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    DEEP LEARNING DRIVEN ADAPTIVE OPTICS FOR SINGLE MOLECULE LOCALIZATION MICROSCOPY
    41.
    发明申请
    DEEP LEARNING DRIVEN ADAPTIVE OPTICS FOR SINGLE MOLECULE LOCALIZATION MICROSCOPY 有权

    公开(公告)号：US20240402488A1

    公开(公告)日：2024-12-05

    申请号：US18678100

    申请日：2024-05-30

    Applicant: Purdue Research Foundation

    Inventor： Fang Huang ,  Peiyi Zhang

    IPC: G02B27/00 ,  G01N21/64 ,  G02B21/16 ,  G02B21/36 ,  G02B26/08 ,  G06T5/20 ,  G06T5/60 ,  G06T5/80 ,  G06T7/00 ,  G06T7/11

    Abstract: The invention generally relates to systems and method for deep learning driven adaptive optics for single molecule localization microscopy. In certain aspects, the invention provides a system comprising: an imaging apparatus configured for conducting single-molecule localization microscopy (SMLM), wherein the imaging apparatus comprises a deformable mirror and a dynamic filter; and a processor operably associated with the imaging apparatus. In certain embodiments, the processor is configured to: monitor individual emission patterns produced via the imaging apparatus from a plurality of different single molecules in a sample; infer shared wavefront distortion for each of the individual emission patterns; provide the shared wavefront distortion for each of the individual emission patterns through the dynamic filter; and operate the deformable mirror to compensate for sample induced aberrations.

    Sodium powders for use as electrode additives and methods of making and using the same
    43.
    发明授权
    Sodium powders for use as electrode additives and methods of making and using the same 有权

    公开(公告)号：US12159993B2

    公开(公告)日：2024-12-03

    申请号：US18199430

    申请日：2023-05-19

    Applicant: Purdue Research Foundation

    Inventor： Vilas Ganpat Pol ,  Jialiang Tang

    IPC: H01M4/139 ,  B22F1/054 ,  B22F1/18 ,  B22F9/04 ,  H01M4/04 ,  H01M4/133 ,  H01M4/1393 ,  H01M4/587 ,  H01M10/054 ,  H01M4/02

    Abstract: A method of producing metallic sodium powders. The method includes immersing one or more solid pieces of sodium metal in an organic liquid containing a hydrocarbon oil. The solid piece(s) of sodium metal immersed in the hydrocarbon oil is (are) then subjected to ultrasonic irradiation, wherein the solid piece of sodium metal is fragmented to form sodium powder, resulting in a dispersion of the sodium powder in the organic liquid. The dispersed sodium powder is then separated from the organic liquid, resulting in metallic sodium powder. A method of presodiation of an anode in an electrochemical cell. The method includes adding sodium metal powders to the surface of the anode either as a dry powder or as a suspension of the sodium particles in an organic liquid. An anode in an electrochemical cell containing metallic sodium particles. An electrochemical cell comprising a presodiated anode.

    MEMORY MANAGEMENT METHOD FOR PSEUDO-FUNCTIONAL DIFFERENTIABLE PROGRAMMING
    45.
    发明申请
    MEMORY MANAGEMENT METHOD FOR PSEUDO-FUNCTIONAL DIFFERENTIABLE PROGRAMMING 有权

    公开(公告)号：US20240393959A1

    公开(公告)日：2024-11-28

    申请号：US18689861

    申请日：2021-12-23

    Applicant: Purdue Research Foundation

    Inventor： Jeffrey M. Siskind ,  Hamad Ahmed

    IPC: G06F3/06

    Abstract: A computer-implemented method of operating on a program is disclosed which includes executing at least one instruction towards method of operating a program, the execution includes receiving request for input data associated with at least one dataset; at run time determining if the input data associated with the at least one dataset is resident on memory of one or more processors of a second class (Class2 Processors), if the associated data is resident on the memory of at least one or more processors of a first class (Class2 Processors) and not resident on the memory of the Class2 Processors, i) retrieving only the associated input data from the memory of the Classi Processors, ii) copying the associated input data onto the memory of the Class2 Processors, iii) using the retrieved input data in the execution of the at last one instruction, and iv) generating output data.

