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    QUANTIFICATION METHOD OF IMPURITIES IN LACTIDE
    61.
    发明申请
    QUANTIFICATION METHOD OF IMPURITIES IN LACTIDE 审中-公开
    LACTIDE中染色体的定量方法

    公开(公告)号：US20160299071A1

    公开(公告)日：2016-10-13

    申请号：US15038583

    申请日：2014-12-08

    Applicant: PURAC BIOCHEM BV

    Inventor： Gerrit GOBIUS DU SART ,  Jan Arie NIESSEN ,  Vincent DE JONG

    IPC: G01N21/59 ,  C07D319/12

    CPC classification number: G01N21/59 ,  C07D319/12 ,  G01N21/359 ,  G01N2201/0826 ,  G01N2201/12

    Abstract: A method for quantification of the amount of impurities in lactide. The method is characterized in that the quantification of the impurities is based on measurements performed on absorptions in the near Infra-Red region of the electromagnetic spectrum. With this method, small amounts of impurities like water, free-acid species or both can be determined online in a reaction mixture of lactide in a relatively simple manner. This allows a simple online monitoring of the production process of lactide.

    Abstract translation: 用于定量丙交酯中的杂质量的方法。 该方法的特征在于杂质的定量是基于对电磁光谱的近红外区域的吸收进行的测量。 通过这种方法，可以在相对简单的方式在丙交酯的反应混合物中在线测定少量的杂质如水，游离酸物质或两者。 这允许简单的在线监测丙交酯的生产过程。

    TISSUE PATHLENGTH RESOLVED NONINVASIVE ANALYZER APPARATUS AND METHOD OF USE THEREOF
    64.
    发明申请
    TISSUE PATHLENGTH RESOLVED NONINVASIVE ANALYZER APPARATUS AND METHOD OF USE THEREOF 审中-公开
    组织病理解析非分析分析仪器及其使用方法

    公开(公告)号：US20150018642A1

    公开(公告)日：2015-01-15

    申请号：US13941369

    申请日：2013-07-12

    Applicant: Sandeep Gulati ,  Thomas George ,  Timothy Ruchti ,  Alan Abul-Haj ,  Kevin H. Hazen

    Inventor： Sandeep Gulati ,  Thomas George ,  Timothy Ruchti ,  Alan Abul-Haj ,  Kevin H. Hazen

    IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145

    CPC classification number: G01J3/42 ,  A61B5/0022 ,  A61B5/1079 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/6801 ,  G01N21/474 ,  G01N2021/4742 ,  G01N2021/4747 ,  G01N2201/0826

    Abstract: An analyzer apparatus and method of use thereof is configured to dynamically interrogate a sample. For example, an analyzer using light interrogates a tissue sample using a temporal resolution system on a time scale of less than about one hundred nanoseconds. Optionally, near-infrared photons are introduced to a sample with a known illumination zone to detection zone distance allowing calculation of parameters related to photon pathlength in tissue and/or molar absorptivity of an individual or group through the use of the speed of light and/or one or more indices of refraction. Optionally, more accurate estimation of tissue properties are achieved through use of: knowledge of incident photon angle relative to skin, angularly resolved detector positions, anisotropy, skin temperature, environmental information, information related to contact pressure, blood glucose concentration history, and/or a skin layer thickness, such as that of the epidermis and dermis.

    Abstract translation: 分析装置及其使用方法被配置为动态询问样品。 例如，使用光的分析器使用时间分辨率系统在小于约百纳秒的时间尺度上询问组织样品。 可选地，将近红外光子引入具有已知照明区域到检测区距离的样品，允许通过使用光速和/或光速计算与组织中的光子路径长度和/或个体或组的摩尔吸光度相关的参数， 或一个或多个折射率。 任选地，通过使用以下方式实现对组织性质的更准确的估计：相对于皮肤的入射光子角度的知识，角度分辨的检测器位置，各向异性，皮肤温度，环境信息，与接触压力相关的信息，血糖浓度历史和/或 皮肤层厚度，如表皮和真皮层。

    REACTION CONTAINER AND METHOD FOR PRODUCING SAME
    65.
    发明申请
    REACTION CONTAINER AND METHOD FOR PRODUCING SAME 审中-公开
    反应容器及其生产方法

