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公开(公告)号：US20240382097A1
公开(公告)日：2024-11-21
申请号：US18691924
申请日：2022-09-15
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Sung Soo Kwak , Shuai Xu , Ha UK Chung , Hyoyoung Jeong , John A. Rogers
IPC: A61B5/0205 , A61B5/00 , A61B5/01 , A61B5/02 , A61B5/021 , A61B5/024 , A61B5/08 , A61B5/113 , A61B5/145 , A61B5/257 , A61B5/263 , A61B5/28 , A61B5/296
Abstract: This invention relates to apparatuses and methods for non-invasively measuring physiological parameters of a mammal subject using easily removable flexible electronics, and applications of the same. Specifically, a novel sensor class with a pre-curved architecture and strategically located perforations that may be used in apparatuses and methods for measuring physiological parameters of a mammal subject. Further, adhesive layers are used to attach the sensor systems on the skin of the mammal subject, and each adhesive layer is switchable chemically or physically between an adhesive state and a non-adhesive state, allowing easy removal of the corresponding sensor system from the skin of the mammal subject when being switched to the non-adhesive state.
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12.发明公开公开(公告)号：US20240335657A1
公开(公告)日：2024-10-10
申请号：US18731925
申请日：2024-06-03
Applicant: Washington University , Northwestern University
Inventor： Wilson Z. Ray , Matthew R. MacEwan , Zohny S. Zohny , John A. Rogers
CPC classification number: A61N1/205 , A61N1/0456 , A61N1/0504 , A61N1/37217 , A61N1/375 , A61N1/20
Abstract: A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power.
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13.发明公开公开(公告)号：US20240269473A1
公开(公告)日：2024-08-15
申请号：US18569649
申请日：2022-06-27
Applicant: NORTHWESTERN UNIVERSITY , THE GEORGE WASHINGTON UNIVERSITY
Inventor： John A. Rogers , Yeonsik Choi , Igor Efimov , Rose T. Yin
IPC: A61N1/372 , A61L31/02 , A61L31/10 , A61L31/14 , A61N1/02 , A61N1/05 , A61N1/362 , A61N1/375 , A61N1/378 , A61N1/39
CPC classification number: A61N1/37229 , A61L31/10 , A61L31/148 , A61N1/025 , A61N1/059 , A61N1/0595 , A61N1/362 , A61N1/37512 , A61N1/3756 , A61N1/3758 , A61N1/3787 , A61N1/39622 , A61L31/022
Abstract: A device implantable on a target of interest of a subject for pacemaker, neuromodulator, and/or defibrillator therapy comprises a wireless power harvesting unit configured to deliver power via resonant inductive coupling to the target tissue for stimulation in a manner that eliminates need for batteries and allows for externalized control without transcutaneous leads. The device relies exclusively on materials that resorb when exposed to biofluids in a time-controlled manner via metabolic action and hydrolysis. The materials and design choices create a thin, flexible, and lightweight form that maintain excellent biocompatibility and stable function throughout a desired period of use. Over a subsequent timeframe following the completion of therapy, the devices disappear completely through natural biological processes. These characteristics and a miniaturized geometry facilitate full implantation into the body to eliminate the need for percutaneous hardware, which thereby minimizes the risk of device-associated infections and dislodgement.
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公开(公告)号：US20240041363A1
公开(公告)日：2024-02-08
申请号：US18036189
申请日：2021-11-10
Inventor： John A. Rogers , Wei Lu , Joseph M. Forbess , Zhi-Dong Ge
IPC: A61B5/1459 , A61B5/1455 , A61B5/0215 , A61B5/026 , A61B5/00
CPC classification number: A61B5/1459 , A61B5/14552 , A61B5/0215 , A61B5/026 , A61B5/4839 , A61B5/6852 , A61B5/0004 , A61B5/0022 , A61B2562/0247 , A61B2562/12 , A61B2562/164 , A61B2562/166
Abstract: The invention relates to an optoelectronic system. The optoelectronic system includes an optoelectronic probe operably attached to a target region of a subject; and an electronic module coupled with the optoelectronic probe for wireless, real-time, and continuous measurements of physiological information of the subj ect.
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公开(公告)号：US11860031B2
公开(公告)日：2024-01-02
申请号：US17623935
申请日：2020-07-02
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Kyeongha Kwon , Seung Yun Heo , Anthony R. Banks , John A. Rogers
CPC classification number: G01J1/429 , G01J1/0204 , G01J1/46
Abstract: A system for measuring a radiant exposure of electromagnetic radiation includes an accumulation detection module having a detector and configured to continuously monitor an electromagnetic radiation received by the detector; and an adaptive circuit configured to periodically interrogate the accumulation detection module; adjust a frequency of interrogation of the accumulation detection module based on an intensity of the electromagnetic radiation received by the detector; and autonomously transmit information related to an amount of the electromagnetic radiation received by the detector to a remote device.
