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    METHOD FOR DETERMINING THE MAXIMUM MASS PEAK IN MASS SPECTROMETRY
    41.
    发明申请
    METHOD FOR DETERMINING THE MAXIMUM MASS PEAK IN MASS SPECTROMETRY 有权
    用于确定质谱中最大质量峰值的方法

    公开(公告)号：US20150014523A1

    公开(公告)日：2015-01-15

    申请号：US14381170

    申请日：2013-02-28

    Applicant: Inficon GmbH

    Inventor： Norbert Rolff

    IPC: H01J49/00 ,  H01J49/26

    CPC classification number: H01J49/0036 ,  H01J49/0009 ,  H01J49/0031 ,  H01J49/26 ,  H01J49/28

    Abstract: A fast method for determining molecular mass using mass spectrometry has the following steps: specifying a first adjusting value (M1) of the mass spectrometer, recording the associated signal amplitude (A1), specifying a second adjusting value (M2) which is different to the first, measuring the associated second signal amplitude (A2), specifying a third adjusting value (M3) which is different to the first (M1) and the second (M2) adjusting value, measuring the associated third signal amplitude (A3), determining a quadratic function containing the measured amplitude values as y-values and the specified adjusting values as x-values, determining the maximum of the quadratic function, wherein the searched adjusting value is determined from the x-value of the maximum.

    Abstract translation: 使用质谱法测定分子量的快速方法具有以下步骤：指定质谱仪的第一调整值（M1），记录相关的信号幅度（A1），指定第二调整值（M2），其不同于 首先，测量相关联的第二信号幅度（A2），指定与第一（M1）和第二（M2）调整值不同的第三调整值（M3），测量相关联的第三信号幅度（A3），确定 将测量的振幅值作为y值和指定的调整值作为x值的二次函数，确定二次函数的最大值，其中根据最大值的x值确定搜索到的调整值。

    Optical bench for a mass spectrometer system
    42.
    发明授权
    Optical bench for a mass spectrometer system 有权
    光谱仪系统的光学台

    公开(公告)号：US07442920B2

    公开(公告)日：2008-10-28

    申请号：US11205758

    申请日：2005-08-16

    Applicant: Adi A. Scheidemann ,  Mark S. McGraw ,  Clare R. Long ,  Gottfried P. Kibelka

    Inventor： Adi A. Scheidemann ,  Mark S. McGraw ,  Clare R. Long ,  Gottfried P. Kibelka

    IPC: B01D59/44

    CPC classification number: H01J49/02 ,  H01J49/28 ,  H05K1/0271 ,  H05K1/0284 ,  H05K2201/2009

    Abstract: Mass spectrometer systems for measuring mass/charge ratios of analytes are described. A mass spectrometer system includes a vacuum flange, a PCB base plate coupled to the vacuum flange, and an ion optic assembly coupled to the PCB base plate. The PCB base plate may include signal-processing electronics. The system may include an electrical cable coupled to the PCB base plate for supplying power, control, and I/O to the ion optic assembly and the signal processing electronics. Alternatively, a mass spectrometer system includes a PCB base plate and an ion optic assembly. The PCB base plate has a sealant portion and an electrical portion. The ion optic assembly is coupled to the electrical portion. The system may include a vacuum housing for enclosing the ion optic assembly. The vacuum housing is coupled to the sealant portion of the PCB base plate for sustaining a vacuum while the system is in operation.

    Abstract translation: 描述了用于测量分析物质量/电荷比的质谱仪系统。 质谱仪系统包括真空法兰，联接到真空法兰的PCB基板和耦合到PCB基板的离子光学组件。 PCB基板可以包括信号处理电子器件。 该系统可以包括耦合到PCB基板的电缆，用于向离子光学组件和信号处理电子器件供电，控制和I / O。 或者，质谱仪系统包括PCB基板和离子光学组件。 PCB基板具有密封剂部分和电气部分。 离子光学组件耦合到电气部分。 该系统可以包括用于封闭离子光学组件的真空壳体。 真空壳体联接到PCB基板的密封剂部分，以在系统运行时维持真空。

    Molten salt collector for plasma separations
    43.
    发明授权
    Molten salt collector for plasma separations 失效
    用于等离子体分离的熔盐收集器

