公开(公告)号：US20080111071A1

公开(公告)日：2008-05-15

申请号：US11876108

申请日：2007-10-22

Applicant: Jeffery Mark Brown ,  Daniel James Kenny

Inventor： Jeffery Mark Brown ,  Daniel James Kenny

IPC: H01J49/28

CPC classification number: H01J49/405 ,  H01J49/421

Abstract: A mass filter is disclosed comprising an orthogonal acceleration electrode 9. Ions entering the mass filter are orthogonally accelerated by the orthogonal acceleration electrode 9 in a primary acceleration region 2 and enter a flight region 3. The ions 6,7,8 are then reflected by a reflectron 4 and are directed towards an exit region of the mass filter. Ions having a desired mass to charge ratio are arranged to arrive in the primary acceleration region 2 at a time when a voltage pulse applied to the orthogonal acceleration electrode 9 falls from a maximum to zero. Ions having a desired mass to charge ratio are orthogonally decelerated such that they have a zero component of velocity in the orthogonal direction. Accordingly, ions having a desired mass to charge ratio exit the mass filter in an axial direction.

Abstract translation: 公开了一种包括正交加速电极9的质量过滤器。 进入质量过滤器的离子通过正加速电极9在主加速区域2中正交加速并进入飞行区域3。 然后离子6,7,8被反射器4反射并且被引向质量过滤器的出口区域。 具有期望的质荷比的离子被布置成在施加到正交加速电极9的电压脉冲从最大值降到零的时刻到达主加速区域2。 具有期望的质荷比的离子正交减速，使得它们在正交方向上具有零分量的速度。 因此，具有期望质荷比的离子沿轴向离开质量过滤器。

公开(公告)号：US07202470B1

公开(公告)日：2007-04-10

申请号：US09787358

申请日：1999-09-16

Applicant: Philip Marriott

Inventor： Philip Marriott

IPC: H01J49/00

CPC classification number: H01J49/421 ,  H01J49/0045 ,  H01J49/04 ,  H01J49/105 ,  H01J49/22

Abstract: The present invention relates to inductively coupled plasma mass spectrometry (ICPMS) in which a collision cell is employed to selectively remove unwanted artefact ions from an ion beam by causing them to interact with a reagent gas. The present invention provides a first evacuated chamber (6) at high vacuum located between an expansion chamber (3) and a second evacuated chamber (20) containing the collision cell (24). The first evacuated chamber (6) includes a first ion optical device (17). The collision cell (24) contains a second ion optical device (25). The provision of the first evacuated chamber (5) reduces the gas load on the collision cell (24), by minimising the residual pressure within the collision cell (24) that is attributable to the gas load from the plasma source (1). This serves to minimise the formation, or re-formation, of unwanted artefact ions in the collision cell (24).

Abstract translation: 电感耦合等离子体质谱法（ICPMS）本发明涉及电感耦合等离子体质谱法（ICPMS），其中使用碰撞电池通过使其与反应气体相互作用来选择性地从离子束中去除不需要的伪影离子。 本发明提供了一种位于膨胀室（3）和包含碰撞室（24）的第二抽空室（20）之间的高真空的第一真空室（6）。 第一真空室（6）包括第一离子光学装置（17）。 碰撞单元（24）包含第二离子光学装置（25）。 通过最小化由于来自等离子体源（1）的气体负载引起的碰撞室（24）内的残余压力，第一真空室（5）的设置减少了碰撞室（24）上的气体负荷。 这用于最小化碰撞池（24）中不想要的伪影离子的形成或重新形成。

公开(公告)号：US20040222370A1

公开(公告)日：2004-11-11

申请号：US10868809

申请日：2004-06-17

Inventor： Robert Harold Bateman ,  John Brian Hoyes ,  Jason Lee Wildgoose

IPC: H01J049/00

CPC classification number: H01J49/421 ,  H01J49/0081

Abstract: A mass spectrometer includes an ion detector positioned upstream of a quadrupole mass filter/analyser. Ions are passed through the quadrupole mass filter/analyser, stored in an ion trap and then passed back through the same mass filter/analyser before being detected by the upstream ion detector. With this arrangement, MS/MS experiments can be performed using an apparatus having only a single mass filter/analyser.