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Patent Agency Ranking
16.发明授权公开(公告)号：US11832948B2
公开(公告)日：2023-12-05
申请号：US17557392
申请日：2021-12-21
Inventor： John A. Rogers , Michel Kliot , Roozbeh Ghaffari , YuHao Liu
CPC classification number: A61B5/24 , A61B5/0004 , A61B5/25 , A61B5/296 , A61B5/398 , A61B5/742 , A61N1/0456 , A61B2562/164
Abstract: The provided systems, methods and devices describe lightweight, wireless tissue monitoring devices that are capable of establishing conformal contact due to the flexibility or bendability of the device. The described systems and devices are useful, for example, for skin-mounted intraoperative monitoring of nerve-muscle activity. The present systems and methods are versatile and may be used for a variety of tissues (e.g. skin, organs, muscles, nerves, etc.) to measure a variety of different parameters (e.g. electric signals, electric potentials, electromyography, movement, vibration, acoustic signals, response to various stimuli, etc.).
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17.发明公开公开(公告)号：US20230270372A1
公开(公告)日：2023-08-31
申请号：US18014362
申请日：2021-07-08
Applicant: NORTHWESTERN UNIVERSITY
Inventor： John A. Rogers , Roozbeh Ghaffari , Kyeongha Kwon , Jong Uk Kim
IPC: A61B5/00 , A61B5/01 , G05B19/042 , F24F11/63
CPC classification number: A61B5/4266 , A61B5/6833 , A61B5/002 , A61B5/7225 , A61B5/01 , G05B19/042 , F24F11/63 , A61B2562/0271 , A61B2562/164 , G05B2219/2614
Abstract: This invention discloses a sensor for measuring parameters of sweat from a skin, comprising a flexible structure comprising a fluid passage having inlet and outlet, the flexible structure being detachably attached to the skin and configured such that sweat enters the inlet as the sweat releases from the skin and flows through the fluid passage into the outlet; a thermal actuator disposed on the flexible structure over the fluid passage and configured to operably provide heat to flow of the sweat through the fluid passage; a first thermistor disposed on the flexible structure over the fluid passage between the inlet and the thermal actuator and configured to operably measure a first temperature of the sweat thereon; and a second thermistor disposed on the flexible structure over the fluid passage between the thermal actuator and the outlet and configured to operably measure a second temperature of the sweat thereon.
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公开(公告)号：US20220125390A1
公开(公告)日：2022-04-28
申请号：US17568791
申请日：2022-01-05
Applicant: NORTHWESTERN UNIVERSITY
Inventor： John A. Rogers , Siddharth Krishnan , Tyler R. Ray , Amit B. Ayer , Philipp Gutruf , Jonathan T. Reeder , Kun Hyuck Lee , Chun-Ju Su
Abstract: Provided are conformable devices to measure subdermal fluid flow and related methods. A soft, stretchable and flexible substrate supports a thermal actuator and various specially positioned temperature sensors. A microprocessor in electronic communication with sensors calculates subdermal fluid flow from the measured upstream and downstream temperatures, as well as various application-dependent parameters. Devices and methods provided herein are particularly useful for measuring cerebral spinal fluid in a ventricular shunt placed for treatment of hydrocephalus.
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公开(公告)号：US10925523B2
公开(公告)日：2021-02-23
申请号：US16616770
申请日：2018-06-01
Inventor： John A. Rogers , Jungil Choi , Tyler R. Ray , Johnathan T. Reeder , Yurina Sekine , Amay J. Bandodkar , Yi Zhang , Hexia Guo , Sungbong Kim , Diana Ostojich
Abstract: Provided are microfluidic systems for monitoring a biofluid property and related methods. Specially configured microfluidic networks and associated structural support and functional elements, including flexible substrates, capping layers, and fluidic conduits and controllers, provide reliable biofluid collection. Optical components and indicators provide a reliable and readily observable readout, including of any of a number of biofluid properties, including directly from biofluid collected in the microfluidic network.
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20.发明授权公开(公告)号：US10653342B2
公开(公告)日：2020-05-19
申请号：US15625087
申请日：2017-06-16
Inventor： John A. Rogers , Jungil Choi , Sungbong Kim
Abstract: The invention provides systems for handling biofluids including the transport, capture, collection, storage, sensing, and/or evaluation of biofluids released by tissue. Systems of some aspects provide a versatile platform for characterization of a broad range of physical and/or chemical biofluid attributes in real time and over clinically relevant timeframes. Systems of some aspects provide for collection and/or analysis of biofluids from conformal, watertight tissue interfaces over time intervals allowing for quantitative temporal and/or volumetric characterization of biofluid release, such as release rates and release volumes.
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