公开(公告)号：US20240201071A1

公开(公告)日：2024-06-20

申请号：US18286602

申请日：2022-01-25

Applicant: Park Systems GmbH

Inventor： Arash Mirhamed ,  Jan-Henrik Quast ,  Matthias Duwe ,  Daniel Severins

IPC: G01N21/21 ,  G01N21/25

CPC classification number: G01N21/21 ,  G01N21/255 ,  G01N2201/0691

Abstract: A polarization measuring device is operated by passing light having a predetermined input polarization state to a sample for a potentially polarization changing interaction and from the sample through a polarization selective analyzer and to an intensity detector. The method proceeds by varying an angle between the output polarization state of the light emanating from the sample and the analyzer. The wavelength of the light reaching the intensity detector is varied, and a plurality of intensity measurements are performed successively at different constellations of polarization. Spectral modulation states and corresponding intensity values are stored together with polarization and spectral values representing the corresponding constellation. The polarization modulation and the spectral modulation are performed simultaneously and continuously, and during a single, monotonic variation of the polarization modulation state, the spectral modulation state is varied plural times and during each spectral modulation period (τλ) plural successive intensity measurements are performed.

公开(公告)号：US10345226B1

公开(公告)日：2019-07-09

申请号：US16164859

申请日：2018-10-19

Applicant: The United States of America, as represented by the Secretary of Commerce

Inventor： Young Jong Lee

IPC: G01N21/25 ,  G01N21/31

CPC classification number: G01N21/255 ,  G01N21/31 ,  G01N2201/0691

Abstract: A spectrum adjuster produces a pure analyte spectrum and includes: a dynamic opacity optic that receives input light, receives an adjustment signal, produces primary adjusted light, and produces secondary adjusted light from the input light based on the adjustment signal; a light source in optical communication with the dynamic opacity optic; a detector in optical communication with the dynamic opacity optic and that receives transmitted light from the sample and produces a transmitted light signal based on an amount of transmitted light received; and an adjustment controller that receives the transmitted light signal, produces the adjustment signal, and communicates the adjustment signal to the dynamic opacity optic.

公开(公告)号：US20180188213A1

公开(公告)日：2018-07-05

申请号：US15393342

申请日：2016-12-29

Applicant: Infineon Technologies AG

Inventor： David Tumpold ,  Gueclue Onaran ,  Christoph Glacer

IPC: G01N29/24 ,  G01N29/02

CPC classification number: G01N29/2425 ,  G01N21/1702 ,  G01N29/032 ,  G01N2021/1704 ,  G01N2021/1708 ,  G01N2201/0691 ,  G01N2291/021 ,  G01N2291/02809

Abstract: A photoacoustic gas analyzer may include: a gas chamber configured to receive a gas to be analyzed therein, a radiation source configured to emit into the gas chamber electromagnetic radiation with a time-varying intensity adapted to selectively excite gas molecules of N mutually different gas types the concentrations of which are to be determined in the gas received in the gas chamber, thereby generating acoustic waves, an acoustic-wave sensor configured to detect acoustic waves generated by the electromagnetic radiation emitted by the radiation source into the gas to be analyzed, and a control unit operatively connected to the radiation source and the acoustic-wave sensor. The control unit may be configured: to control the radiation source to emit electromagnetic radiation with a time-varying intensity and to modulate the frequency at which the intensity is varied with a modulation signal taking on at least N mutually different values, to receive from the acoustic-wave sensor signals indicative of detected acoustic waves generated by the electromagnetic radiation emitted by the radiation source into the gas to be analyzed, to determine at least N mutually different signal amplitudes associated with respective N mutually different frequencies at which the intensity of the emitted electromagnetic radiation is varied, and to determine from the determined signal amplitudes the concentrations of the N mutually different gas types.