    公开(公告)号：US06632369B2

    公开(公告)日：2003-10-14

    申请号：US09903304

    申请日：2001-07-11

    Applicant: Brian P. Cluggish ,  Stephen F. Agnew ,  Sergei Putvinski

    Inventor： Brian P. Cluggish ,  Stephen F. Agnew ,  Sergei Putvinski

    IPC: B01D3506

    CPC classification number: H01J49/28

    Abstract: A collector for use in removing metal ions from a plasma in a vacuum chamber includes a collector plate that is mounted inside the chamber and formed with an internal cooling channel. An injector introduces a dissociated salt into the chamber with a first throughput value, and it introduces a plasma including metal ions into the chamber with a lower second throughput value. A pump is used to pump a liquid coolant through the cooling channel to maintain the collector plate at a temperature that forms a portion of the salt as a protective layer on the collector plate, and causes the salt to thereafter deposit on the layer in a molten condition at a faster rate than evaporation therefrom to trap metal ions therein. The trapped metal ions are then removed with the molten salt from the chamber.

    Abstract translation: 用于从真空室中的等离子体中除去金属离子的集电器包括安装在室内并形成有内部冷却通道的集电板。 注射器将解离的盐引入具有第一吞吐量值的室中，并且以较低的第二吞吐量值将包含金属离子的等离子体引入室中。 泵用于通过冷却通道泵送液体冷却剂，以将集电板保持在形成作为集电板上的保护层的盐的一部分的温度，并且使盐然后在熔融层中沉积在层上 条件比其蒸发速度更快以捕获其中的金属离子。 然后用熔融盐从室中除去捕获的金属离子

    Molten salt collector for plasma separations
    44.
    发明申请
    Molten salt collector for plasma separations 失效
    用于等离子体分离的熔盐收集器

    公开(公告)号：US20030066793A1

    公开(公告)日：2003-04-10

    申请号：US09903304

    申请日：2001-07-11

    Inventor： Brian P. Cluggish ,  Stephen F. Agnew ,  Sergei Putvinski

    IPC: B01D035/06

    CPC classification number: H01J49/28

    Abstract: A collector for use in removing metal ions from a plasma in a vacuum chamber includes a collector plate that is mounted inside the chamber and formed with an internal cooling channel. An injector introduces a dissociated salt into the chamber with a first throughput value, and it introduces a plasma including metal ions into the chamber with a lower second throughput value. A pump is used to pump a liquid coolant through the cooling channel to maintain the collector plate at a temperature that forms a portion of the salt as a protective layer on the collector plate, and causes the salt to thereafter deposit on the layer in a molten condition at a faster rate than evaporation therefrom to trap metal ions therein. The trapped metal ions are then removed with the molten salt from the chamber.

    Abstract translation: 用于从真空室中的等离子体中除去金属离子的集电器包括安装在室内并形成有内部冷却通道的集电板。 注射器将解离的盐引入具有第一吞吐量值的室中，并且以较低的第二吞吐量值将包含金属离子的等离子体引入室中。 泵用于通过冷却通道泵送液体冷却剂，以将集电板保持在形成作为集电板上的保护层的盐的一部分的温度，并且使盐然后在熔融层中沉积在层上 条件比其蒸发速度更快以捕获其中的金属离子。 然后用熔融盐从室中除去捕获的金属离子。

    Multi-mass filter
    45.
    发明授权
    Multi-mass filter 失效
    多质量过滤器

    公开(公告)号：US06293406B1

    公开(公告)日：2001-09-25

    申请号：US09643204

    申请日：2000-08-21

    Applicant: Robert L. Miller ,  Tihiro Ohkawa ,  Richard L. Freeman

    Inventor： Robert L. Miller ,  Tihiro Ohkawa ,  Richard L. Freeman

    IPC: B03C130

    CPC classification number: H01J49/28

    Abstract: A multi-mass filter for separating particles according to their mass-charge ratio includes a chamber for receiving a multi-species plasma that includes particles therein having different mass-charge ratios (with M1 Mc3) and only the intermediate particles M2 are ejected into the second region (M2>Mc2). In another embodiment, the radial electrical field is increased outwardly from the axis to a radial distance a2 (r2) at a first rate. The electrical field is then increased radially outward between a2 (r2) and a radial distance a3 (r3) at a lower rate. This electric field configuration defines the first region between the axis and a2 (r2), and the second region between a2 (r2) and a3 (r3). The third region is located radially beyond the second region. Accordingly, with Mc2=er22B2/(8*(Vctr−V2)) and Mc3=e(r32−r22)B2/(8*V2), particles M1 are confined in the first region, while both particles M3 and M2 are ejected from the first region into the second region. The particles M2 are, however, confined in the second region and only the particles M3 are ejected from the second region into the third region.

