公开(公告)号：US11099068B2

公开(公告)日：2021-08-24

申请号：US15448701

申请日：2017-03-03

Applicant: FILMETRICS, INC.

Inventor： Scott A. Chalmers ,  Randall S. Geels ,  Matthew F. Ross

IPC: G01J3/10 ,  G01N21/45 ,  G01J3/26 ,  G01N21/25 ,  G01B11/06 ,  G01N21/84 ,  G01J3/12 ,  G01J3/28

Abstract: A system comprising a light source, and a retention device configured to receive and retain a sample for measurement. The system includes a detector. An optical path couples light between the light source, the sample when present, and the detector. An optical objective is configured to couple light from the light source to the sample when present, and couple reflected light to the detector. A controller is configured to automatically control focus and/or beam path of the light directed by the optical objective to the sample when present. The system includes a spatially variable filter (SVF) positioned in the optical path. The SVF is configured to have spectral properties that vary as a function of illuminated position on the SVF.

公开(公告)号：US11092488B2

公开(公告)日：2021-08-17

申请号：US16485870

申请日：2018-02-13

Applicant: UNIVERSITY OF THE WEST OF SCOTLAND

Inventor： Ewan Waddell ,  Desmond Gibson

IPC: G01J3/10 ,  G01J3/02 ,  G01J3/12 ,  G01J3/42 ,  G01N21/3504 ,  G01N21/3577

Abstract: An optical sensor for multispectral analysis of a fluid sample comprises at least one light source, at least one interference filter, and a plurality of light detectors arranged such that light emitted by the at least one light source is incident on the at least one interference filter. There is a spatial variation in the intensity of light incident on the said at least one interference filter.

公开(公告)号：US20210223103A1

公开(公告)日：2021-07-22

申请号：US16861613

申请日：2020-04-29

Applicant: National Taiwan University

Inventor： Ching-Fuh Lin ,  Ta-Jung Lin

IPC: G01J3/28 ,  G01J3/10 ,  G01J3/02 ,  G01J3/12

Abstract: The present invention provides a spectral imaging device characterized in that N images are captured with ambient light, and spectra can be obtained from the captured N images for spectral analysis. In particular, a filter device is employed to divide a spectral range of the ambient light into N spectral bands, and each capture corresponds to one spectral band.

公开(公告)号：US20210196155A1

公开(公告)日：2021-07-01

申请号：US17203087

申请日：2021-03-16

Applicant: Rijul GUPTA

Inventor： Rijul GUPTA

IPC: A61B5/1455 ,  A61B5/145 ,  G01J3/00 ,  A61B5/00 ,  G01N21/31 ,  G01N21/47 ,  G01J3/28 ,  G01N21/49 ,  G01J3/02 ,  G01J3/10 ,  G01J3/427 ,  G01J3/457

Abstract: A multi-channel measurement device for measuring properties of human tissue, may comprise a microcontroller and first and second source/sensor complexes. The first source/sensor complex may include a first housing having a first measurement portion, a first light sensor coupled to the microcontroller and exposed to the first measurement portion, and a first plurality of light sources coupled to the microcontroller and exposed to the first measurement portion. The second source/sensor complex may include a second housing having a second measurement portion, a second light sensor coupled to the microcontroller and exposed to the second measurement portion, and a second plurality of light sources coupled to the microcontroller and exposed to the second measurement portion. The first and second source/sensor complexes are coupled to each other such that the first measurement portion is opposite the second measurement portion and human tissue may be placed between the the first and second measurement portions. The microprocessor is configured with instructions stored in non-volatile memory to individually activate each of the light sources of the first and second pluralities of light sources and to record light intensity detected by the first and second light sources while an individual light source is activated. Each combination of an individually activated light source and one of the first and second light sensors provides a distinct measurement channel for measuring the absorption spectra of human blood and tissue.

公开(公告)号：US11044795B2

公开(公告)日：2021-06-22

申请号：US16511773

申请日：2019-07-15

Applicant: OPPLE LIGHTING CO., LTD.

Inventor： Aiqin Huang ,  Mantang Hong ,  Song Yin ,  Jianguo Li ,  Shitao Deng

IPC: H05B47/105 ,  G01J3/46 ,  G01J3/50 ,  G01J3/02 ,  G01J3/10 ,  G02B7/02 ,  G02B13/00 ,  G02B9/12 ,  H05B47/11

Abstract: A color picking device and a color picking remote controller are provided. The color picking device is configured to acquire a color of a target object, which includes: a substrate; a light emitting module configured to emit white light toward the target object, where the light emitting module that includes a light source and a light distribution element; and a color receiving module configured to receive light reflected by the target object and having the color of the target object after the target object is illuminated by the white light, where the color receiving module includes a first housing, a lens assembly disposed in the first housing, and the sensing element, where the lens assembly includes a first convex lens, an aperture, a concave lens and a second convex lens that are coaxially arranged from top to bottom along a top of the first housing.

