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    AUTOMATIC ANALYZER
    101.
    发明申请
    AUTOMATIC ANALYZER 有权
    自动分析仪

    公开(公告)号：US20130301048A1

    公开(公告)日：2013-11-14

    申请号：US13979668

    申请日：2012-01-10

    Applicant: Akihisa Makino ,  Sakuichiro Adachi

    Inventor： Akihisa Makino ,  Sakuichiro Adachi

    IPC: G01N21/49

    CPC classification number: G01N21/49 ,  G01N21/51 ,  G01N35/00693 ,  G01N2201/0415 ,  G01N2201/1211

    Abstract: The scattered light from the measurement target substance passes through a light receiving window, and is received by a detector for +θ scattered light and a detector for −θ scattered light which are arranged symmetrically to each other across an optical axis at an equal angle or an equal interval in a vertical direction. A light source is fixed by a light-source holder (that is a base member on which the light source is arranged), and the detectors are arranged on and fixed to a detector holder (that is a base member on which the detectors are arranged). In this manner, drift of the light quantity data caused by the thermal deformation of the optical system can be corrected by comparing values of the light quantity data of the detectors.

    Abstract translation: 来自测量对象物质的散射光通过光接收窗，并且由用于+θ散射光的检测器和用于散射光的检测器接收，所述检测器以相等的角度跨越光轴彼此对称布置，或 在垂直方向上相等的间隔。 光源由光源保持器（即配置有光源的基底部件）固定，检测器被配置在检测器支架（作为检测器布置在其上的基底部件）上并固定 ）。 以这种方式，可以通过比较检测器的光量数据的值来校正由光学系统的热变形引起的光量数据的漂移。

    TEST TAPE DEVICE
    102.
    发明申请
    TEST TAPE DEVICE 有权
    测试带设备

    公开(公告)号：US20130267815A1

    公开(公告)日：2013-10-10

    申请号：US13910261

    申请日：2013-06-05

    Applicant: Roche Diagnostics Operations, Inc.

    Inventor： Hao-Chih Lin ,  Wen Tsung Wang

    IPC: A61B5/145

    CPC classification number: A61B5/14532 ,  A61B5/150022 ,  A61B5/150259 ,  A61B5/150267 ,  A61B5/150358 ,  A61B5/15113 ,  A61B5/15115 ,  A61B5/15186 ,  A61B5/157 ,  A61B2562/0295 ,  G01N33/48764 ,  G01N35/00009 ,  G01N2021/478 ,  G01N2035/00019 ,  G01N2201/0415 ,  G01N2201/0621 ,  Y10T436/144444

    Abstract: A test tape device is disclosed herein for use with a replaceable analytical tape cassette, where the device includes a housing having a cassette compartment covered by a cassette door and a housing opening for sample application, a protective cover that can be moved between a closed position covering the housing opening and a release position allowing access to the housing opening and a door lock for retaining the cassette door in the closed position, wherein the protective cover is coupled with the door lock via an interlocking mechanism, such that the door lock can only be unlocked in the release position of the cover.

    Abstract translation: 本文公开了一种与可替换的分析带盒一起使用的测试带装置，其中该装置包括具有由盒门覆盖的盒室和用于样品施加的壳体开口的壳体，保护盖可以在闭合位置 覆盖壳体开口和允许进入壳体开口的释放位置和用于将盒门保持在关闭位置的门锁，其中保护盖通过联锁机构与门锁联接，使得门锁只能 在盖的释放位置被解锁。

    Surface plasmon resonance measuring chip and method of manufacture thereof
    104.
    发明授权
    Surface plasmon resonance measuring chip and method of manufacture thereof 有权
    表面等离子共振测量芯片及其制造方法

    公开(公告)号：US08268613B2

    公开(公告)日：2012-09-18

    申请号：US12761221

    申请日：2010-04-15

    Applicant: Masayuki Naya ,  Takashi Kubo ,  Takashi Ito ,  Yoshimitsu Nomura

    Inventor： Masayuki Naya ,  Takashi Kubo ,  Takashi Ito ,  Yoshimitsu Nomura

    IPC: C12M1/34

    CPC classification number: G01N21/553 ,  B29C45/0025 ,  B29C2045/0027 ,  G01N2201/0415

