公开(公告)号：US09606071B2

公开(公告)日：2017-03-28

申请号：US15132812

申请日：2016-04-19

Applicant: Hitachi High-Technologies Corporation

Inventor： Yukihiro Shibata ,  Hideki Fukushima ,  Yuta Urano ,  Toshifumi Honda

IPC: G01N21/956 ,  H04N5/225 ,  G01N21/95 ,  G01N21/47 ,  G06T7/00 ,  H04N5/247 ,  G01N21/17

CPC classification number: G01N21/956 ,  G01N21/47 ,  G01N21/9501 ,  G01N2021/1765 ,  G01N2201/06113 ,  G01N2201/0636 ,  G06T7/001 ,  G06T7/32 ,  G06T2207/30148 ,  H04N5/2256 ,  H04N5/247

Abstract: A defect inspection device inspecting a sample includes a movable table on which the sample as an inspection object and a pattern chip are mounted, an illumination light irradiation unit which irradiates a surface of the sample or a surface of the pattern chip with linearly-formed illumination light, a detection optical system section where a plurality of detection optical systems are disposed at a plurality of positions above the table and which detect images of scattered light generated from the sample, and a signal processing unit which processes detected signals to detect a defect of the sample surface, and a plurality of repeating patterns for generating the scattered light according to positions of the objective lenses of the plurality of detection optical systems of the detection optical system section when the linearly-formed illumination light is irradiated by the illumination light irradiation unit are periodically formed in the pattern chip.

公开(公告)号：US20170067835A1

公开(公告)日：2017-03-09

申请号：US15308001

申请日：2015-08-04

Applicant: MACHINE VISION LIGHTING INC.

Inventor： Shigeki Masumura

IPC: G01N21/88 ,  G02B27/30 ,  G02B27/14

CPC classification number: G01N21/8806 ,  G01N2201/062 ,  G01N2201/0636 ,  G01N2201/0638 ,  G01N2201/068 ,  G02B27/02 ,  G02B27/144 ,  G02B27/30

Abstract: In the inspection lighting device, between a surface light source for emitting an inspection light and the inspection object, at least one shielding mask is disposed, and a lens is disposed on a side closer to the inspection object than the shielding mask such that the shielding mask is positioned across the focus position of this lens as a center. In an irradiation solid angle of the inspection light for the inspection object formed when the light emitted from the surface light source is irradiated on to the inspection object by the lens the shielding mask forms a dark area. So that, in accordance with a change in reflection, transmission, scattering occurring at a feature point on the inspection object, a shape, a size, a tilt of the irradiation solid angle of the inspection light can be changed.

Abstract translation: 在检查照明装置中，在用于发射检查光的表面光源和检查对象之间，设置至少一个屏蔽掩模，并且在比屏蔽掩模更靠近检查对象的一侧设置透镜，使得屏蔽 面罩以该镜头的焦点位置为中心。 当通过透镜将从表面光源发射的光照射到检查对象时形成的用于检查对象的检查光的照射立体角成为暗区。 因此，根据在检查对象的特征点处发生的反射，透射，散射的变化，可以改变检查光的照射立体角的形状，尺寸，倾斜度。

公开(公告)号：US20170058310A1

公开(公告)日：2017-03-02

申请号：US15120446

申请日：2014-02-19

Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Inventor： Vincenzo CASASANTA, III

IPC: C12Q1/02 ,  G01N21/552

CPC classification number: C12Q1/02 ,  G01N21/553 ,  G01N21/554 ,  G01N2201/0628 ,  G01N2201/0636 ,  G01N2201/0683

Abstract: A biosensing device, as well as methods of forming a biosensing device and detecting presence of a biofilm are disclosed. The biosensing device may include a substrate, at least one radiation source on the substrate, at least one radiation detector on the substrate, and at least one reflector arranged on the substrate such that radiation emitted from the at least one radiation source is reflected toward the at least one radiation detector. The at least one radiation detector may be configured to detect an intensity of the radiation reflected from the at least one reflector. A biofilm growth on a portion of the at least one reflector may cause a change in the intensity of the radiation reflected from the at least one reflector relative to radiation reflected from the reflector in the absence of the biofilm growth.