    Abstract translation: 用于根据其质荷比分离颗粒的多质量过滤器包括用于接收多种等离子体的室，其包括具有不同质荷电荷的颗粒（M1 Mc3）中，并且仅中间颗粒M2被喷射到第二区域（M2> Mc2）中。 在另一个实施例中，径向电场以第一速率从轴向外增加到径向距离a2（r2）。 然后电场以较低的速率在a2（r2）和径向距离a3（r3）之间径向向外增加。 该电场配置定义了轴和a2（r2）之间的第一区域，a2（r2）和a3（r3）之间的第二区域。 第三区域径向地位于第二区域之外。 因此，在Mc2 = er22B2 /（8 *（Vctr-V2））和Mc3 = e（r32-r22）B2 /（8 * V2）的情况下，粒子M1被限制在第一区域，同时弹出两个粒子M3和M2 从第一个地区进入第二个地区。 然而，颗粒M2被限制在第二区域中，并且仅颗粒M3从第二区域喷射到第三区域中。

    Process for the mass-spectrometric investigation of isotopes, as well as isotope mass spectrometer
    46.
    发明授权
    Process for the mass-spectrometric investigation of isotopes, as well as isotope mass spectrometer 失效
    同位素质谱检测方法以及同位素质谱仪

    公开(公告)号：US5043575A

    公开(公告)日：1991-08-27

    申请号：US480472

    申请日：1990-02-14

    Applicant: Karleugen Habfast ,  Hans-Jorg Laue

    Inventor： Karleugen Habfast ,  Hans-Jorg Laue

    IPC: B01D59/44 ,  H01J49/42

    CPC classification number: H01J49/4215 ,  B01D59/44 ,  H01J49/004 ,  H01J49/28

    Abstract: In isotope mass spectrometry, there is the problem that in the case of very great frequency differences, the less frequent masses are swamped by the more frequent masses in the measurement result or that the corresponding measurement result is falsified. A correction device is proposed, which comprises a quadrupole mass filter with a voltage supply device which is controlled by the ion separation system and is designed in such a manner that the supply voltages of the quadrupole mass filter and thus its characteristic with respect to the mass quantity to be allowed through are switched over synchronously with the varying mass deflection setting of the ion separation system.

    Abstract translation: 在同位素质谱中，存在如下问题：在频率差异非常大的情况下，较少频率的质量被测量结果中更频繁的质量淹没，或相应的测量结果被伪造。 提出了一种校正装置，其包括具有由离子分离系统控制的电压供应装置的四极质量过滤器，并且设计成使得四极质量过滤器的电源电压以及因此其相对于质量的特性 允许通过的量与离子分离系统的质量变化设定的变化同步地切换。

    Combination of time resolution and mass dispersive techniques in mass spectrometry
    48.
    发明授权
    Combination of time resolution and mass dispersive techniques in mass spectrometry 失效
    时间分辨率和质谱分析技术在质谱中的组合

    公开(公告)号：US4472631A

    公开(公告)日：1984-09-18

    申请号：US385114

    申请日：1982-06-04

    Applicant: Christie G. Enke ,  John F. Holland ,  John T. Stults

    Inventor： Christie G. Enke ,  John F. Holland ,  John T. Stults

    IPC: B01D59/44 ,  H01J49/02 ,  H01J49/32 ,  H01J49/40

    CPC classification number: H01J49/40 ,  B01D59/44 ,  H01J49/004 ,  H01J49/28

    Abstract: Time of flight mass spectrometry techniques are simultaneously combined with path-bending spatial dispersion in magnetic- or electric-sector mass spectrometers to improve the mass resolution or, with an ion fragmentation region, to rapidly obtain multidimensional mass spectral data previously only obtainable by tandem mass spectrometry. The instrumentation generates data defining relationships between parent ions and daughter ions produced by fragmentation, metastable or induced, data to differentiate stable from metastable ions, and data to improve mass resolution. The subject time-resolved mass spectrometers can be combined with chromatography apparatus to obtain multidimensional MS/MS-type data during the relatively short duration of a single chromatographic peak.

    Abstract translation: 飞行时间质谱技术与磁电或电扇区质谱仪中的路径弯曲空间色散同时组合以改善质量分辨率，或者利用离子碎片区域快速获得以前只能通过串联质量获得的多维质谱数据 光谱测定。 仪器产生的数据定义了通过断裂，亚稳态或诱导产生的亲本离子和子离子之间的关系，数据以区分稳定离子和亚稳态离子，并提供数据以改善质量分辨率。 主题时间分辨质谱仪可以与色谱装置组合，以在单个色谱峰的相对短的持续时间内获得多维MS / MS型数据。

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