中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

66 records (took 0.025 seconds)

    SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING
    33.
    发明申请
    SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING 有权
    硅胶水晶镜片，带有交联胶粘剂

    公开(公告)号：US20150099822A1

    公开(公告)日：2015-04-09

    申请号：US14571350

    申请日：2014-12-16

    Applicant: Novartis AG

    Inventor： Yongxing Qiu ,  Newton T. Samuel ,  John Dallas Pruitt ,  Chandana Kolluru ,  Arturo Norberto Medina ,  Lynn Cook Winterton ,  Daqing Wu ,  Xinming Qian ,  Jared Nelson

    IPC: G02B1/10 ,  G02B1/04

    CPC classification number: C09D177/06 ,  B29D11/00067 ,  C08G77/388 ,  C08J5/00 ,  C08J7/042 ,  C08J2383/04 ,  C08J2383/08 ,  C08J2433/02 ,  C08J2433/26 ,  C08J2487/00 ,  C08L83/04 ,  C09D5/1637 ,  C09D5/1681 ,  C09D133/02 ,  C09D133/14 ,  C09D133/26 ,  C09D171/02 ,  G02B1/043 ,  G02B1/10 ,  G02B1/18 ,  G02C7/049 ,  G02C2202/06 ,  G02C2202/16 ,  C08L101/14

    Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.

    Abstract translation: 本发明涉及制备其上具有交联亲水性涂层的硅氧水凝胶隐形眼镜的成本有效的方法。 本发明的方法涉及在具有带正电荷的氮杂环丁烷基团的水溶性，高度支化，热交联的亲水性聚合物材料存在下，在约40℃的温度下，在水溶液中加热硅酮水凝胶隐形眼镜 在约140℃下进行足够的时间以将可热交联的亲水聚合物材料共价连接到硅氧烷水凝胶隐形眼镜的表面上，通过共价连接，每个共价键在一个氮杂环丁烷基团和一个反应性官能团之间形成， 和/或靠近硅酮水凝胶隐形眼镜的表面，从而在硅氧水凝胶隐形眼镜上形成交联的亲水涂层。 这种方法可以有利地在高压釜中直接在密封的透镜包装中实现。

    METHOD FOR APPLYING A COATING ONTO A SILICONE HYDROGEL LENS
    34.
    发明申请
    METHOD FOR APPLYING A COATING ONTO A SILICONE HYDROGEL LENS 有权
    将涂层涂覆在硅胶水镜上的方法

    公开(公告)号：US20140174031A1

    公开(公告)日：2014-06-26

    申请号：US14101640

    申请日：2013-12-10

    Applicant: Novartis AG

    Inventor： Yongxing Qiu ,  Arturo Norberto Medina ,  John Dallas Pruitt

    IPC: G02C7/04 ,  B65B55/02

    CPC classification number: G02C7/04 ,  B29D11/00865 ,  B65B55/02 ,  G02B1/043 ,  C08L83/04 ,  C08L101/14

    Abstract: The present invention generally relates to a method for applying a coating of hydrophilic polymers onto silicone hydrogel contact lenses to improve hydrophilicity and lubricity. In particular, the present invention is directed to a method for forming a coating on a contact lens, preferably a silicone hydrogel contact lens, directly in the primary package and maintaining the coated contact lens within said primary package until insertion of the coated contact lens in the eye of the contact lens user. The resultant silicone hydrogel contact lens has a coating with good hydrophilicity, improved lubricity and good durability and also can be used directly from the lens package by a patient without washing and/or rising.

    Abstract translation: 本发明一般涉及将亲水性聚合物涂层涂覆在硅氧水凝胶隐形眼镜上以改善亲水性和润滑性的方法。 特别地，本发明涉及一种在初级包装中直接形成隐形眼镜，优选硅酮水凝胶隐形眼镜上的涂层的方法，并将涂覆的隐形眼镜保持在所述初级包装内，直到将涂覆的隐形眼镜插入 隐形眼镜用户的眼睛。 所得的硅酮水凝胶隐形眼镜具有亲水性好，润滑性好，耐久性好的涂层，也可以由患者直接从镜片包装中使用而无需洗涤和/或上升。

    WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES
    36.
    发明申请
    WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES 审中-公开

    公开(公告)号：US20190179055A1

    公开(公告)日：2019-06-13

    申请号：US16204641

    申请日：2018-11-29

    Applicant: Novartis AG

    Inventor： Yongxing Qiu ,  John Dallas Pruitt ,  Newton T. Samuel ,  Chung-Yuan Chiang ,  Robert Carey Tucker ,  Yuan Chang ,  Ethan Leveillee

    IPC: G02B1/04 ,  C08L83/04 ,  C08L33/02 ,  C09D133/02 ,  C08L79/04

    Abstract: The invention is related to contact lenses that not only comprise the much desired water gradient structural configurations, but also have a minimized uptakes of polycationic antimicrobials and a long-lasting surface hydrophilicity and wettability even after going through a 30-days lens care regime. Because of the water gradient structural configuration and a relatively-thick, extremely-soft and water-rich hydrogel surface layer, a contact lens of the invention can provide superior wearing comfort. Further, a contact lens of the invention is compatible with multipurpose lens care solutions present in the market and can endure the harsh lens care handling conditions (e.g., digital rubbings, accidental inversion of contact lenses, etc.) encountered in a daily lens care regime. As such, they are suitable to be used as weekly- or monthly-disposable water gradient contact lenses.

Patent Agency Ranking