Abstract translation: 公开了一种生物传感装置，以及形成生物传感装置和检测生物膜存在的方法。 生物传感装置可以包括衬底，衬底上的至少一个辐射源，衬底上的至少一个辐射检测器和布置在衬底上的至少一个反射器，使得从至少一个辐射源发射的辐射朝向 至少一个辐射检测器。 所述至少一个辐射检测器可以被配置为检测从所述至少一个反射器反射的辐射的强度。 在不存在生物膜生长的情况下，至少一个反射器的一部分上的生物膜生长可导致从至少一个反射器反射的辐射的强度相对于从反射器反射的辐射的变化。

公开(公告)号：US20160349175A1

公开(公告)日：2016-12-01

申请号：US15085782

申请日：2016-03-30

Applicant: MICROAETH CORPORATION

Inventor： Jeffrey R. Blair ,  Steven S. Blair ,  Zachary Radding ,  Kris Young

IPC: G01N21/3504 ,  G01N21/13

CPC classification number: G01N21/3504 ,  G01N21/13 ,  G01N21/59 ,  G01N21/8483 ,  G01N35/00009 ,  G01N2021/135 ,  G01N2201/0636

Abstract: An apparatus for receiving an analyte comprises two opposing housings that clamp onto a substrate. One of the housings includes passageways that deliver the analyte and optical signals to the substrate. Another one of the housings includes passageways that allow optical signals, which have passed through the substrate, to travel to photometric sensors which may be used to study the analyte or its effects. The apparatus may include a light guide that uniformly distributes light from a plurality of point emitters to multiple areas of the substrate. The apparatus may include an actuator assembly that opens and closes the two housing to allow for installation and removal of the substrate. The substrate may be carried in a cartridge that is removable from the two housings.

Abstract translation: 用于接收分析物的装置包括夹在基板上的两个相对的壳体。 其中一个外壳包括将分析物和光学信号传递到基底的通道。 另一个外壳包括允许已经通过基板的光信号行进到可用于研究分析物或其影响的光度传感器的通道。 该装置可以包括将来自多个点发射器的光均匀地分布到衬底的多个区域的光导。 该装置可以包括致动器组件，该致动器组件打开和关闭两个壳体以允许安装和移除基板。 衬底可以被携带在可从两个壳体移除的盒中。

公开(公告)号：US20160320310A1

公开(公告)日：2016-11-03

申请号：US15107910

申请日：2013-12-26

Applicant: POSCO

Inventor： Jae Hwa HONG

IPC: G01N21/84 ,  G01N21/55

CPC classification number: G01N21/8422 ,  G01B11/0616 ,  G01N21/25 ,  G01N21/55 ,  G01N2021/8427 ,  G01N2201/0636

Abstract: An apparatus for simultaneously measuring whiteness and coating amount, according to one embodiment of the present invention, comprises: a light-emitting unit arranged at a predetermined distance from a test piece and irradiating the test piece with light; a filter unit arranged between the light-emitting unit and the test piece and allowing either an infrared ray or a visible ray to selectively pass therethrough; a detection unit arranged at a predetermined distance from the test piece and detecting either the infrared ray or the visible ray to be reflected from the test piece; and a calculation unit connected with the detection unit, calculating the coating amount according to the amount of the infrared ray detected by the detection unit, and calculating the whiteness according to the amount of the visible ray detected by the detection unit. Since the whiteness and the coating amount can be measured by the apparatus for simultaneously measuring the whiteness and the coating amount according to one embodiment of the present invention, work efficiency is increased and capital expenditure for equipment can be reduced.

Abstract translation: 根据本发明的一个实施例的用于同时测量白度和涂布量的装置包括：发射单元，其布置成距离测试件预定距离并且用光照射测试片; 布置在所述发光单元和所述测试片之间并且允许红外线或可见光线选择性地通过的滤光器单元; 检测单元，其布置在距离测试件预定距离处，并检测要从测试片反射的红外线或可见光线; 以及与所述检测单元连接的计算单元，根据由所述检测单元检测到的红外线的量来计算涂布量，并且根据由所述检测单元检测到的可见光的量来计算白度。 由于根据本发明的一个实施方案，通过用于同时测量白度和涂布量的装置可以测量白度和涂布量，因此提高了工作效率，并且可以减少设备的资本支出。

公开(公告)号：US20160313258A1

公开(公告)日：2016-10-27

申请号：US15132323

申请日：2016-04-19

Applicant: CAMTEK LTD.