    Abstract: A surface plasmon resonance measuring apparatus is provided with a dielectric block, a metal film formed on a surface of the dielectric block, a light source for emitting a light beam, an optical system for making the light beam enter the dielectric block at various angles of incidence so that a condition for total internal reflection is satisfied at an interface between the dielectric block and the thin film layer, and a photodetector for detecting the intensity of the light beam satisfying total internal reflection at the interface. In the measurement chip to be utilized in the surface plasmon resonance measuring apparatus, the dielectric block is formed from a synthetic resin in which, when said light beam is p-polarized outside said dielectric block and then strikes the interface, the intensity of a s-polarized component at the interface is 50% or less of the intensity of the light beam at the interface.

    Abstract translation: 表面等离子体共振测定装置具备介质块，形成在介质块的表面上的金属膜，用于发射光束的光源，使光束以各种角度进入介质块的光学系统 入射，使得在介电块和薄膜层之间的界面处满足全内反射条件，以及用于检测在界面处满足全内反射的光束的强度的光电检测器。 在表面等离子体共振测定装置中使用的测量芯片中，介电块由合成树脂形成，其中当所述光束在所述介质块外部p偏振，然后撞击界面时，s的强度 界面处的极化分量为界面光束强度的50％以下。

    AUTOMATIC ANALYZER
    105.
    发明申请
    AUTOMATIC ANALYZER 有权
    自动分析仪

    公开(公告)号：US20120148450A1

    公开(公告)日：2012-06-14

    申请号：US13401047

    申请日：2012-02-21

    Applicant: Kanako IWAMURA ,  Shoichi Kanayama

    Inventor： Kanako IWAMURA ,  Shoichi Kanayama

    IPC: G01N21/59

    CPC classification number: G01N21/253 ,  G01N35/025 ,  G01N35/04 ,  G01N2035/0455 ,  G01N2201/0415 ,  G01N2201/124 ,  G01N2201/1245 ,  G01N2201/127

    Abstract: According to one embodiment, an automatic analyzer comprises a light source, a spectroscope, a photo detection unit, a storage unit, a selection unit, and a calculation unit. The storage unit stores photo detector identifiers related to photo detectors and wavelength band identifiers in association with each other. The selection unit selects a specific photo detector from photo detectors. The specific photo detector corresponds to a specific photo detector identifier associated with a wavelength band identifier of a wavelength band according to a measurement item of a sample. The calculation unit calculates an absorbance related to the measurement item based on a signal from the selected specific photo detector.

    Abstract translation: 根据一个实施例，自动分析仪包括光源，分光镜，光检测单元，存储单元，选择单元和计算单元。 存储单元相关联地存储与光检测器和波长带标识符相关的光检测器标识符。 选择单元从光电检测器中选择特定的光电检测器。 特定的光检测器对应于根据样品的测量项目与波长带的波长带标识符相关联的特定光检测器标识符。 计算单元基于来自所选择的特定光检测器的信号计算与测量项目相关的吸光度。

    OPTICAL MEASUREMENT ARRANGEMENT
    108.
    发明申请
    OPTICAL MEASUREMENT ARRANGEMENT 有权
    光学测量装置

    公开(公告)号：US20100200728A1

    公开(公告)日：2010-08-12

    申请号：US12697618

    申请日：2010-02-01

    Applicant: Gal Ingber

    Inventor： Gal Ingber

    IPC: G01J1/32

    CPC classification number: G01J1/32 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/031 ,  G01N21/253 ,  G01N2201/0415 ,  G01N2201/0469 ,  G01N2201/0692

    Abstract: A method and device for enhancing the power correction of optical measurements in an optical measurement arrangement, the steps including: providing a light source for producing a light beam; splitting the light beam into two beams; directing a first split light beam through an interrogation area and into an optics separation device; directing the light beams from the optics separation device and a second split light beam representing the intensity of the illumination of the main light beam of the light source into cells of a detector array; measuring and assessing the information obtained in the cells; and using this information to calculate the corrected value for the cells receiving the light beams from the optics separation device in order to adjust the power for the intensity of the light beam of the light source and/or to correct the intensity of the light beams from the interrogation area.

