公开(公告)号：US20220381737A1

公开(公告)日：2022-12-01

申请号：US17879775

申请日：2022-08-03

Applicant: FUJIFILM Corporation ,  THE UNIVERSITY OF TOKYO

Inventor： Takuro SUGIYAMA ,  Yuko TERAO ,  Yasuhiko HIRANA ,  Tetsuro OTSUKA ,  Akinori SUGISHIMA ,  Yasuharu SHIRAISHI ,  Takafumi HIRATA ,  Yoshiki MAKINO

IPC: G01N27/64 ,  H01J49/10 ,  H01J49/40

Abstract: Provided are a standard sample film for use in laser ablation inductively coupled plasma mass spectrometry, the standard sample film containing an organic substance and having a small variation in signal intensity of an ion of a metal element depending on a measurement position; a standard sample; a method for producing a standard sample film; a sample set; a quantitative analysis method; and a transfer film. The standard sample film of the present invention is a standard sample film for use in laser ablation inductively coupled plasma mass spectrometry, the standard sample film containing a polymer and a metal element, and having a maximum height difference in film thickness of the standard sample film of 0.50 μm or less.

公开(公告)号：US11515136B2

公开(公告)日：2022-11-29

申请号：US17012865

申请日：2020-09-04

Applicant: Micromass UK Limited

Inventor： Keith Richardson ,  Steven Derek Pringle ,  Julia Balog ,  Zoltan Takats

IPC: H01J49/00 ,  H01J49/04 ,  A61B10/02 ,  A61B17/32 ,  A61B18/00 ,  A61B18/14 ,  A61B18/20 ,  G01N3/00 ,  G01N9/00 ,  G01N33/68 ,  H01J49/06 ,  H01J49/16 ,  A61B90/13 ,  A61B1/04 ,  A61B1/273 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0507 ,  A61B5/055 ,  A61B6/03 ,  A61B8/13 ,  A61B10/00 ,  A61B17/00 ,  A61B18/04 ,  A61B18/18 ,  A61F13/38 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/22 ,  G01N27/622 ,  G01N27/624 ,  G01N30/72 ,  G01N33/487 ,  G01N33/92 ,  H01J49/02 ,  H01J49/10 ,  H01J49/14 ,  H01J49/24 ,  H01J49/26 ,  G16B20/00 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  A61B1/00 ,  A61B1/31 ,  A61B5/145

Abstract: A method of spectrometric analysis comprises obtaining one or more sample spectra for an aerosol, smoke or vapour sample. The one or more sample spectra are subjected to pre-processing and then multivariate and/or library based analysis so as to classify the aerosol, smoke or vapour sample. The results of the analysis are used for various surgical or non-surgical applications.

公开(公告)号：US11515135B1

公开(公告)日：2022-11-29

申请号：US16847376

申请日：2020-04-13

Applicant: Elemental Scientific, Inc.

Inventor： Daniel R. Wiederin ,  Kevin Wiederin

IPC: H01J49/04 ,  G01N35/00 ,  H01J49/10

Abstract: Systems and methods are described for indirect detection of a missed sample from an autosampler. A method embodiment includes, but is not limited to, drawing a fluid through operation of an autosampler; directing the fluid via a fluid line to a valve of a fluid handling system, the valve including or being adjacent to a sensor to detect a presence or absence of liquid sample; directing the fluid from the valve into a holding line coupled to the valve; determining whether a threshold amount of liquid sample is present in the fluid in the holding line; and when it is determined that liquid sample is present in the fluid in the holding line in an amount less than the threshold amount, transferring a carrier fluid having a marker component to an analytic detector, the marker component present in the carrier fluid in an amount indicative of a missed sample.

公开(公告)号：US20220367166A1

公开(公告)日：2022-11-17

申请号：US17746308

申请日：2022-05-17

Applicant: Micromass UK Limited

Inventor： Zoltan Takats ,  Emrys Jones ,  James Ian Langridge ,  Michael Raymond Morris ,  Tamas Karancsi ,  Steven Derek Pringle ,  Julia Balog ,  Daniel Simon ,  Lajos Godorhazy ,  Daniel Szalay ,  Keith Richardson ,  Phillip Robert Bennett ,  David Alan Macintyre ,  Pamela Pruski

IPC: H01J49/04 ,  A61B10/02 ,  A61B17/32 ,  A61B18/00 ,  A61B18/14 ,  A61B18/20 ,  G01N3/00 ,  G01N9/00 ,  G01N33/68 ,  H01J49/00 ,  H01J49/06 ,  H01J49/16 ,  A61B90/13 ,  A61B1/04 ,  A61B1/273 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0507 ,  A61B5/055 ,  A61B6/03 ,  A61B8/13 ,  A61B10/00 ,  A61B17/00 ,  A61B18/04 ,  A61B18/18 ,  A61F13/38 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/22 ,  G01N27/622 ,  G01N27/624 ,  G01N30/72 ,  G01N33/487 ,  G01N33/92 ,  H01J49/02 ,  H01J49/10 ,  H01J49/14 ,  H01J49/24 ,  H01J49/26

Abstract: A method is disclosed comprising providing a biological sample on a swab, directing a spray of charged droplets onto a surface of the swab in order to generate a plurality of analyte ions, and analysing the analyte ions.