公开(公告)号：US09841375B2

公开(公告)日：2017-12-12

申请号：US15328871

申请日：2014-08-01

Applicant: NEWPORT CORPORATION

Inventor： Anderson Chen ,  John Park

IPC: G01N21/00 ,  G01N21/55 ,  G01N21/59 ,  G01J3/02 ,  G01N21/64 ,  G01N21/47

CPC classification number: G01N21/55 ,  G01J3/00 ,  G01J3/02 ,  G01J3/0264 ,  G01J3/10 ,  G01J3/433 ,  G01J2003/104 ,  G01J2003/283 ,  G01J2003/2836 ,  G01J2003/4334 ,  G01N21/474 ,  G01N21/59 ,  G01N21/64 ,  G01N2021/556 ,  G01N2201/0691 ,  H02S50/10

Abstract: Systems for measuring optical properties of a specimen are disclosed. The systems are configured to sample signals related to the measurement of the properties of a specimen, and perform software-based coherent detection of the signals to generate resulting measurements are based on the signals acquired at substantially the same time instance. This facilitates the displaying or generating of the desired measurements in real time. In one configuration, the system is configured to direct a modulated light signal at a selected wavelength incident upon a specimen. In another configuration, the system is configured to direct a combined light signal, derived from a plurality of light signals at different wavelengths and modulated with different frequencies, incident upon a specimen. In yet another configuration, the system is configured to direct a plurality of light signals modulated with different frequencies incident upon different regions of a specimen.

公开(公告)号：US09797832B2

公开(公告)日：2017-10-24

申请号：US15027883

申请日：2015-09-23

Applicant: Siemens Aktiengesellschaft

Inventor： Franz Steinbacher

IPC: G01N21/00 ,  G01N21/39 ,  G01J3/433 ,  H01S5/062 ,  G01J3/42 ,  G01N33/00

CPC classification number: G01N21/39 ,  G01J3/42 ,  G01J3/433 ,  G01N33/0009 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/0691 ,  H01S5/06213 ,  H01S5/06216 ,  H01S5/0622

Abstract: Method and gas analyzer for measuring the concentration of a gas component in a sample gas, wherein to measure the concentration of a gas component in a sample gas, a laser diode is actuated by a current and light generated by the laser diode is guided through the sample gas to a detector, the current is simultaneously varied within periodically successive sampling intervals for the wavelength-dependent sampling of an absorption line of interest of the gas component, and the current can be additionally modulated sinusoidally based on wavelength modulation spectroscopy with a low frequency and small amplitude, such that a measuring signal generated by the detector is evaluated to form a measurement result, where to improve the measuring signal-noise ratio and achieve a much lower detection limit with the same measuring distance, the current is modulated with a high (RF) frequency in the GHz range so that no wavelength modulation occurs, and an RF modulation amplitude is selected at the maximum level using the linear control range of the laser diode where, before evaluation, the measuring signal is demodulated at the radio frequency.

公开(公告)号：US20170067822A1

公开(公告)日：2017-03-09

申请号：US15336045

申请日：2016-10-27

Applicant: NewSouth Innovations Pty Limited

Inventor： Charles Charbel HARB ,  Toby Kristian BOYSON

IPC: G01N21/39 ,  G01J3/02 ,  G01J3/433

CPC classification number: G01N21/39 ,  G01J3/0208 ,  G01J3/433 ,  G01J2003/4332 ,  G01J2003/4334 ,  G01N21/031 ,  G01N2021/391 ,  G01N2201/0691

Abstract: Methods and apparatuses (500) of generating and processing a real-time time-domain cavity ringdown spectroscopy (CRDS) signal from absorbing species m an optical detection system having an optical ringdown cavity (200) using off-axis paths (230) are provided. At least one modulated light signal (570) is generated using one or more light sources (520), each modulated at specified modulation frequency. Each modulated signal has harmonic frequency components and is input off-axis (230) relative to the cavity's optical axis (220). The cavity contains mirrors (210, 212, 214; 310; 410; 510, 512, 514) arranged in a predetermined configuration. The optical axis (220) is defined by a path passing through centers of mirrors (210, 212, 214; 310; 410; 510, 512, 514). The modulated light signal (570) is resonated off axis (230) without astigmatic optical. elements to produce CRDS signal and passes at least twice through cavity and across the mirrors (210, 212, 214; 310; 410; 510, 512, 814) without interfering, with itself. An overall path length through cavity is greater than path length of optical axis. A photodetector detects (550) the CROS signal, which is demodulated (560) dependent upon selected harmonics.

