中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

261 records (took 0.026 seconds)

    DEVICE AND METHOD FOR DETECTING AN ANALYTE
    181.
    发明申请
    DEVICE AND METHOD FOR DETECTING AN ANALYTE 有权
    用于检测分析仪的装置和方法

    公开(公告)号：US20160123968A1

    公开(公告)日：2016-05-05

    申请号：US14894452

    申请日：2014-05-30

    Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION

    Inventor： Takuya IIDA ,  Shiho TOKONAMI

    IPC: G01N33/543 ,  G01N21/21 ,  G01N21/65 ,  G01N33/553 ,  G01N33/53

    CPC classification number: G01N33/54346 ,  C12Q1/6834 ,  C12Q2563/155 ,  C12Q2565/628 ,  G01N21/21 ,  G01N21/554 ,  G01N21/658 ,  G01N33/5308 ,  G01N33/553 ,  G01N2201/061 ,  G01N2201/0683

    Abstract: A detection device detects an analyte that may be contained in a specimen. The detection device includes a plurality of gold nanoparticles, an optical trapping light source, an illumination light source, an objective lens, an image pick-up device, and a computation unit. The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device receives light from the liquid. The computation unit detects an analyte based on a signal received from the image pick-up device.

    Abstract translation: 检测装置检测可能包含在样本中的分析物。 检测装置包括多个金纳米颗粒，光学捕获光源，照明光源，物镜，图像拾取装置和计算单元。 多个金纳米颗粒各自用探针DNA修饰，允许分析物特异性地粘附于其上。 光捕获光源发射用于将多个金纳米颗粒组装在一起的偏振光。 物镜聚焦并将偏振光引入含有样品和多个金纳米颗粒的液体中。 摄像装置接收来自液体的光。 计算单元基于从图像拾取装置接收的信号检测分析物。

    Apparatus and methods for concentration determination using polarized light
    182.
    发明授权
    Apparatus and methods for concentration determination using polarized light 有权

    公开(公告)号：US09310314B2

    公开(公告)日：2016-04-12

    申请号：US14617303

    申请日：2015-02-09

    Applicant: DEKA Products Limited Partnership

    Inventor： Jacob W. Scarpaci ,  Jason M. Sachs ,  Simon C. Helmore

    IPC: G01J4/00 ,  G01N21/90 ,  G01J4/04 ,  G01N21/21

    CPC classification number: G01N21/21 ,  A61M1/14 ,  G01J4/04 ,  G01N21/90 ,  G01N2201/0612 ,  G01N2201/0683

    Abstract: Methods and apparatus for concentration determination using polarized light. The apparatus includes a first polarized light source having a first light source polarization axis and a second polarized light source having a second light source polarization axis generally perpendicular to the first light source polarization axis. Also, a first polarized light receiver having a first polarized light receiver polarization axis and configured to measure an intensity of light transmitted from the first light receiver polarizer and a second polarized light receiver having a second polarized light receiver polarization axis substantially perpendicular to the first light receiver polarization axis and configured to measure an intensity of light transmitted from the second light receiver polarizer, wherein the first and second light receiver polarization axes are generally +/−45 degrees relative to the first and second light source polarization axes.

    Temperature-stable incoherent light source
    184.
    发明授权
    Temperature-stable incoherent light source 有权
    温度稳定的非相干光源

    公开(公告)号：US08902425B2

    公开(公告)日：2014-12-02

    申请号：US13857273

    申请日：2013-04-05

    Applicant: Dubravko Ivan Babic

    Inventor： Dubravko Ivan Babic

    IPC: G01B9/02 ,  G01N21/53

    CPC classification number: G01B9/02055 ,  G01N21/532 ,  G01N2201/0683 ,  G01N2201/1211

    Abstract: Embodiments generally relate to a light source and methods for minimizing temperature sensitivity of a light source light source. In one embodiment a light source includes a light-emitting diode, a light beam having an optical axis, a photodetector and a polarizer. The diode is operatively configured to emit the light beam. The beam splitter, positioned to intercept the light beam, includes a first optical surface operatively configured to reflect a first portion of the light beam and to transmit a second portion of the light beam therethrough. The photodetector is positioned to capture the first portion of the light beam after reflection by the beam splitter and operatively configured to generate photocurrent proportional to an intensity of that captured first portion. The polarizer is positioned between the diode and the beam splitter, and is operatively configured to polarize the light beam along a polarization direction perpendicular to its optical axis.