公开(公告)号：US20220344141A1

公开(公告)日：2022-10-27

申请号：US17845156

申请日：2022-06-21

Applicant: Elemental Scientific Laser, LLC

Inventor： Ciaran J. O'Connor ,  Lief C. Summerfield

IPC: H01J49/04 ,  H01J49/10

Abstract: In an embodiment, a laser ablation system can include a laser ablation cell and at least a pair of particle-collection-to-transport-tubing interfaces. The laser ablation cell can be configured for ablating a sample or another material, and the laser ablation cell can include a laser unit. The at least a pair of particle-collection-to-transport-tubing interfaces can be configured to gather an ablated sample and direct the ablated sample to an analysis unit. A selected particle-collection-to-transport-tubing interface can be received by the laser ablation cell directly above the laser unit. The at least a pair of particle-collection-to-transport-tubing interfaces can be configured to be interchangeable with one another.

公开(公告)号：US11476778B2

公开(公告)日：2022-10-18

申请号：US16645269

申请日：2017-09-12

Applicant: Georgia Tech Research Corporation

Inventor： Anyin Li ,  Facundo Martin Fernandez ,  Yunlong Zi

IPC: H01J49/16 ,  H02N1/00 ,  H01J49/10 ,  H01J49/26

Abstract: An ion pulse generator (100) includes a triboelectric generator (110), an ion emitter (132) and a conductive surface (134). The triboelectric generator (110) includes a first electrode (114), a spaced apart second electrode (120) and a first triboelectric layer (116). The triboelectric generator (110) generates a predetermined amount of charge as a result of relative movement of the first triboelectric layer (116). The ion emitter (132) is electrically coupled to the first electrode (114). The conductive surface (134) is electrically coupled to the second electrode (120) and is spaced apart from the ion emitter (132) at a predetermined distance. Generation of the predetermined amount of charge causes formation of ions between the ion emitter (132) and the conductive surface (134).

公开(公告)号：US11476134B2

公开(公告)日：2022-10-18

申请号：US17361943

申请日：2021-06-29

Applicant: Elemental Scientific, Inc.

Inventor： Tyler Yost ,  Daniel R. Wiederin ,  Beau Marth ,  Jared Kaser ,  Jonathan Hein ,  Jae Seok Lee ,  Jae Min Kim ,  Stephen H. Sudyka

IPC: H01L21/67 ,  H01L21/66 ,  G01N21/73 ,  H01L21/677 ,  H01J49/10 ,  H01J49/00 ,  G01N33/00

Abstract: Systems and methods are described for integrated decomposition and scanning of a semiconducting wafer, where a single chamber is utilized for decomposition and scanning of the wafer of interest.

公开(公告)号：US11469090B2

公开(公告)日：2022-10-11

申请号：US17148737

申请日：2021-01-14

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Zane Baird ,  Wen-Ping Peng

IPC: H01J49/06 ,  H01J49/10 ,  H01J49/16 ,  H01J49/26

Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

公开(公告)号：US20220317563A1

公开(公告)日：2022-10-06

申请号：US17839432

申请日：2022-06-13

Applicant: FUJIFILM Corporation

Inventor： Tetsuya SHIMIZU ,  Tsukasa YAMANAKA ,  Yukihisa KAWADA

IPC: G03F1/68 ,  G03F7/40 ,  G03F7/32 ,  G03F7/11 ,  G03F7/039 ,  G03F7/16 ,  G03F7/00 ,  G03F1/86 ,  G03F7/38 ,  H01J49/10

Abstract: A container for storing a chemical fluid for manufacturing an electronic material, in which after an inspection solution charges the container and stored at 25° C. for 30 days, a sum of a concentration of particulate metal including an iron atom, a concentration of particulate metal including a copper atom, and a concentration of particulate metal including a zinc atom which are measured by a Single Particle ICP-MASS method in the inspection solution is 100 ppt or less.

公开(公告)号：US11460408B2

公开(公告)日：2022-10-04

申请号：US17122293

申请日：2020-12-15

Applicant: University of Houston System

Inventor： John F. Casey ,  Yongjun Gao ,  Weihang Yang ,  Jiaxuan Li

IPC: G01N21/73 ,  H01J49/10 ,  G01N27/62 ,  G01N1/44

Abstract: A system for geochemical characterization of a sample includes a closed reaction chamber configured to perform a high temperature and high-pressure acid digestion test, a spectrometry system configured for performing trace element analysis, and a controller. The controller includes a processor and a memory. The memory includes instructions stored thereon, which, when executed by the processor, cause the system to mineralize the sample based on a microwave process using the closed reaction chamber, and perform trace element analysis on the mineralized sample by the spectrometry system.