    Abstract translation: 一种用于增强光学测量装置中的光学测量的功率校正的方法和装置，所述步骤包括：提供用于产生光束的光源; 将光束分成两束; 将第一分裂光束引导通过询问区并进入光学分离装置; 引导来自光学分离装置的光束和将光源的主光束的照明强度表示为检测器阵列的单元的第二分裂光束; 测量和评估细胞中获得的信息; 并且使用该信息来计算接收来自光学分离装置的光束的单元的校正值，以便调整光源的光束强度的功率和/或校正来自光源的光束的强度 询问区。

    SURFACE PLASMON RESONANCE MEASURING CHIP AND METHOD OF MANUFACTURE THEREOF
    109.
    发明申请
    SURFACE PLASMON RESONANCE MEASURING CHIP AND METHOD OF MANUFACTURE THEREOF 有权
    表面质子共振测量芯片及其制造方法

    公开(公告)号：US20100195107A1

    公开(公告)日：2010-08-05

    申请号：US12761221

    申请日：2010-04-15

    Applicant: Masayuki Naya ,  Takashi Kubo ,  Takashi Ito ,  Yoshimitsu Nomura

    Inventor： Masayuki Naya ,  Takashi Kubo ,  Takashi Ito ,  Yoshimitsu Nomura

    IPC: G01N21/55

    CPC classification number: G01N21/553 ,  B29C45/0025 ,  B29C2045/0027 ,  G01N2201/0415

    Abstract: A surface plasmon resonance measuring apparatus is provided with a dielectric block, a metal film formed on a surface of the dielectric block, a light source for emitting a light beam, an optical system for making the light beam enter the dielectric block at various angles of incidence so that a condition for total internal reflection is satisfied at an interface between the dielectric block and the thin film layer, and a photodetector for detecting the intensity of the light beam satisfying total internal reflection at the interface. In the measurement chip to be utilized in the surface plasmon resonance measuring apparatus, the dielectric block is formed from a synthetic resin in which, when said light beam is p-polarized outside said dielectric block and then strikes the interface, the intensity of a s-polarized component at the interface is 50% or less of the intensity of the light beam at the interface.

    Abstract translation: 表面等离子体共振测定装置具备介质块，形成在介质块的表面上的金属膜，用于发射光束的光源，使光束以各种角度进入介质块的光学系统 入射，使得在介电块和薄膜层之间的界面处满足全内反射条件，以及用于检测在界面处满足全内反射的光束的强度的光电检测器。 在表面等离子体共振测定装置中使用的测量芯片中，介电块由合成树脂形成，其中当所述光束在所述介质块外部p偏振，然后撞击界面时，s的强度 界面处的极化分量为界面光束强度的50％以下。

    ROTARY ARRAY MODULE FOR MULTIPLEXING SPOT-BASED OPTICAL READOUTS
    110.
    发明申请
    ROTARY ARRAY MODULE FOR MULTIPLEXING SPOT-BASED OPTICAL READOUTS 审中-公开
    用于基于点阵光学准备的旋转阵列模块

    公开(公告)号：US20100075863A1

    公开(公告)日：2010-03-25

    申请号：US12237954

    申请日：2008-09-25

    Applicant: Matthew J. LESHO ,  Christopher G. COONEY

    Inventor： Matthew J. LESHO ,  Christopher G. COONEY

    IPC: C40B30/04 ,  C40B60/12

    CPC classification number: G01N21/6452 ,  B01J2219/00536 ,  B01J2219/00576 ,  B01J2219/00596 ,  B01J2219/00659 ,  G01N2201/0415

    Abstract: An apparatus for multiplexing detection of one or more of a plurality of target molecules in a liquid sample includes a sample chamber adapted to receive a liquid sample containing one or more target molecules and a rotary array disposed in the sample chamber. The rotary array includes a plurality of spots, with each spot including at least one probe molecule selected to bind to a particular region of a target molecule. The apparatus also includes an optical detector capable of determining if a target molecule has bound to one of the probe molecules as the array rotates within the sample chamber.

    Abstract translation: 用于复用液体样品中多个目标分子中的一种或多种的检测装置包括：适于接收含有一种或多种靶分子的液体样品和设置在样品室中的旋转阵列的样品室。 旋转阵列包括多个斑点，其中每个斑点包括选择以结合靶分子的特定区域的至少一个探针分子。 该装置还包括光学检测器，其能够在阵列在样品室内旋转时确定靶分子是否与探针分子中的一个结合。

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