    Abstract translation: 实施例通常涉及光源和用于使光源光源的温度敏感度最小化的方法。 在一个实施例中，光源包括发光二极管，具有光轴的光束，光电检测器和偏振器。 二极管可操作地配置成发射光束。 定位成拦截光束的分束器包括可操作地配置为反射光束的第一部分并透射光束的第二部分的第一光学表面。 光电检测器被定位成在分束器反射之后捕获光束的第一部分，并且可操作地配置成产生与所捕获的第一部分的强度成比例的光电流。 偏振器位于二极管和分束器之间，并且可操作地构造成沿着垂直于其光轴的偏振方向使光束偏振。

    SIMPLE SUGAR CONCENTRATION SENSOR AND METHOD
    185.
    发明申请
    SIMPLE SUGAR CONCENTRATION SENSOR AND METHOD 有权

    公开(公告)号：US20140104596A1

    公开(公告)日：2014-04-17

    申请号：US13950054

    申请日：2013-07-24

    Applicant: Valentin Korman

    Inventor： Valentin Korman

    IPC: G01N21/21

    CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/6815 ,  A61B5/7225 ,  A61B2560/0443 ,  A61B2562/0238 ,  G01N21/21 ,  G01N2201/062 ,  G01N2201/0683

    Abstract: A glucose sensor comprising an optical energy source having an emitter with an emission pattern; a first polarizer intersecting the emission pattern; a second polarizer spaced a distance from the first polarizer and intersecting the emission pattern, the second polarizer rotated relative to the first polarizer by a first rotational amount Θ; a first optical detector intersecting the emission pattern; a second optical detector positioned proximal to the second polarizer, the first polarizer and the second polarizer being positioned between the optical energy source and the second optical detector, the second optical detector intersecting the emission pattern; a compensating circuit coupled to the second optical detector; and a subtractor circuit coupled to the compensating circuit and the first optical detector.

    CHEMICAL CHARACTERIZATION OF SURFACE FEATURES
    186.
    发明申请
    CHEMICAL CHARACTERIZATION OF SURFACE FEATURES 有权
    表面特征的化学特征

    公开(公告)号：US20140098368A1

    公开(公告)日：2014-04-10

    申请号：US14032192

    申请日：2013-09-19

    Applicant: Seagate Technology LLC

    Inventor： Joachim Walter Ahner ,  Samuel Kah Hean Wong ,  Maissarath Nassirou ,  Henry Luis Lott ,  David M. Tung ,  Florin Zavaliche ,  Stephen Keith McLaurin

    IPC: G01N21/47

    CPC classification number: G01N21/4738 ,  G01N21/95 ,  G01N2021/4764 ,  G01N2021/4792 ,  G01N2201/0635 ,  G01N2201/0683

    Abstract: Provided herein is an apparatus, including an optical characterization device; a photon detector array configured to sequentially receive a first set of photons scattered from surface features of an article and a second set of photons scattered from surface features of the article and subsequently processed by the optical characterization device; and a chemical characterization means for chemically characterizing the surface features of the article, wherein the chemical characterization means is configured for processing the first set of photons received by the photon detector array and the second set of photons received by the photon detector array.