Abstract translation: 提供了在具有使用离轴路径（230）的具有光学环形腔（200）的光学检测系统中从吸收物质生成和处理实时时域空穴衰减光谱（CRDS）信号的方法和装置（500） 。 使用一个或多个光源（520）产生至少一个调制光信号（570），每个光源以规定的调制频率被调制。 每个调制信号具有谐波频率分量，并且相对于空腔的光轴（220）输入离轴（230）。 腔体包含以预定构造布置的反射镜（210,212,214; 310; 410; 510,512,514）。 光轴（220）由穿过反射镜（210,212,214; 310; 410; 510,512,514）的中心的路径限定。 调制光信号（570）在没有散光光学的情况下离轴（230）谐振。 元件以产生CRDS信号并且通过腔并至少穿过镜子（210,212,214; 310; 410; 510,512,814），而不会自身干涉。 通过腔的总路径长度大于光轴的路径长度。 光电检测器检测（550）取决于所选谐波的解调（560）的CROS信号。

公开(公告)号：US09207169B2

公开(公告)日：2015-12-08

申请号：US14381103

申请日：2013-02-19

Applicant: SIEMENS AKTIENGESELLSCHAFT

Inventor： Thomas Hankiewicz ,  Piotr Strauch

IPC: G01N21/27 ,  G01N21/31 ,  G01N21/39 ,  G01J3/10 ,  G01J3/433 ,  G01N33/00 ,  G01N21/3504

CPC classification number: G01N21/31 ,  G01J3/10 ,  G01J3/4338 ,  G01N21/3504 ,  G01N21/39 ,  G01N33/0027 ,  G01N2021/399 ,  G01N2201/0691

Abstract: A laser spectrometer and method for measuring gas component concentration in a measurement gas, wherein light intensity from a wavelength-tunable laser diode is detected after irradiation of the measurement gas and a reference gas, and the concentration of the gas component is determined based on reduction of the light intensity by the absorption of light at the position of a selected absorption line of the gas component, and the position of the absorption line of the gas component is referenced based on a selected absorption line of the reference gas, and wherein there is a mixed operation consisting of actual measurements of fast concentration changes of the gas component to be measured and a short reference/standardization phase for wavelength referencing, line locking and standardization, where the duration of the actual measurement is measured such that measuring conditions remain constant and do not deviate from those during the reference/standardization phase.

Abstract translation: 一种用于测量测量气体中的气体成分浓度的激光光谱仪和方法，其中在照射测量气体和参考气体之后检测来自波长可调激光二极管的光强度，并且基于还原确定气体成分的浓度 通过吸收在气体成分的选定吸收线的位置处的光的光强度，并且基于所选择的参考气体的吸收线来参考气体成分的吸收线的位置，并且其中存在 由待测量的气体组分的快速浓度变化的实际测量和用于波长参考，线路锁定和标准化的短参考/标准化阶段的混合操作，其中测量实际测量的持续时间，使得测量条件保持不变， 在参考/标准化阶段不要偏离。

公开(公告)号：US09096892B1

公开(公告)日：2015-08-04

申请号：US13021506

申请日：2011-02-04

Applicant: David P. Klemer ,  Daniel R. Klemer ,  Donald S. Chen ,  Jennifer S. Ito

Inventor： David P. Klemer ,  Daniel R. Klemer ,  Donald S. Chen ,  Jennifer S. Ito

IPC: C12Q1/68 ,  C12P19/34 ,  C12M1/34 ,  G01N33/543

CPC classification number: C12Q1/6827 ,  B01L7/00 ,  B01L2300/1805 ,  B01L2300/1822 ,  B01L2300/1827 ,  G01N21/0332 ,  G01N21/6428 ,  G01N33/54366 ,  G01N2201/0691

Abstract: The present invention relates generally to monitoring of biochemical amplification reactions using electromagnetic radiation, and more particularly to an apparatus for optical monitoring of isothermal and thermally-cycled amplification reactions using radiation ranging from the ultraviolet region through the infrared regions of the electromagnetic spectrum. Moreover, the method discussed herein could be similarly applied to any process that results in biochemical amplification, regardless of the specific technique employed.