Abstract translation: 质谱仪包括位于四极质量过滤器/分析器上游的离子检测器。 离子通过四极质量过滤器/分析仪，储存在离子阱中，然后通过相同的质量过滤器/分析仪通过上游离子检测器检测。 利用这种布置，可以使用仅具有单个质量过滤器/分析器的装置来执行MS / MS实验。

公开(公告)号：US06719909B2

公开(公告)日：2004-04-13

申请号：US10114900

申请日：2002-04-02

Applicant: Tihiro Ohkawa

Inventor： Tihiro Ohkawa

IPC: B03C100

CPC classification number: H01J49/421 ,  H01J49/328

Abstract: A device and method for selectively establishing predetermined orbits, relative to an axis, for ions of a first mass/charge ratio (m1), requires crossing an electric field with a substantially uniform magnetic field (E×B). The magnetic field is oriented along the axis and the electric field has both a d.c. voltage component (∇&PHgr;0) and an a.c. voltage component (∇&PHgr;1). In operation, voltage &PHgr;0 is fixed to place the ions m1 on confined orbits around the axis when &PHgr;1 is zero. On the other hand, when &PHgr;1 is tuned to a predetermined value, the ions m1 are ejected away from the axis. With E×B established in a chamber, the ions m1 will pass through the chamber when on confined orbits (&PHgr;1=0), and they will be ejected into the wall of the chamber when on unconfined orbits (&PHgr;1=predetermined value).

Abstract translation: 用于为第一质量/电荷比（m1）的离子选择性地建立相对于轴的预定轨道的装置和方法需要与具有基本均匀的磁场（ExB）的电场交叉。 磁场沿着轴定向，电场同时具有直流。 电压分量（∇Phi0）和a.c. 电压分量（∇Phi1）。 在操作中，当Phi1为零时，固定电压Phi0以将离子m1放置在围绕轴线的限制轨道上。 另一方面，当Phi1被调谐到预定值时，离子m1从轴上被排出。 当在室内建立ExB时，当在限制轨道（Phi1 = 0）时，离子m1将通过室，并且当在非限制轨道（Phi1 =预定值）时它们将被喷射到室的壁中。

公开(公告)号：US20010020679A1

公开(公告)日：2001-09-13

申请号：US09801204

申请日：2001-03-07

Inventor： Jochen Franzen

IPC: H01J049/00 ,  B01D059/44

CPC classification number: H01J49/062 ,  H01J49/004 ,  H01J49/421

Abstract: The invention relates to a tandem mass spectrometer and a method for scanning daughter ion spectra which uses a quadrupole mass spectrometer for selection of parent ions and another one for the measurement of the daughter ions. The invention consists of not using a conventional third quadrupole filter as a collision cell for fragmentation of the parent ions but an ion guide system with helically coiled wires, especially in the form of a double helix, in which the ions can be completely decelerated and can be actively fed to the outlet aperture.

Abstract translation: 本发明涉及串联质谱仪和用于扫描子离子光谱的方法，其使用四极质谱仪来选择母体离子，另一种用于测量子离子。 本发明包括不使用传统的第三四极滤波器作为用于破碎母离子的碰撞单元，而是具有螺旋线圈导线的离子导向系统，特别是双螺旋形式，其中离子可完全减速并且可以 主动进给出口孔。

公开(公告)号：US5998787A

公开(公告)日：1999-12-07

申请号：US961771

申请日：1997-10-31

Applicant: James W. Hager

Inventor： James W. Hager

IPC: H01J49/42 ,  B01D59/44 ,  H01J49/00

CPC classification number: H01J49/421 ,  H01J49/427

Abstract: A method is provided of operating a mass spectrometer having first and second rod sets, which can be a focusing set of rods and an analysis rod set, the second rod set being downstream from the first rod set at an outlet of a spectrometer. Ions are directed into the first rod set and an RF voltage applied to the two rod sets, the RF voltage can be the same or different for the two rod sets. A low level DC voltage is applied to the first rod set sufficient to reduce a continuum background ion signal, thereby to increase the signal-to-noise ratio of the spectrometer.