公开(公告)号：US11041759B2

公开(公告)日：2021-06-22

申请号：US16456188

申请日：2019-06-28

Applicant: Massachusetts Institute of Technology

Inventor： Juejun Hu ,  Derek Kita ,  Jerome Michon

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/10 ,  G01N21/65

Abstract: A method of performing Raman spectroscopy can include guiding a Raman pump beam with an optical fiber, where the Raman pump beam inducing fluorescence in the optical fiber. The beam and the fluorescence are coupled to a photonic integrated circuit (PIC) via the fiber. The beam is used to excite a sample in optical communication with the PIC via evanescent coupling and induces Raman scattering in the sample. The Raman scattering is collected via the PIC, and the Raman pump beam as well as the fluorescence is filtered out from the Raman scattering via the PIC.

公开(公告)号：US11022620B2

公开(公告)日：2021-06-01

申请号：US16349075

申请日：2017-11-13

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Stefan Kluckner ,  Shanhui Sun ,  Yao-Jen Chang ,  Terrence Chen ,  Benjamin S. Pollack

IPC: G01N35/00 ,  G06T7/11 ,  B01L9/00 ,  G01N21/27 ,  G06T7/00 ,  G01J3/10 ,  G01N21/25 ,  G01J3/28 ,  G06T5/50 ,  G01B11/00 ,  G01B11/06

Abstract: A method of characterizing a specimen for HILN (H, I, and/or L, or N). The method includes capturing images of the specimen at multiple different viewpoints, processing the images to provide segmentation information for each viewpoint, generating a semantic map from the segmentation information, selecting a synthetic viewpoint, identifying front view semantic data and back view semantic data for the synthetic viewpoint, and determining HILN of the serum or plasma portion based on the front view semantic data with an HILN classifier, while taking into account back view semantic data. Testing apparatus and quality check modules adapted to carry out the method are described, as are other aspects.

公开(公告)号：US11022492B2

公开(公告)日：2021-06-01

申请号：US16625682

申请日：2018-07-06

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomofumi Suzuki ,  Kyosuke Kotani ,  Tatsuya Sugimoto ,  Yutaka Kuramoto ,  Katsumi Shibayama ,  Noburo Hosokawa

IPC: G01J3/45 ,  G01J3/14 ,  B81B3/00 ,  G01J3/02 ,  G01J3/10 ,  G01B9/02 ,  G02B7/182 ,  G02B26/08

Abstract: An optical module 1A includes a mirror unit 2 including a movable mirror 22 and a fixed mirror 16, a beam splitter unit 3, a light incident unit 4, a first light detector 6, a second light source 7, a second light detector 8, a holding unit 130, a first mirror 51, a second mirror 52, and a third mirror 53. The holding unit 130 holds the first light detector 6, the second light detector 8, and the second light source 7 so as to face that same side, and to be aligned in this order. A length of an optical path between the unit 3 and the detector 6 is shorter than a length of an optical path between the unit 3 and the detector 8, and a length of an optical path between the unit 3 and the source 7.

公开(公告)号：US11015975B2

公开(公告)日：2021-05-25

申请号：US16613614

申请日：2018-05-15

Applicant: The Trustees of Princeton University

Inventor： Lukasz Sterczewski ,  Jonas Westberg ,  Gerard Wysocki

IPC: G01J3/10 ,  G01J3/427

Abstract: Disclosed herein is an all-digital phase and timing correction procedure for coherent averaging in dual-comb and multiheterodyne spectroscopy—applicable to any dual-comb spectroscopy setup. It can account for large frequency/phase instabilities of the used sources, yielding a significant reduction of the noise pedestal and an increase in signal-to-noise ratio (SNR) of the radio frequency (RF) beat notes. This technique is computationally efficient and can be conveniently implemented either as a post-processing algorithm or in a real-time data acquisition and processing platform without the necessity of adding any additional optical elements to the dual-comb spectroscopy system. By implementing this technique, the performance of any comb- or comb-like-source-based DCS system with a sufficient degree of mutual coherence between the optical modes can be improved in terms of SNR and number of spectroscopically-usable RF beat notes. The described technique is compatible with a DC-centered RF spectrum, where the negative frequencies are folded to the positive domain to double the number of beat notes within the detector bandwidth. The technique enables coherent averaging over extended time-scales even for free-running combs, thus increasing the sensitivity of absorption and dispersion DCS measurements.

公开(公告)号：US20210140817A1

公开(公告)日：2021-05-13

申请号：US17093211

申请日：2020-11-09

Applicant: California Institute of Technology

Inventor： Axel Scherer ,  Taeyoon Jeon ,  Jieun Myung

IPC: G01J3/12 ,  G01J3/10

Abstract: An infrared spectrometer for operation in the mid-infrared spectral range is disclosed, where the spectrometer includes a Bragg-mirror-based spectral filter that is operative for providing an output optical signal whose spectral content is spatially dispersed along a first direction, where the Bragg mirrors include low-refractive-index layers comprising a polymer material that is transmissive across the mid-infrared spectral range and is characterized by less than ten absorption peaks with the operating spectral range of the spectrometer.