

公开(公告)日：2022-03-15

申请号：US16554969

申请日：2019-08-29

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Adrit Lath

IPC: G01N35/00 ,  B01L3/00 ,  G01N35/02 ,  G01N35/10 ,  G01N35/04

Abstract: Systems and methods are provided for processing a biological sample. In one embodiment, the method comprises receiving a sample vessel containing the sample; retrieving information from an information storage unit associated with the sample; using said information for selecting at least one cartridge front at least two or more different cartridges, each configured for use with a sample processing device; loading at least one or more reagents onto the cartridge, wherein the one or more reagents to be added are selected based at least in part on the information or instructions derived from the information; and placing the sample vessel in the cartridge.

公开(公告)号：US11262308B2

公开(公告)日：2022-03-01

申请号：US17078936

申请日：2020-10-23

Applicant: Labrador Diagnostics LLC

Inventor： Chinmay Pangarkar ,  Karan Mohan

IPC: G01N21/64 ,  G01N21/47 ,  G01N15/14

Abstract: Methods and devices for cytometric analysis are provided. A cytometry apparatus is provided which may be used with a stationary sample cuvette for analysis of a stationary sample or with a flow sample cuvette for analysis of a flowing sample. The methods and devices provided herein may be used to perform cytometric analysis of samples under a wide range of experimental and environmental conditions.

公开(公告)号：US11257215B2

公开(公告)日：2022-02-22

申请号：US16778244

申请日：2020-01-31

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes

IPC: G06T7/00 ,  G06F15/16

Abstract: Systems and methods are provided for collecting, preparing, and/or analyzing a biological sample. A sample collection site may be utilized with one or more sample processing device. The sample processing device may be configured to accept a sample from a subject. The sample processing device may perform one or more sample preparation step and/or chemical reaction involving the sample. Data related to the sample may be sent from the device to a laboratory. The laboratory may be a certified laboratory that may generate a report that is transmitted to a health care professional. The health care professional may rely on the report for diagnosing, treating, and/or preventing a disease in the subject.

公开(公告)号：US11254960B2

公开(公告)日：2022-02-22

申请号：US14848220

申请日：2015-09-08

Applicant: Labrador Diagnostics LLC

Inventor： Kamila Belhocine ,  Pranav Patel ,  Josephine Lee ,  Aaron Richardson ,  Scott Tabakman

IPC: C12P19/34 ,  C12Q1/6827 ,  C12Q1/6844

Abstract: Methods and compositions for the amplification of nucleic acids are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such as nucleic acid polymerases, ligases, and primers.

公开(公告)号：US20210341500A1

公开(公告)日：2021-11-04

申请号：US17229518

申请日：2021-04-13

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Joy Roy ,  Peter Kardassakis ,  Sunny Balwani

IPC: G01N35/00 ,  B01L3/02 ,  G01N35/10 ,  G01N30/88

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US11112418B1

公开(公告)日：2021-09-07

申请号：US15664138

申请日：2017-07-31

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Daniel Young ,  Samartha Anekal ,  Chinmay Pangarkar

IPC: G01N35/00 ,  G01N15/14 ,  G01N21/01 ,  B01L3/00 ,  G01N15/00

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.