公开(公告)号：US11360107B1

公开(公告)日：2022-06-14

申请号：US14631830

申请日：2015-02-25

Applicant: Labrador Diagnostics LLC

Inventor： Daniel Young ,  Samartha Anekal ,  Elizabeth A. Holmes ,  Timothy Smith ,  Chinmay Pangarkar ,  James R. Wasson

IPC: G01N35/00 ,  G01N35/10 ,  C12Q3/00

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US11300564B2

公开(公告)日：2022-04-12

申请号：US15278333

申请日：2016-09-28

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Chinmay Pangarkar ,  Timothy Smith ,  Karan Mohan ,  Daniel Young ,  James Wasson ,  Samartha Anekal

IPC: G01N33/569 ,  B01L3/00 ,  G01N15/10 ,  G02B21/00 ,  G02B21/12 ,  G01N21/05 ,  G02B21/08 ,  G01N33/50 ,  G01N1/30 ,  G01N33/53 ,  G01N33/58 ,  G01N21/64 ,  G02B7/09 ,  G01N21/03 ,  G01N21/17 ,  G02B21/24 ,  G01N33/487 ,  G01N33/49 ,  G01N21/27 ,  G02B21/16 ,  G02B21/36

Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.

公开(公告)号：US11287421B2

公开(公告)日：2022-03-29

申请号：US15951641

申请日：2018-04-12

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Shaunak Roy ,  Ian Gibbons ,  Shize Daniel Qi ,  Edmond Ku ,  Chris Todd ,  Melissa Takahashi ,  Bruce Johnson ,  Jeff Fenton ,  Keith Moravick ,  Uwe Springborn ,  Anthony Delacruz

IPC: B01L99/00 ,  G01N33/53 ,  A61B5/15 ,  A61B5/1486 ,  A61B5/00 ,  G01N33/536 ,  G01N33/573 ,  A61B5/151 ,  A61B5/157

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US11275094B2

公开(公告)日：2022-03-15

申请号：US16554969

申请日：2019-08-29

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Adrit Lath

IPC: G01N35/00 ,  B01L3/00 ,  G01N35/02 ,  G01N35/10 ,  G01N35/04

Abstract: Systems and methods are provided for processing a biological sample. In one embodiment, the method comprises receiving a sample vessel containing the sample; retrieving information from an information storage unit associated with the sample; using said information for selecting at least one cartridge front at least two or more different cartridges, each configured for use with a sample processing device; loading at least one or more reagents onto the cartridge, wherein the one or more reagents to be added are selected based at least in part on the information or instructions derived from the information; and placing the sample vessel in the cartridge.

公开(公告)号：US11257215B2

公开(公告)日：2022-02-22

申请号：US16778244

申请日：2020-01-31

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes

IPC: G06T7/00 ,  G06F15/16

Abstract: Systems and methods are provided for collecting, preparing, and/or analyzing a biological sample. A sample collection site may be utilized with one or more sample processing device. The sample processing device may be configured to accept a sample from a subject. The sample processing device may perform one or more sample preparation step and/or chemical reaction involving the sample. Data related to the sample may be sent from the device to a laboratory. The laboratory may be a certified laboratory that may generate a report that is transmitted to a health care professional. The health care professional may rely on the report for diagnosing, treating, and/or preventing a disease in the subject.

公开(公告)号：US20210341500A1

公开(公告)日：2021-11-04

申请号：US17229518

申请日：2021-04-13

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Joy Roy ,  Peter Kardassakis ,  Sunny Balwani

IPC: G01N35/00 ,  B01L3/02 ,  G01N35/10 ,  G01N30/88

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US11112418B1

公开(公告)日：2021-09-07

申请号：US15664138

申请日：2017-07-31

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Daniel Young ,  Samartha Anekal ,  Chinmay Pangarkar

IPC: G01N35/00 ,  G01N15/14 ,  G01N21/01 ,  B01L3/00 ,  G01N15/00

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US11092593B2

公开(公告)日：2021-08-17

申请号：US14848084

申请日：2015-09-08

Applicant: Labrador Diagnostics LLC

Inventor： Tammy Burd ,  Ian Gibbons ,  Elizabeth A. Holmes ,  Gary Frenzel ,  Anthony Joseph Nugent

IPC: G01N33/53 ,  G16H10/40 ,  A61B5/15 ,  A61B5/151 ,  B01J19/00 ,  B01L3/02 ,  B01L3/00 ,  G01N33/543 ,  G01N33/574 ,  G01N35/00 ,  G01N35/02 ,  G01N35/10 ,  B01L7/00 ,  B01L9/00 ,  G01N1/38 ,  G01N33/569 ,  G01N33/68 ,  G01N33/94 ,  A61B10/00 ,  A61B10/02

Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

公开(公告)号：US20210140866A1

公开(公告)日：2021-05-13

申请号：US17028063

申请日：2020-09-22

Applicant: Labrador Diagnostics LLC

Inventor： Mark Dayel ,  Samartha Anekal ,  Elizabeth A. Holmes

IPC: G01N15/04 ,  G01N15/05 ,  G01N33/49

Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.

公开(公告)号：US10976330B2

公开(公告)日：2021-04-13

申请号：US15496959

申请日：2017-04-25

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Joy Roy ,  Peter Kardassakis ,  Sunny Balwani

IPC: G01N35/00 ,  B01L3/02 ,  G01N35/10 ,  G01N30/88

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.