    公开(公告)号：US20140048540A1

    公开(公告)日：2014-02-20

    申请号：US14000832

    申请日：2011-08-19

    Applicant: Hideji Tajima

    Inventor： Hideji Tajima

    IPC: B65D6/00

    CPC classification number: B65D7/12 ,  B01L3/50855 ,  B01L3/523 ,  B01L3/5635 ,  B01L7/52 ,  B01L2200/028 ,  B01L2300/044 ,  B01L2300/0832 ,  B01L2300/1805 ,  B01L2300/1822 ,  G01N2201/0826

    Abstract: The invention relates to a reaction container and a method for producing the reaction container, and provides a low-cost reaction container which is capable of consistently, quickly, and efficiently performing a process that includes a reaction such as extraction or amplification of a nucleic acid, while saving user's trouble without increasing the scale of the device.The reaction container is configured to comprise: one or two or more housing parts for reactions comprising: a narrow-mouthed piping part in which a reaction reagent or a portion thereof is housed or is housable; a wide-mouthed piping part that is communicated with the narrow-mouthed piping part and provided on an upper side of the narrow-mouthed piping part, and has an aperture that is wider than an aperture of the narrow-mouthed piping part; and a punchable film provided such that it partitions an interval between the wide-mouthed piping part and the narrow-mouthed piping part.

    Abstract translation: 本发明涉及反应容器和反应容器的制造方法，提供一种低成本的反应容器，其能够一贯地，快速地且有效地进行包括诸如提取或扩增核酸的反应的方法 同时在不增加设备规模的同时节省用户的麻烦。 反应容器被构造成包括：用于反应的一个或两个或更多个壳体部分，包括：窄口管道部分，反应试剂或其一部分容纳在其中或可容纳的; 与狭窄的管道部分连通并设置在狭窄的管道部分的上侧的宽口管部分，并且具有比窄口管道部分的孔宽的孔; 以及设置成使得其在宽口管道部分和窄口管道部分之间隔开间隔的可冲压膜。

    BIOCHEMICAL REACTIONS SYSTEM
    66.
    发明申请
    BIOCHEMICAL REACTIONS SYSTEM 审中-公开
    生化反应体系

    公开(公告)号：US20140011266A1

    公开(公告)日：2014-01-09

    申请号：US13639584

    申请日：2011-04-06

    Applicant: IT-IS INTERNATIONAL LIMITED

    Inventor： Benjamin Masterman Webster ,  James Richard Howell

    IPC: B01L7/00

    CPC classification number: B01L7/52 ,  B01L3/50851 ,  B01L3/50853 ,  B01L2300/046 ,  B01L2300/0654 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2300/1894 ,  G01N21/0332 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: A chemical and/or biochemical system (1) having at least one reaction vessel (3) in which chemical and/or biochemical reactions may take place, the temperature of the reaction vessels being cycled between at least a highest predetermined temperature and a lowest predetermined temperature, the system comprising a thermal mount (4) for receiving the reaction vessel (s), the thermal mount being thermally coupled to a first, thermally conductive side of a thermoelectric module (5), a second thermally conductive side of the thermoelectric module being thermally coupled to a heat sink (6) and being provided with a pair of electrical contacts (33) to which a pair of electrically conductive wires (34) is connected for coupling to a power source, characterized in that a flexible adhesive (31, 32) is provided between the first thermally conductive side of the thermoelectric module and the thermal mount and between the second thermally conductive side of the thermoelectric module and the heat sink, whereby the adhesive is relatively thermally insulating compared to the first and second thermally conductive sides of the thermoelectric module and forms the sole coupling, thermal or mechanical, between the thermoelectric module and the thermal mount and between the thermoelectric module and the heat sink.

    Abstract translation: 化学和/或生化系统（1）具有至少一个其中可能发生化学和/或生物化学反应的反应容器（3），反应容器的温度在至少最高预定温度和最低预定温度之间循环 所述系统包括用于接收所述反应容器的热安装座（4），所述热安装件热耦合到热电模块（5）的第一导热侧，所述热电模块的第二导热侧 被热耦合到散热器（6）并且设置有一对电触点（33），一对导电线（34）连接到所述一对电触头（34）以耦合到电源，其特征在于，柔性粘合剂（31） ，32）设置在热电模块的第一导热侧和热座之间以及热电模块的第二导热侧之间，并且热sin k，由此与热电模块的第一和第二导热侧相比，粘合剂相对热绝缘，并且在热电模块和热安装座之间以及热电模块和散热器之间形成热耦合或机械的单独耦合。