    Systems and methods for collision induced dissociation of ions in an ion trap
    46.
    发明授权
    Systems and methods for collision induced dissociation of ions in an ion trap 有权

    公开(公告)号：US12154773B2

    公开(公告)日：2024-11-26

    申请号：US17144394

    申请日：2021-01-08

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Dalton Snyder

    IPC: H01J49/00 ,  H01J49/42

    Abstract: The invention generally relates to systems and methods for collision induced dissociation of ions in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to generate one or more signals, and apply the one or more signals to the ion trap in a manner that all ions within the ion trap are fragmented at a same Mathieu q value.

    Pearl-inspired hyperspectral filter arrays
    47.
    发明授权
    Pearl-inspired hyperspectral filter arrays 有权

    公开(公告)号：US12153235B2

    公开(公告)日：2024-11-26

    申请号：US17518386

    申请日：2021-11-03

    Applicant: Purdue Research Foundation

    Inventor： Young L Kim ,  Yunsang Kwak ,  Jungwoo Leem

    IPC: G02B5/28

    Abstract: An Anderson localized hyperspectral filter array is disclosed which includes a base layer and a plurality of optical layers deposited on the base layer selected from two or more materials, each material having a refractive index that is different from the other materials of the two or more materials, wherein no consecutively deposited optical layers have the same refractive index, each of the plurality of optical layers having a thickness chosen based on a random number within a predetermined range.

    Waterproof electronic decals for wireless monitoring of biofluids
    48.
    发明授权
    Waterproof electronic decals for wireless monitoring of biofluids 有权

    公开(公告)号：US12150758B2

    公开(公告)日：2024-11-26

    申请号：US17228615

    申请日：2021-04-12

    Applicant: Purdue Research Foundation

    Inventor： Ramses Valentin Martinez ,  Aniket Pal

    IPC: H04Q9/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1491 ,  A61B5/1477

    Abstract: A wearable sensor decal may include a flexible wrapper layer, an intermediate layer, and a porous film layer. A first plurality of electrodes may be deposited on the wrapper layer. A heating element may be conductivity coupled to the first plurality of electrodes. A second plurality of electrodes may be deposited on the intermediate layer. A biosensor may be conductively coupled to the second plurality of electrodes. The flexible film may be hydrophilic to allow biofluids pass to the biosensor and the wrapper layer may be hydrophobic to provide waterproofing to the biosensor and heating element. The heating element may be powered to reduce thermal variance in biosensor measurements.

    3D TAPERED NANOPHOTONIC WAVEGUIDE TO FIBER EDGE COUPLER
    50.
    发明申请
    3D TAPERED NANOPHOTONIC WAVEGUIDE TO FIBER EDGE COUPLER 有权

    公开(公告)号：US20240369763A1

    公开(公告)日：2024-11-07

    申请号：US18228623

    申请日：2023-07-31

    Applicant: Purdue Research Foundation

    Inventor： Tzu-Han Chang ,  Chen-Lung Hung

    IPC: G02B6/122 ,  G02B6/13

    Abstract: A method of forming an optical waveguide from a multi-layer material is described. The multi-layer material includes a resist material layer deposited over a waveguide material layer, and the waveguide material layer deposited over a first cladding material layer. The method includes using a lithography procedure to form a three-dimensional tapered indentation into a top surface of the resist material layer, transferring the three-dimensional tapered indentation from the resist material layer to the waveguide material layer, forming a three-dimensional tapered optical waveguide by removing a portion of the waveguide material layer adjacent to the three-dimensional tapered indentation, and depositing a second cladding material layer over the optical waveguide to form an optical coupler having an optical input facet.

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