Inventor： Noam Gordon ,  Itay Cohen

IPC: G01N21/95 ,  G02B27/10 ,  G02B27/09 ,  H04N5/225 ,  G02B17/08

CPC classification number: G01N21/9515 ,  G01N2201/0636 ,  G01N2201/0638 ,  G02B19/0023 ,  G02B19/0028 ,  G02B19/0047 ,  H04N5/2254 ,  H04N5/2256 ,  H04N5/3692

Abstract: An inspection system having an expanded angular coverage, the inspection system may include a line camera; a first curved mirror; a second curved mirror; a first focusing lens that is positioned between the first mirror and an object; a second focusing lens that is positioned between the second mirror and the object; a first light source that is configured to direct a first part of a first light beam towards the first curved mirror and a second part of the first light beam towards the first focusing lens; a second light source that is configured to direct a first part of a second light beam towards the second curved mirror and a second part of the second light beam towards the second focusing lens.

Abstract translation: 具有扩大的角度覆盖的检查系统，检查系统可以包括线路相机; 第一个曲面镜; 第二个曲面镜; 位于第一反射镜和物体之间的第一聚焦透镜; 位于第二反射镜和物体之间的第二聚焦透镜; 第一光源，其被配置为将第一光束的第一部分朝向第一弯曲镜引导，并且第一光束的第二部分朝向第一聚焦透镜; 第二光源，被配置为将第二光束的第一部分引向第二曲面镜，第二光束的第二部分朝向第二聚焦透镜。

公开(公告)号：US20160252453A1

公开(公告)日：2016-09-01

申请号：US14787953

申请日：2014-06-06

Applicant: MALVERN INSTRUMENTS LIMITED

Inventor： E. Neil LEWIS

IPC: G01N21/53 ,  G01N21/41 ,  G01N21/33 ,  G01N21/05

CPC classification number: G01N21/53 ,  G01N15/1463 ,  G01N21/05 ,  G01N21/33 ,  G01N21/41 ,  G01N21/4133 ,  G01N21/6452 ,  G01N21/6454 ,  G01N21/6458 ,  G01N2201/06113 ,  G01N2201/0636 ,  G01N2201/068 ,  G01N2201/12

Abstract: An optical sample characterization method is disclosed comprising: holding a sample in a sample container proximate at least one two-dimensional detector array assembly, wherein the sample container has a first end and a second end; setting up a gradient between the first end of the sample container and the second end of the sample container; illuminating the sample between the first end of the sample container and the second end of the sample container; and detecting light received from the illuminated sample from the first end of the sample container to the second end of the sample container by the two-dimensional array assembly.

Abstract translation: 公开了一种光学样品表征方法，包括：将样品保持在靠近至少一个二维检测器阵列组件的样品容器中，其中样品容器具有第一端和第二端; 在样品容器的第一端和样品容器的第二端之间建立一个梯度; 在样品容器的第一端和样品容器的第二端之间照射样品; 以及通过所述二维阵列组件将从所述照射样品接收的光从所述样品容器的第一端检测到所述样品容器的第二端。

公开(公告)号：US20160178522A1

公开(公告)日：2016-06-23

申请号：US14997883

申请日：2016-01-18

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael R. GAMBINI ,  Edward J. LAKATOS ,  Anthony L. CERRONE ,  Eugene F. YOUNG ,  John G. ATWOOD

IPC: G01N21/64

CPC classification number: G01N21/6428 ,  B01L3/5085 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/1811 ,  C12Q1/686 ,  C12Q2545/101 ,  G01N21/274 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/0245 ,  G01N2201/06113 ,  G01N2201/0628 ,  G01N2201/0635 ,  G01N2201/0636 ,  G01N2201/068 ,  C12Q2563/107

Abstract: An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.