Abstract translation: 本发明一般涉及使用电磁辐射监测生物化学扩增反应，更具体地涉及使用从紫外线区域到电磁光谱的红外区域的辐射进行等温和热循环扩增反应的光学监测的装置。 此外，本文讨论的方法可以类似地应用于导致生物化学扩增的任何过程，而不管所采用的具体技术如何。

公开(公告)号：US09075001B2

公开(公告)日：2015-07-07

申请号：US13998751

申请日：2013-12-03

Applicant: EMX International, LLC

Inventor： Daniel Lee Graybeal ,  Alan Carey Rogers

IPC: G01J5/02 ,  G01N21/3504 ,  G01J3/02 ,  G01J3/10

CPC classification number: G01J3/10 ,  G01J3/0205 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0245 ,  G01J3/108 ,  G01J3/42 ,  G01N21/3504 ,  G01N21/39 ,  G01N2021/399 ,  G01N2201/06113 ,  G01N2201/0612 ,  G01N2201/0691 ,  G01N2201/0697 ,  G01N2201/08 ,  H01S5/3401

Abstract: An intracavity laser absorption infrared spectroscopy system for detecting trace analytes in vapor samples. The system uses a spectrometer in communications with control electronics, wherein the control electronics contain an analyte database that contains absorption profiles for each analyte the system is used to detect. The system can not only detect the presence of specific analytes, but identify them as well. The spectrometer uses a hollow cavity waveguide that creates a continuous loop inside of the device, thus creating a large path length and eliminating the need to mechanically adjust the path length to achieve a high Q-factor. In a preferred embodiment, the laser source may serve as the detector, thus eliminating the need for a separate detector.

Abstract translation: 用于检测蒸汽样品中痕量分析物的腔内激光吸收红外光谱系统。 该系统使用光谱仪与控制电子设备进行通信，其中控制电子装置包含分析物数据库，其包含用于检测系统的每个分析物的吸收曲线。 该系统不仅可以检测特定分析物的存在，还可以识别它们。 光谱仪使用中空腔波导，其在器件内部产生连续环路，从而产生大的路径长度，并且不需要机械地调节路径长度以实现高Q因子。 在优选实施例中，激光源可以用作检测器，因此不需要单独的检测器。

公开(公告)号：US20150144791A1

公开(公告)日：2015-05-28

申请号：US14409450

申请日：2013-06-19

Applicant: KLEIN MEDICAL LIMITED

Inventor： Raymond Andrew Simpkin ,  Donal Paul Krouse ,  Bryan James Smith

IPC: G01N21/359

CPC classification number: G01J3/108 ,  G01J3/0297 ,  G01J3/28 ,  G01N21/274 ,  G01N21/3577 ,  G01N21/359 ,  G01N2201/0691

Abstract: A method and analyser for identifying, verifying or otherwise characterising a sample involves emitting electromagnetic radiation in at least one beam at a sample. The electromagnetic radiation includes at least two different wavelengths. A sample detector detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation. A processor determines sample coefficients from the output and identifies, verifies or otherwise characterises the sample using the sample coefficients and training coefficients determined from training samples. The coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.

Abstract translation: 用于识别，验证或以其他方式表征样品的方法和分析仪包括在样品的至少一个束中发射电磁辐射。 电磁辐射包括至少两个不同的波长。 样品检测器检测受样品发射的电磁辐射产生的电磁辐射，并提供表示检测到的受影响辐射的输出。 处理器从输出端确定采样系数，并使用从训练样本确定的采样系数和训练系数来识别，验证或以其他方式表征样本。 系数降低了对样品保持器变化的敏感性和/或不依赖于浓度。