    Photonic measurement instrument using fiber optics
    67.
    发明授权
    Photonic measurement instrument using fiber optics 有权
    使用光纤的光子测量仪器

    公开(公告)号：US08541741B2

    公开(公告)日：2013-09-24

    申请号：US12949383

    申请日：2010-11-18

    Applicant: Juan C. Ivaldi ,  Paul L. St. Cyr ,  Eugene Chow ,  Mark C. Werner

    Inventor： Juan C. Ivaldi ,  Paul L. St. Cyr ,  Eugene Chow ,  Mark C. Werner

    IPC: G01J5/00

    CPC classification number: G01N21/3103 ,  G01N21/3151 ,  G01N21/68 ,  G01N21/72 ,  G01N21/74 ,  G01N2201/082 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: A photonic measurement system, such as an atomic absorption spectrometer, includes source, sample and detection modules that are interconnected by fiber optic cables. A first set of fiber optic cables guides light from one or more light sources in the source module to each of at least two analysis chambers in the sample module. A second set of fiber optic cables guides light from the analysis chambers to a detector in the detection module. The detector provides to a processing sub-system signals that correspond to intensities of the guided light. One analysis chamber is selected to perform a sample analysis at a given time, and the processing sub-system processes the signals associated with the selected analysis chamber as measurement signals. The processing sub-system may further process the signals associated with a given non-selected analysis chamber as reference signals.

    Abstract translation: 诸如原子吸收光谱仪的光子测量系统包括通过光纤电缆互连的源，样本和检测模块。 第一组光纤电缆将源模块中的一个或多个光源的光引导到样品模块中的至少两个分析室中的每一个。 第二组光纤电缆将来自分析室的光引导到检测模块中的检测器。 检测器向处理子系统提供对应于导光的强度的信号。 选择一个分析室以在给定时间执行样本分析，并且处理子系统处理与所选分析室相关联的信号作为测量信号。 处理子系统可以进一步处理与给定的非选择分析室相关联的信号作为参考信号。

    PHOTONIC MEASUREMENT INSTRUMENT USING FIBER OPTICS
    69.
    发明申请
    PHOTONIC MEASUREMENT INSTRUMENT USING FIBER OPTICS 有权
    光纤测量仪器使用光纤光学

    公开(公告)号：US20110122396A1

    公开(公告)日：2011-05-26

    申请号：US12949383

    申请日：2010-11-18

    Applicant: Juan C. Ivaldi ,  Paul L. St. Cyr ,  Eugene Chow ,  Mark C. Werner

    Inventor： Juan C. Ivaldi ,  Paul L. St. Cyr ,  Eugene Chow ,  Mark C. Werner

    IPC: G01J3/28 ,  G01J3/00 ,  G01J3/30

    CPC classification number: G01N21/3103 ,  G01N21/3151 ,  G01N21/68 ,  G01N21/72 ,  G01N21/74 ,  G01N2201/082 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: A photonic measurement system, such as an atomic absorption spectrometer, includes source, sample and detection modules that are interconnected by fiber optic cables. A first set of fiber optic cables guides light from one or more light sources in the source module to each of at least two analysis chambers in the sample module. A second set of fiber optic cables guides light from the analysis chambers to a detector in the detection module. The detector provides to a processing sub-system signals that correspond to intensities of the guided light. One analysis chamber is selected to perform a sample analysis at a given time, and the processing sub-system processes the signals associated with the selected analysis chamber as measurement signals. The processing sub-system may further process the signals associated with a given non-selected analysis chamber as reference signals.

    Abstract translation: 诸如原子吸收光谱仪的光子测量系统包括通过光纤电缆互连的源，样本和检测模块。 第一组光纤电缆将源模块中的一个或多个光源的光引导到样品模块中的至少两个分析室中的每一个。 第二组光纤电缆将来自分析室的光引导到检测模块中的检测器。 检测器向处理子系统提供对应于导光的强度的信号。 选择一个分析室以在给定时间执行样本分析，并且处理子系统处理与所选分析室相关联的信号作为测量信号。 处理子系统可以进一步处理与给定的非选择分析室相关联的信号作为参考信号。

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