Abstract translation: 光学仪器监测具有温度循环阻滞的反应装置中DNA的PCR复制，所述反应装置具有小瓶的反应成分，包括在双链DNA存在下发荧光的染料。 分束器将激发光束传递到小瓶以使染料发荧光。 来自染料的发射光束通过分束器传递到CCD检测器，处理器从该CCD检测器计算DNA浓度。 具有多个参考发射器的参考条发射不同强度的参考光束，处理器从该参考光束选择用于补偿漂移的最佳发射器。 自动调整曝光时间以保持CCD和处理器的最佳动态范围。 分束器和相关的滤光器的模块与选定的染料相关联，并且可替代不同的染料。

公开(公告)号：US09267883B2

公开(公告)日：2016-02-23

申请号：US14362725

申请日：2012-11-29

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： James Russell

IPC: G01J5/02 ,  G01N21/3504 ,  G01N21/03 ,  G01N21/85 ,  A61B5/083 ,  A61M16/10 ,  G01N33/00 ,  G01N33/50

CPC classification number: G01N21/3504 ,  A61B5/0836 ,  A61M16/1005 ,  A61M2016/102 ,  G01N21/031 ,  G01N21/85 ,  G01N33/0027 ,  G01N33/50 ,  G01N2021/8578 ,  G01N2201/0636

Abstract: A gas measurement module (16) for use with an airway adapter (22) is configured such that both an emitter (48) and a detector (52, 54) are disposed on the same side of a sampling chamber (46) formed within the airway adapter. Optical elements (56) that guide electromagnetic radiation from the emitter back and forth across the sampling chamber to the detector include at least one toric element. The at least one toric element compensates for a tilted folding mirror positioned on a side of the sampling chamber opposite from the emitter and the detector.

Abstract translation: 与气道适配器（22）一起使用的气体测量模块（16）被配置成使得发射器（48）和检测器（52,54）都设置在形成在所述气道适配器（22）内的取样室（46）的同一侧 气道适配器。 将来自发射器的来自发射器的电磁辐射引导穿过采样室到检测器的光学元件（56）包括至少一个复曲面元件。 至少一个复曲面元件补偿位于与发射器和检测器相对的取样室侧面上的倾斜折叠镜。

公开(公告)号：US20150355081A1

公开(公告)日：2015-12-10

申请号：US14637094

申请日：2015-03-03

Applicant: MKS Instruments, Inc.

Inventor： Charles Mark Phillips ,  Barbara Marshik-Geurts ,  Leonard I. Kamlet ,  Martin L. Spartz ,  Vidi Saptari

IPC: G01N21/3504 ,  G01J3/453 ,  G01N21/45

CPC classification number: G01N21/3504 ,  G01J3/02 ,  G01J3/0291 ,  G01J3/42 ,  G01J3/453 ,  G01N21/031 ,  G01N21/05 ,  G01N21/09 ,  G01N21/45 ,  G01N2021/3595 ,  G01N2201/061 ,  G01N2201/0636 ,  G01N2201/1293

Abstract: A method is provided for monitoring one or more silicon-containing compounds present in a biogas. The method includes generating a first absorption spectrum based on a ratio of a first spectral measurement and a second spectral measurement. The first spectral measurement is from a non-absorptive gas having substantially no infrared absorptions in a specified wavelength range of interest and the second spectral measurement is from a sample gas comprising the biogas. The method includes generating at least one surrogate absorption spectrum based on, at least, individual absorption spectrum for each of a subset of one or more silicon-containing compounds selected from a larger set of known silicon-containing compounds with known concentrations. A total concentration of the one or more silicon-containing compounds in the biogas can be calculated based on the first absorption spectrum and the at least one surrogate absorption spectrum.

Abstract translation: 提供了一种用于监测存在于沼气中的一种或多种含硅化合物的方法。 该方法包括基于第一光谱测量和第二光谱测量的比率产生第一吸收光谱。 第一光谱测量来自在感兴趣的特定波长范围内基本上没有红外吸收的非吸收性气体，并且第二光谱测量来自包括生物气体的样品气体。 所述方法包括基于选自具有已知浓度的较大组已知含硅化合物的一种或多种含硅化合物的子集中的每一个，至少基于至少单独的吸收光谱产生至少一种替代吸收光谱。 可以基于第一吸收光谱和至少一个替代吸收光谱来计算生物气体中一种或多种含硅化合物的总浓度。