    Abstract translation: 本文提供的装置包括光学表征装置; 光子检测器阵列，其被配置为顺序地接收从制品的表面特征散射并随后由所述光学表征装置处理的物品的表面特征散射的第一组光子和第二组光子; 以及用于化学表征所述制品的表面特征的化学表征装置，其中所述化学表征装置被配置用于处理由所述光子检测器阵列接收的第一组光子和由所述光子检测器阵列接收的所述第二组光子。

    Apparatus and methods for concentration determination using polarized light
    188.
    发明授权
    Apparatus and methods for concentration determination using polarized light 有权
    使用偏振光进行浓缩测定的装置和方法

    公开(公告)号：US08432547B2

    公开(公告)日：2013-04-30

    申请号：US12829616

    申请日：2010-07-02

    Applicant: Jacob W. Scarpaci ,  Jason M. Sachs ,  Simon C. Helmore

    Inventor： Jacob W. Scarpaci ,  Jason M. Sachs ,  Simon C. Helmore

    IPC: G01J4/00

    CPC classification number: G01N21/21 ,  A61M1/14 ,  G01J4/04 ,  G01N21/90 ,  G01N2201/0612 ,  G01N2201/0683

    Abstract: Methods and apparatus for concentration determination using polarized light. The apparatus includes a first polarized light source having a first light source polarization axis and a second polarized light source having a second light source polarization axis generally perpendicular to the first light source polarization axis. Also, a first polarized light receiver having a first polarized light receiver polarization axis and configured to measure an intensity of light transmitted from the first light receiver polarizer and a second polarized light receiver having a second polarized light receiver polarization axis substantially perpendicular to the first light receiver polarization axis and configured to measure an intensity of light transmitted from the second light receiver polarizer, wherein the first and second light receiver polarization axes are generally +/−45 degrees relative to the first and second light source polarization axes.

    Abstract translation: 使用偏振光进行浓度测定的方法和装置。 该装置包括具有第一光源偏振轴的第一偏振光源和具有大致垂直于第一光源偏振轴的第二光源偏振轴的第二偏振光源。 此外，具有第一偏振光接收偏振轴并被配置为测量从第一光接收偏振器透射的光的强度的第一偏振光接收器和具有基本上垂直于第一光的第二偏振光接收偏振轴的第二偏振光接收器 接收器偏振轴并且被配置为测量从第二光接收偏振器透射的光的强度，其中第一和第二光接收偏振轴相对于第一和第二光源偏振轴通常为+/- 45度。

    Apparatus for the non-invasive measurement of tissue function and metabolism by determination of steady-state fluorescence anisotropy
    189.
    发明授权
    Apparatus for the non-invasive measurement of tissue function and metabolism by determination of steady-state fluorescence anisotropy 有权
    用于通过测定稳态荧光各向异性来非组织测量组织功能和代谢的装置

    公开(公告)号：US08309346B2

    公开(公告)日：2012-11-13

    申请号：US11870355

    申请日：2007-10-10

    Applicant: Ralph Zuckerman

    Inventor： Ralph Zuckerman

    IPC: C12M1/34

    CPC classification number: A61B5/0071 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14555 ,  A61B5/14556 ,  A61B5/4842 ,  A61B5/7246 ,  A61B5/7278 ,  G01N21/6445 ,  G01N21/645 ,  G01N2021/6484 ,  G01N2201/0683 ,  G01N2201/12

    Abstract: A non-invasive measurement of biological tissue reveals information about the function of that tissue. Polarized light is directed onto the tissue, stimulating the emission of fluorescence, due to one or more endogenous fluorophors in the tissue. Fluorescence anisotropy is then calculated. Such measurements of fluorescence anisotropy are then used to assess the functional status of the tissue, and to identify the existence and severity of disease states. Such assessment can be made by comparing a fluorescence anisotropy profile with a known profile of a control.

    Abstract translation: 生物组织的非侵入性测量揭示关于该组织的功能的信息。 由于组织中的一种或多种内源性荧光物质，偏振光被引导到组织上，刺激荧光的发射。 然后计算荧光各向异性。 然后使用这种荧光各向异性的测量来评估组织的功能状态，并确定疾病状态的存在和严重程度。 可以通过将荧光各向异性分布与对照的已知分布进行比较来进行这种评估。

Patent Agency Ranking