Abstract translation: 提供了一种操作具有第一和第二杆组的质谱仪的方法，所述第一和第二杆组可以是棒的聚焦组和分析杆组，所述第二杆组在距光谱仪出口处的第一杆的下游。 离子被引导到第一杆组和施加到两个杆组的RF电压，两个杆组的RF电压可以相同或不同。 对第一棒组施加低电平的直流电压，足以减少连续背景离子信号，从而增加光谱仪的信噪比。

公开(公告)号：US5726448A

公开(公告)日：1998-03-10

申请号：US803331

申请日：1997-02-21

Applicant: Steven Joel Smith ,  Ara Chutjian

Inventor： Steven Joel Smith ,  Ara Chutjian

IPC: B01D59/44 ,  H01J49/06 ,  H01J49/38 ,  H01J49/42

CPC classification number: H01J49/421

Abstract: A rotating field mass and velocity analyzer having a cell with four walls, time dependent RF potentials that are applied to each wall, and a detector. The time dependent RF potentials create an RF field in the cell which effectively rotates within the cell. An ion beam is accelerated into the cell and the rotating RF field disperses the incident ion beam according to the mass-to-charge (m/e) ratio and velocity distribution present in the ion beam. The ions of the beam either collide with the ion detector or deflect away from the ion detector, depending on the m/e, RF amplitude, and RF frequency. The detector counts the incident ions to determine the m/e and velocity distribution in the ion beam.

Abstract translation: 旋转的场质量和速度分析仪具有四壁的单元，施加到每个壁的时间相关的RF电位和检测器。 时间相关的RF电势在单元中产生有效地在单元内旋转的RF场。 离子束被加速到电池中，并且旋转RF场根据离子束中存在的质荷比（m / e）比和速度分布来分散入射离子束。 根据m / e，RF幅度和RF频率，光束的离子与离子检测器碰撞或偏离离子检测器。 检测器对入射离子进行计数，以确定离子束中的m / e和速度分布。

公开(公告)号：USRE35701E

公开(公告)日：1997-12-30

申请号：US623942

申请日：1996-03-29

Applicant: Paul V. Foley

Inventor： Paul V. Foley

IPC: G01N23/225 ,  H01J49/10 ,  H01J49/14 ,  H01J49/42

CPC classification number: H01J49/147 ,  H01J49/421

Abstract: A quadrupole mass spectrometer includes means for measuring total ion current having an electron repeller cage disposed about an electron source filament. The electron repeller cage repels electrons emitted by the electron source filament, urging them away from both the repeller and the filament, while also attracting positive ions. When the positive ions contact the electron repeller cage, a current is induced that is measured at the electron repeller cage. The measured current represents total ion current transmitted through the spectrometer. Thus, the need to include a total pressure measurement plate to measure total ion current is eliminated, and since the ion-exposed surface area of the electron repeller cage is greater than the ion-exposed surface area of the total pressure measurement plate, the invention provides improved total pressure measurement sensitivity.

Abstract translation: 四极质谱仪包括用于测量总离子电流的装置，其具有围绕电子源灯丝设置的电子排斥器笼。 电子反应器笼子排斥由电子源灯丝发射的电子，促使它们离开排斥器和灯丝，同时也吸引正离子。 当正离子与电子排斥笼相接触时，会产生在电子推斥器笼处测得的电流。 测量的电流表示通过光谱仪传输的总离子电流。 因此，消除了包括总压力测量板来测量总离子电流的需要，并且由于电子排斥器笼的离子暴露表面积大于总压力测量板的离子暴露表面积，所以本发明 提供改进的总压力测量灵敏度。

公开(公告)号：US3621464A

公开(公告)日：1971-11-16

申请号：US3621464D

申请日：1969-11-20

Applicant: ELECTRONIC ASSOCIATES

Inventor： BRYNDZA ROBERT M ,  WIERSMA FONGER

IPC: H01J49/42 ,  H03L5/00 ,  H03B3/02

CPC classification number: H01J49/421 ,  H01J49/022 ,  H03L5/00

Abstract: An improved radio frequency (RF) generator for use with a quadrupole mass analyzer is disclosed wherein a ramp of RF at constant frequency is provided by developing a difference signal between the output of the circuit and a control ramp input. The error signal is modulated by the desired frequency supplied from an oscillator and amplified by a push-pull arrangement. The amplified signal is applied to a series resonant tuned circuit which directly supplies the quadrupole rods.

公开(公告)号：US3487207A

公开(公告)日：1969-12-30

申请号：US3487207D

申请日：1967-04-13

Applicant: US AIR FORCE

Inventor： LANGLEY ROBERT A

IPC: H01J49/04 ,  H01J49/42 ,  H01J39/34 ,  B01D59/44

CPC classification number: H01J49/421 ,  H01J49/0009